Publications by authors named "Yan-Jye Shyong"

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Variations in ECM Topography, Fiber Alignment, Mechanical Stiffness, and Cellular Composition Between Ventral and Dorsal Ligamentum Flavum Layers: Insights Into Hypertrophy Pathogenesis.
Ting-Yuan Tu, Yu-Chia Hsu, Chia-En Yang, Yan-Jye Shyong, Cheng-Hsiang Kuo

JOR Spine· March 2025

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Delivery of extracellular vesicles loaded with immune checkpoint inhibitors for immunotherapeutic management of glioma.
Shang-Wen Lin, Cheng-Ping Yu, Jui-Chen Tsai, Yan-Jye Shyong

Mater Today Bio· October 2024

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Calcium phosphate complex of recombinant human thrombomodulin promote bone formation in interbody fusion.
Cheng-Li Lin, Yu-Wei Chen, Cheng-Hsiang Kuo, Ting-Yuan Tu, Hua-Lin Wu, Yan-Jye Shyong

Biofabrication· October 2024

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BMSC loaded photo-crosslinked hyaluronic acid/collagen hydrogel incorporating FG4592 for enhanced cell proliferation and nucleus pulposus differentiation.
Cheng-Li Lin, Yu-Wen Su, Yu-Wei Chen, Cheng-Hsiang Kuo, Ting-Yuan Tu, Yan-Jye Shyong

Int J Biol Macromol· July 2024

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Amphiphilic NLC-Gel formulation loaded with Sebacoyl dinalbuphine ester and Nalbuphine for localized postoperative pain management.
Cheng-Li Lin, Yi-Lian Li, Yu-Wei Chen, Cheng-Hsiang Kuo, Ting-Yuan Tu, Yan-Jye Shyong

Int J Pharm· June 2024

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Long acting tariquidar loaded stearic acid-modified hydroxyapatite enhances brain penetration and antitumor effect of temozolomide.
Cheng-Ping Yu, Shang-Wen Lin, Jui-Chen Tsai, Yan-Jye Shyong

Eur J Pharm Biopharm· April 2024

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Porous hydroxyapatite carrier enables localized and sustained delivery of honokiol for glioma treatment.
Feng-Huei Lin, Yu-Chen Hsu, Kuo-Chi Chang, Yan-Jye Shyong

Eur J Pharm Biopharm· August 2023

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Drug delivery of extracellular vesicles: Preparation, delivery strategies and applications.
Shang-Wen Lin, Jui-Chen Tsai, Yan-Jye Shyong

Int J Pharm· July 2023

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Administration of N-Acetylcysteine to Regress the Fibrogenic and Proinflammatory Effects of Oxidative Stress in Hypertrophic Ligamentum Flavum Cells.
Yu-Chia Hsu, Hao-Chun Chuang, Kun-Ling Tsai, Ting-Yuan Tu, Yan-Jye Shyong

Oxid Med Cell Longev· November 2022

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Ligand design for human acetylcholinesterase and nicotinic acetylcholine receptors, extending beyond the conventional and canonical.
Palmer Taylor, Yan-Jye Shyong, Nathan Samskey, Kwok-Yiu Ho, Zoran Radic'

J Neurochem· September 2021

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Enhancing Target Tissue Levels and Diminishing Plasma Clearance of Ionizing Zwitterionic Antidotes in Organophosphate Exposures.
Yan-Jye Shyong, Yadira Sepulveda, Arnold Garcia, Nathan M Samskey, Zoran Radic

J Pharmacol Exp Ther· September 2021

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Nanostructured Lipid Carrier Gel Formulation of Recombinant Human Thrombomodulin Improve Diabetic Wound Healing by Topical Administration.
Yuan-Shuo Hsueh, Yan-Jye Shyong, Hsiu-Ching Yu, Shu-Jhen Jheng, Shang-Wen Lin

Pharmaceutics· September 2021

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Effects of Highly Oxygenated Water in a Hyperuricemia Rat Model.
Chih-Hsiang Fang, Cheng-Chia Tsai, Yan-Jye Shyong, Chun-Ting Yang, Keng-Yuan Li

J Healthc Eng· May 2021

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Topical application of sebacoyl dinalbuphine ester-loaded nanostructured lipid carriers alleviate pruritus in scratching mouse model.
Shang-Wen Lin, Yan-Jye Shyong, Ping-Chung Kuo, Jui-Chen Tsai

Int J Pharm· May 2021

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Oxidative stress mediates age-related hypertrophy of ligamentum flavum by inducing inflammation, fibrosis, and apoptosis through activating Akt and MAPK pathways.
Hao-Chun Chuang, Kun-Ling Tsai, Kuen-Jer Tsai, Ting-Yuan Tu, Yan-Jye Shyong

Aging (Albany NY)· November 2020

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Development of an In Vitro 3D Model for Investigating Ligamentum Flavum Hypertrophy.
Cheng-Li Lin, Yi-Ting Kuo, Che-Hao Tsao, Yan-Jye Shyong, Shu-Hsien Shih

Biol Proced Online· September 2020

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Assessment of ionizable, zwitterionic oximes as reactivating antidotal agents for organophosphate exposure.
Palmer Taylor, Shyong Yan-Jye, Jeremiah Momper, William Hou, Gisela Andrea Camacho-Hernandez

Chem Biol Interact· August 2019

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Calcium phosphate particles stimulate exosome secretion from phagocytes for the enhancement of drug delivery.
Yan-Jye Shyong, Kuo-Chi Chang, Feng-Huei Lin

Colloids Surf B Biointerfaces· November 2018

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Post-exposure treatment with the oxime RS194B rapidly reactivates and reverses advanced symptoms of lethal inhaled paraoxon in macaques.
Yvonne J Rosenberg, Jerry Wang, Tara Ooms, Narayanan Rajendran, Lingjun Mao, Yan-Jye Shyong

Toxicol Lett· September 2018

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Mesoporous hydroxyapatite as a carrier of olanzapine for long-acting antidepression treatment in rats with induced depression.
Yan-Jye Shyong, Mao-Hsien Wang, Li-Wei Kuo, Chang-Fu Su, Wei-Ting Kuo

J Control Release· June 2017

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Development of gelatin nanoparticles conjugated with phytohemagglutinin erythroagglutinating loaded with gemcitabine for inducing apoptosis in non-small cell lung cancer cells.
Wei-Ting Kuo, Jian-Yuan Huang, Min-Hua Chen, Ching-Yun Chen, Yan-Jye Shyong

J Mater Chem B· April 2016

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Mesoporous Hydroxyapatite as Olanzapine Carrier Provides a Long-Acting Effect in Antidepression Treatment.
Yan-Jye Shyong, Mao-Hsien Wang, Hsiang-Chien Tseng, Chen Cheng, Kuo-Chi Chang

J Med Chem· November 2015

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