Publications by authors named "Martin Hintersteiner"

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Quantitative characterisation of extracellular vesicles designed to decoy or compete with SARS-CoV-2 reveals differential mode of action across variants of concern and highlights the diversity of Omicron.
Melanie Schürz, Isabel Pagani, Eva Klinglmayr, Heloisa Melo Benirschke, Martin Mayora Neto, Martin Hintersteiner

Cell Commun Signal· July 2025

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Quantitative and functional characterisation of extracellular vesicles after passive loading with hydrophobic or cholesterol-tagged small molecules.
Gwenola Tréton, Claudia Sayer, Melanie Schürz, Maria Jaritsch, Anna Müller, Martin Hintersteiner

J Control Release· September 2023

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EVAnalyzer: High content imaging for rigorous characterisation of single extracellular vesicles using standard laboratory equipment and a new open-source ImageJ/Fiji plugin.
Melanie Schürz, Joachim Danmayr, Maria Jaritsch, Eva Klinglmayr, Heloisa Melo Benirschke, Martin Hintersteiner

J Extracell Vesicles· December 2022

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Facile Synthesis of a Next Generation Safety-Catch Acid-Labile Linker, SCAL-2, Suitable for Solid-Phase Synthesis, On-Support Display and for Post-Synthesis Tagging.
Christophe Portal, Martin Hintersteiner, Olivier Barbeau, Peter Dodd, Margaret Huggett

ChemistrySelect· August 2017

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A Wide-Field Fluorescence Microscope Extension for Ultrafast Screening of One-Bead One-Compound Libraries Using a Spectral Image Subtraction Approach.
Wolf Heusermann, Beat Ludin, Nhan T Pham, Manfred Auer, Thomas Weidemann, Martin Hintersteiner

ACS Comb Sci· May 2016

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Dynamics and interaction of interleukin-4 receptor subunits in living cells.
Hetvi Gandhi, Remigiusz Worch, Kristina Kurgonaite, Martin Hintersteiner, Petra Schwille

Biophys J· December 2014

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Identification and X-ray co-crystal structure of a small-molecule activator of LFA-1-ICAM-1 binding.
Martin Hintersteiner, Jörg Kallen, Mario Schmied, Christine Graf, Thomas Jung

Angew Chem Int Ed Engl· April 2014

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The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing.
Lukas Stalder, Wolf Heusermann, Lena Sokol, Dominic Trojer, Joel Wirz, Martin Hintersteiner

EMBO J· April 2013

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A two-channel detection method for autofluorescence correction and efficient on-bead screening of one-bead one-compound combinatorial libraries using the COPAS fluorescence activated bead sorting system.
Martin Hintersteiner, Manfred Auer

Methods Appl Fluoresc· March 2013

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On-bead screens sample narrower affinity ranges of protein-ligand interactions compared to equivalent solution assays.
Martin Hintersteiner, Christof Buehler, Manfred Auer

Chemphyschem· October 2012

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Towards mimicking short linear peptide motifs: identification of new mixed α,β-peptidomimetic ligands for SLAM-Associated Protein (SAP) by confocal on-bead screening.
Martin Hintersteiner, Andrew J Knox, Gemma Mudd, Manfred Auer

J Chem Biol· April 2012

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Single cell analysis of ligand binding and complex formation of interleukin-4 receptor subunits.
Thomas Weidemann, Remigiusz Worch, Kristina Kurgonaite, Martin Hintersteiner, Christian Bökel

Biophys J· November 2011

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Identification of a small molecule inhibitor of importin β mediated nuclear import by confocal on-bead screening of tagged one-bead one-compound libraries.
Martin Hintersteiner, Géza Ambrus, Janna Bednenko, Mario Schmied, Andrew J S Knox

ACS Chem Biol· October 2010

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Analysis of protein-small molecule interactions by microscale equilibrium dialysis and its application as a secondary confirmation method for on-bead screening.
Thomas Weidemann, Jan-Marcus Seifert, Martin Hintersteiner, Manfred Auer

J Comb Chem· September 2010

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Confocal nanoscanning, bead picking (CONA): PickoScreen microscopes for automated and quantitative screening of one-bead one-compound libraries.
Martin Hintersteiner, Christof Buehler, Volker Uhl, Mario Schmied, Jürgen Müller

J Comb Chem· December 2009

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Single bead labeling method for combining confocal fluorescence on-bead screening and solution validation of tagged one-bead one-compound libraries.
Martin Hintersteiner, Thierry Kimmerlin, Frank Kalthoff, Markus Stoeckli, Geraldine Garavel

Chem Biol· July 2009

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A highly potent and cellularly active beta-peptidic inhibitor of the p53/hDM2 interaction.
Martin Hintersteiner, Thierry Kimmerlin, Geraldine Garavel, Thorsten Schindler, Roman Bauer

Chembiochem· April 2009

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Terminal adenosyl transferase activity of posttranscriptional regulator HuR revealed by confocal on-bead screening.
Nicole-Claudia Meisner, Martin Hintersteiner, Jan-Marcus Seifert, Roman Bauer, Roger Marc Benoit

J Mol Biol· February 2009

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Single-bead, single-molecule, single-cell fluorescence: technologies for drug screening and target validation.
Martin Hintersteiner, Manfred Auer

Ann N Y Acad Sci· July 2008

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Covalent fluorescence labeling of His-tagged proteins on the surface of living cells.
Martin Hintersteiner, Thomas Weidemann, Thierry Kimmerlin, Nimet Filiz, Christof Buehler

Chembiochem· June 2008

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Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR.
Nicole-Claudia Meisner, Martin Hintersteiner, Kurt Mueller, Roman Bauer, Jan-Marcus Seifert

Nat Chem Biol· August 2007

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In vivo detection of amyloid-beta deposits by near-infrared imaging using an oxazine-derivative probe.
Martin Hintersteiner, Albert Enz, Peter Frey, Anne-Lise Jaton, Willy Kinzy

Nat Biotechnol· May 2005

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The chemical hunt for the identification of drugable targets.
Nicole-Claudia Meisner, Martin Hintersteiner, Volker Uhl, Thomas Weidemann, Mario Schmied

Curr Opin Chem Biol· August 2004

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