Publications by authors named "Hubert Gstach"

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Towards the Use of Metabolic Volatiles in Breath for Determining Drug Response: Gstachamine as an Unlabeled Substrate to Measure CYP3A4 Activity.
Valentina Stock, Rebecca Hofer, Klaus R Liedl, Jakob Troppmair, Thierry Langer, Hubert Gstach

ChemMedChem· September 2025

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Diisopromine as a non-labelled CYP3A4 substrate: Implications for breath test development.
Valentina Stock, Rebecca Hofer, Vera A Spanke, Klaus R Liedl, Jakob Troppmair, Hubert Gstach

Bioorg Chem· August 2025

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FAHD1 and mitochondrial metabolism: a decade of pioneering discoveries.
Elia Cappuccio, Max Holzknecht, Michèle Petit, Anne Heberle, Yana Rytchenko, Hubert Gstach

FEBS J· June 2025

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Tolterodine is a novel candidate for assessing CYP3A4 activity through metabolic volatiles to predict drug responses.
Valentina Stock, Rebecca Hofer, Franziska Lochmann, Vera Spanke, Klaus R Liedl, Hubert Gstach

Sci Rep· January 2025

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Chirality Matters: Fine-Tuning of Novel Monoamine Reuptake Inhibitors Selectivity through Manipulation of Stereochemistry.
Predrag Kalaba, Katharina Pacher, Philip John Neill, Vladimir Dragacevic, Martin Zehl, Hubert Gstach

Biomolecules· September 2023

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Inhibitors of Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1).
Alexander K H Weiss, Richard Wurzer, Patrycia Klapec, Manuel Philip Eder, Johannes R Loeffler, Hubert Gstach

Molecules· August 2021

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Regulation of cellular senescence by eukaryotic members of the FAH superfamily - A role in calcium homeostasis?
Alexander K H Weiss, Eva Albertini, Max Holzknecht, Elia Cappuccio, Ilaria Dorigatti, Hubert Gstach

Mech Ageing Dev· September 2020

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A Many-Faced Alkaloid: Polymorphism of (-)-Monophyllidin.
Christian Dank, Richard Wurzer, Susanne Felsinger, Ricarda Bugl, Hanspeter Kählig, Hubert Gstach

Molecules· January 2020

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Expression, Purification, Crystallization, and Enzyme Assays of Fumarylacetoacetate Hydrolase Domain-Containing Proteins.
Alexander K H Weiss, Max Holzknecht, Elia Cappuccio, Ilaria Dorigatti, Karin Kreidl, Hubert Gstach

J Vis Exp· June 2019

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Structural basis for the bi-functionality of human oxaloacetate decarboxylase FAHD1.
Alexander K H Weiss, Andreas Naschberger, Johannes R Loeffler, Hubert Gstach, Matthew W Bowler

Biochem J· November 2018

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The fumarylacetoacetate hydrolase (FAH) superfamily of enzymes: multifunctional enzymes from microbes to mitochondria.
Alexander K H Weiss, Johannes R Loeffler, Klaus R Liedl, Hubert Gstach, Pidder Jansen-Dürr

Biochem Soc Trans· April 2018

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Hybrids of salicylalkylamides and Mannich bases: control of the amide conformation by hydrogen bonding in solution and in the solid state.
Christian Dank, Barbara Kirchknopf, Matthias Mastalir, Hanspeter Kählig, Susanne Felsinger, Hubert Gstach

Molecules· January 2015

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Identification and X-ray co-crystal structure of a small-molecule activator of LFA-1-ICAM-1 binding.
Martin Hintersteiner, Jörg Kallen, Mario Schmied, Christine Graf, Thomas Jung, Hubert Gstach

Angew Chem Int Ed Engl· April 2014

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Identification of a small molecule inhibitor of importin β mediated nuclear import by confocal on-bead screening of tagged one-bead one-compound libraries.
Martin Hintersteiner, Géza Ambrus, Janna Bednenko, Mario Schmied, Andrew J S Knox, Hubert Gstach

ACS Chem Biol· October 2010

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Terminal adenosyl transferase activity of posttranscriptional regulator HuR revealed by confocal on-bead screening.
Nicole-Claudia Meisner, Martin Hintersteiner, Jan-Marcus Seifert, Roman Bauer, Roger Marc Benoit, Hubert Gstach

J Mol Biol· February 2009

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Sulfonamido-aryl ethers as bradykinin B1 receptor antagonists.
Andrew G Cole, Axel Metzger, Marc-Raleigh Brescia, Lan-Ying Qin, Kenneth C Appell, Hubert Gstach

Bioorg Med Chem Lett· January 2009

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The chemical hunt for the identification of drugable targets.
Nicole-Claudia Meisner, Martin Hintersteiner, Volker Uhl, Thomas Weidemann, Mario Schmied, Hubert Gstach

Curr Opin Chem Biol· August 2004

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