Publications by authors named "Gavin Bennett"

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Results From First-in-Human Phase I Dose-Escalation Study of a Novel Bicycle Toxin Conjugate Targeting EphA2 (BT5528) in Patients With Advanced Solid Tumors.
Babar Bashir, Judy S Wang, Gerald Falchook, Elisa Fontana, Hendrik-Tobias Arkenau, Gavin Bennett

J Clin Oncol· October 2024

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Bioanalysis of the Bicycle toxin conjugate BT5528 and released monomethyl auristatin E via liquid chromatography-tandem mass spectrometry.
Joseph A Tweed, Fern Adams-Dam, Jane Allanson, Kevin Holmes, Ryan Senior, Gavin Bennett

Bioanalysis· February 2024

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BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors.
Michael Rigby, Gavin Bennett, Liuhong Chen, Gemma E Mudd, Helen Harrison

Mol Cancer Ther· December 2022

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Development of a LC-MS/MS method for the quantification of toxic payload DM1 cleaved from BT1718 in a Phase I study.
Catherine Gowland, Philip Berry, Julie Errington, Phillip Jeffrey, Gavin Bennett

Bioanalysis· January 2021

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MMAE Delivery Using the Toxin Conjugate BT5528.
Gavin Bennett, Amy Brown, Gemma Mudd, Philip Huxley, Katerine Van Rietschoten

Mol Cancer Ther· July 2020

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Identification and Optimization of EphA2-Selective Bicycles for the Delivery of Cytotoxic Payloads.
Gemma E Mudd, Amy Brown, Liuhong Chen, Katerine van Rietschoten, Sophie Watcham, Gavin S Bennett

J Med Chem· April 2020

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Investigation of Fugitive Aerosols Released into the Environment during High-Flow Therapy.
James A McGrath, Ciarraí O'Toole, Gavin Bennett, Mary Joyce, Miriam A Byrne

Pharmaceutics· June 2019

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In Vitro Study of the Effect of Breathing Pattern on Aerosol Delivery During High-Flow Nasal Therapy.
Gavin Bennett, Mary Joyce, Louise Sweeney, Ronan MacLoughlin

Pulm Ther· June 2019

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Comparison of aerosol delivery across combinations of drug delivery interfaces with and without concurrent high-flow nasal therapy.
Gavin Bennett, Mary Joyce, Elena Fernández Fernández, Ronan MacLoughlin

Intensive Care Med Exp· April 2019

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Bicyclic Peptides as a New Modality for Imaging and Targeting of Proteins Overexpressed by Tumors.
Matthias Eder, Silvia Pavan, Ulrike Bauder-Wüst, Katerine van Rietschoten, Ann-Christin Baranski, Gavin Bennett

Cancer Res· February 2019

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Investigation of the Quantity of Exhaled Aerosols Released into the Environment during Nebulisation.
James A McGrath, Andrew O'Sullivan, Gavin Bennett, Ciarraí O'Toole, Mary Joyce

Pharmaceutics· February 2019

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In Vitro Determination of the Main Effects in the Design of High-Flow Nasal Therapy Systems with Respect to Aerosol Performance.
Gavin Bennett, Mary Joyce, Louise Sweeney, Ronan MacLoughlin

Pulm Ther· June 2018

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Stable and Long-Lasting, Novel Bicyclic Peptide Plasma Kallikrein Inhibitors for the Treatment of Diabetic Macular Edema.
Daniel P Teufel, Gavin Bennett, Helen Harrison, Katerine van Rietschoten, Silvia Pavan

J Med Chem· April 2018

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CZ415, a Highly Selective mTOR Inhibitor Showing in Vivo Efficacy in a Collagen Induced Arthritis Model.
Andrew D Cansfield, Tammy Ladduwahetty, Mihiro Sunose, Katie Ellard, Rosemary Lynch, Gavin Bennett

ACS Med Chem Lett· August 2016

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A rapid and transient peripheral inflammatory response precedes brain inflammation after experimental stroke.
Katie Z Chapman, Verity Q Dale, Adám Dénes, Gavin Bennett, Nancy J Rothwell

J Cereb Blood Flow Metab· November 2009

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Optimization of a series of multi-isoform PI3 kinase inhibitors.
Benjamin Perry, Rebekah Beevers, Gavin Bennett, George Buckley, Tom Crabbe

Bioorg Med Chem Lett· October 2008

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Achieving multi-isoform PI3K inhibition in a series of substituted 3,4-dihydro-2H-benzo[1,4]oxazines.
Benjamin Perry, Rikki Alexander, Gavin Bennett, George Buckley, Tom Ceska

Bioorg Med Chem Lett· August 2008

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Re: Moral distress of staff nurses in a medical intensive care unit.
Gavin Bennett

Am J Crit Care· March 2006

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Chondroitinase ABC promotes functional recovery after spinal cord injury.
Elizabeth J Bradbury, Lawrence D F Moon, Reena J Popat, Von R King, Gavin S Bennett

Nature· April 2002

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