Publications by authors named "Hua-Lin Wu"

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Validation of the therapeutic potential of soluble CD93 lectin-like domain in arthritis and its inhibitory role in inflammatory osteolysis.
Shang-En Huang, Cheng-Hsiang Kuo, Hua-Lin Wu, Erna Sulistyowati, Fang-Tzu Lee, Jwu-Lai Yeh

Int Immunopharmacol· December 2025

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Plasminogen deficiency reduces disease severity and immune responses in enterovirus A71-infected mice.
Zheng-Xun Li, Ya-Fang Wang, Li-Ting Chiang, Li-Jin Hsu, Shih-Min Wang, Hua-Lin Wu

Microbiol Spectr· July 2025

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Correction: Interference in melanoma CD248 function reduces vascular mimicry and metastasis.
Cheng-Hsiang Kuo, Ya-Fang Wu, Bi-Ing Chang, Chao-Kai Hsu, Chao-Han Lai, Hua-Lin Wu

J Biomed Sci· July 2025

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Deciphering the Dysregulating IGF-1-SP1-CD248 Pathway in Fibroblast Functionality during Diabetic Wound Healing.
Ya-Chu Ku, Yao-Chou Lee, Yi-Kai Hong, Yung-Ling Lo, Cheng-Hsiang Kuo, Hua-Lin Wu

J Invest Dermatol· May 2025

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CD248 deficiency promotes angiotensin II-induced aortic lesion by attenuating receptor stability in smooth muscle cells.
Tai-Tzu Hsieh, Ya-Chu Ku, Chu-Jen Chen, Cheng-Hsiang Kuo, Bi-Ing Chang, Hua-Lin Wu

Clin Transl Med· May 2025

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C-reactive protein to albumin ratio combined with the Systemic Inflammatory Response Index predicts the prognosis of patients undergoing radical hepatectomy.
Shao-Long Lu, Qing-Yuan Zhang, Yuan-Quan Zhao, Hua-Lin Wu, Jie Lin

BMC Cancer· April 2025

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Studying the role of thrombomodulin-plasminogen interaction in spatial and interfacial invasion of melanoma metastatic progression.
Thi Kim Ngan Ngo, Hua-Lin Wu, Cheng-Hsiang Kuo, Ting-Yuan Tu

Int J Biol Macromol· January 2025

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Calcium phosphate complex of recombinant human thrombomodulin promote bone formation in interbody fusion.
Cheng-Li Lin, Yu-Wei Chen, Cheng-Hsiang Kuo, Ting-Yuan Tu, Hua-Lin Wu

Biofabrication· October 2024

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Regulation of matrix reloading by tumor endothelial marker 1 protects against abdominal aortic aneurysm.
Yi-Kai Hong, Tsung-Lin Cheng, Chao-Kai Hsu, Fang-Tzu Lee, Bi-Ing Chang, Hua-Lin Wu

Int J Biol Sci· August 2024

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Breaking the symmetry of cell contractility drives tubulogenesis via CXCL1 polarization.
Cheng-Hsiang Kuo, Gang-Hui Lee, Hua-Lin Wu, Jyun-Yuan Huang, Ming-Jer Tang

Proc Natl Acad Sci U S A· February 2024

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CD248 Regulates Inflammation and Encapsulation in Silicone-Related Capsule Formation.
Tzu-Yen Chang, Yi-Kai Hong, Yao-Lung Kuo, Hua-Lin Wu, Shyh-Jou Shieh

Plast Reconstr Surg· January 2024

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CD248 promotes insulin resistance by binding to the insulin receptor and dampening its insulin-induced autophosphorylation.
Patricia O Benedet, Nooshin S Safikhan, Maria J Pereira, Bryan M Lum, José Diego Botezelli, Hua-Lin Wu

EBioMedicine· January 2024

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TEM1/endosialin/CD248 promotes pathologic scarring and TGF-β activity through its receptor stability in dermal fibroblasts.
Yi-Kai Hong, Yu-Chen Lin, Tsung-Lin Cheng, Chao-Han Lai, Yi-Han Chang, Chen-Han Wu, Hua-Lin Wu

