Publications by authors named "Gemma Mudd"

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Design of Bicyclic Peptide Tandems Mimicking the Homodimeric GDF15 Protein to Inhibit GDF15-GFRaL-RET Complex Cell Signaling.
Anaïs F M Noisier, Jenny Sandmark, Fredrik Edfeldt, Anna Backmark, Johan Broddefalk, Gemma E Mudd

J Med Chem· October 2025

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Development and preclinical characterization of a novel radiotheranostic EphA2-targeting bicyclic peptide.
Mohamed El Fakiri, Anusha R Regupathy, Lisa Uhlmann, Nawal Ayada, Nicolas M Geis, Gemma E Mudd

Theranostics· September 2024

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Discovery and Characterization of a Bicyclic Peptide (Bicycle) Binder to Thymic Stromal Lymphopoietin.
Frank Narjes, Fredrik Edfeldt, Jens Petersen, Linda Öster, Corinne Hamblet, Gemma E Mudd

J Med Chem· February 2024

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BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors.
Michael Rigby, Gavin Bennett, Liuhong Chen, Gemma E Mudd, Helen Harrison

Mol Cancer Ther· December 2022

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Discovery of BT8009: A Nectin-4 Targeting Bicycle Toxin Conjugate for the Treatment of Cancer.
Gemma E Mudd, Heather Scott, Liuhong Chen, Katerine van Rietschoten, Gabriela Ivanova-Berndt

J Med Chem· November 2022

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Gold-Mediated Multiple Cysteine Arylation for the Construction of Highly Constrained Bicycle Peptides.
Gemma E Mudd, Steven J Stanway, David R Witty, Alex Thomas, Silvia Baldo

Bioconjug Chem· August 2022

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Discovery and Optimization of a Synthetic Class of Nectin-4-Targeted CD137 Agonists for Immuno-oncology.
Punit Upadhyaya, Julia Kristensson, Johanna Lahdenranta, Elizabeth Repash, Jun Ma, Gemma E Mudd

J Med Chem· July 2022

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Comprehensive Surfaceome Profiling to Identify and Validate Novel Cell-Surface Targets in Osteosarcoma.
Yifei Wang, Xiangjun Tian, Wendong Zhang, Zhongting Zhang, Rossana Lazcano, Gemma Mudd

Mol Cancer Ther· June 2022

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Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist.
Punit Upadhyaya, Johanna Lahdenranta, Kristen Hurov, Sailaja Battula, Rachel Dods, Gemma Mudd

J Immunother Cancer· January 2021

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MMAE Delivery Using the Toxin Conjugate BT5528.
Gavin Bennett, Amy Brown, Gemma Mudd, Philip Huxley, Katerine Van Rietschoten

Mol Cancer Ther· July 2020

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Identification and Optimization of EphA2-Selective Bicycles for the Delivery of Cytotoxic Payloads.
Gemma E Mudd, Amy Brown, Liuhong Chen, Katerine van Rietschoten, Sophie Watcham

J Med Chem· April 2020

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Bicyclic Peptides as a New Modality for Imaging and Targeting of Proteins Overexpressed by Tumors.
Matthias Eder, Silvia Pavan, Ulrike Bauder-Wüst, Katerine van Rietschoten, Ann-Christin Baranski, Gemma Mudd

Cancer Res· February 2019

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Complementary Benzophenone Cross-Linking/Mass Spectrometry Photochemistry.
Adam Belsom, Gemma Mudd, Sven Giese, Manfred Auer, Juri Rappsilber

Anal Chem· May 2017

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A general synthetic route to isomerically pure functionalized rhodamine dyes.
Gemma Mudd, Irene Pérez Pi, Nicholas Fethers, Peter G Dodd, Olivier R Barbeau

Methods Appl Fluoresc· October 2015

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Identification and X-ray co-crystal structure of a small-molecule activator of LFA-1-ICAM-1 binding.
Martin Hintersteiner, Jörg Kallen, Mario Schmied, Christine Graf, Thomas Jung, Gemma Mudd

Angew Chem Int Ed Engl· April 2014

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Towards mimicking short linear peptide motifs: identification of new mixed α,β-peptidomimetic ligands for SLAM-Associated Protein (SAP) by confocal on-bead screening.
Martin Hintersteiner, Andrew J Knox, Gemma Mudd, Manfred Auer

J Chem Biol· April 2012

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