J Biomed Sci· January 2024

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Soluble CD93 lectin-like domain sequesters HMGB1 to ameliorate inflammatory diseases.
Shang-En Huang, Cheng-Hsiang Kuo, Si-Yu Shiao, Chia-Rui Shen, Fang-Tzu Lee, Hua-Lin Wu, Jwu-Lai Yeh

Theranostics· August 2023

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Chondrocyte Thrombomodulin Protects against Osteoarthritis.
Lin Kang, Ai-Lun Yang, Chao-Han Lai, Tsan-Ju Chen, Sung-Yen Lin, Hua-Lin Wu

Int J Mol Sci· May 2023

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Interference in melanoma CD248 function reduces vascular mimicry and metastasis.
Cheng-Hsiang Kuo, Ya-Fang Wu, Bi-Ing Chang, Chao-Kai Hsu, Chao-Han Lai, Hua-Lin Wu

J Biomed Sci· November 2022

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CD248 Regulates Wnt Signaling in Pericytes to Promote Angiogenesis and Tumor Growth in Lung Cancer.
Chia-Lun Hong, I-Shing Yu, Chen-Hsueh Pai, Jin-Shing Chen, Min-Shu Hsieh, Hua-Lin Wu

Cancer Res· October 2022

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Absence of the lectin-like domain of thrombomodulin reduces HSV-1 lethality of mice with increased microglia responses.
Meng-Shan Tsai, Li-Chiu Wang, Hua-Lin Wu, Shun-Fen Tzeng, Edward M Conway

J Neuroinflammation· March 2022

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Recombinant thrombomodulin domain 1 rescues pathological angiogenesis by inhibition of HIF-1α-VEGF pathway.
Yi-Hsun Huang, Cheng-Hsiang Kuo, I-Chen Peng, Yi-Sheng Chang, Sung-Huei Tseng, Hua-Lin Wu

Cell Mol Life Sci· December 2021

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Recombinant thrombomodulin lectin-like domain attenuates Porphyromonas gingivalis lipopolysaccharide-induced osteoclastogenesis and periodontal bone resorption.
Lan-Yun Chang, Chao-Han Lai, Cheng-Hsiang Kuo, Bi-Ing Chang, Hua-Lin Wu

J Periodontol· November 2021

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Microglia Reduce Herpes Simplex Virus 1 Lethality of Mice with Decreased T Cell and Interferon Responses in Brains.
Meng-Shan Tsai, Li-Chiu Wang, Hsien-Yang Tsai, Yu-Jheng Lin, Hua-Lin Wu

Int J Mol Sci· November 2021

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Nanostructured Lipid Carrier Gel Formulation of Recombinant Human Thrombomodulin Improve Diabetic Wound Healing by Topical Administration.
Yuan-Shuo Hsueh, Yan-Jye Shyong, Hsiu-Ching Yu, Shu-Jhen Jheng, Shang-Wen Lin, Hua-Lin Wu

Pharmaceutics· September 2021

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Role of tumor endothelial marker 1 (Endosialin/CD248) lectin-like domain in lipopolysaccharide-induced macrophage activation and sepsis in mice.
Tsung-Lin Cheng, Yu-Syuan Lin, Yi-Kai Hong, Chih-Yuan Ma, Hung-Wen Tsai, Hua-Lin Wu

Transl Res· June 2021

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VEGF-Induced Endothelial Podosomes via ROCK2-Dependent Thrombomodulin Expression Initiate Sprouting Angiogenesis.
Cheng-Hsiang Kuo, Yi-Hsun Huang, Po-Ku Chen, Gang-Hui Lee, Ming-Jer Tang, Hua-Lin Wu

Arterioscler Thromb Vasc Biol· May 2021

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Targeting fibroblast CD248 attenuates CCL17-expressing macrophages and tissue fibrosis.
Chen-Hsueh Pai, Shu-Rung Lin, Chia-Hao Liu, Szu-Yu Pan, Hao Hsu, Hua-Lin Wu

Sci Rep· October 2020

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