Publications by authors named "Hui-Song Pak"

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A comprehensive proteogenomic pipeline for neoantigen discovery to advance personalized cancer immunotherapy.
Florian Huber, Marion Arnaud, Brian J Stevenson, Justine Michaux, Fabrizio Benedetti, HuiSong Pak

Nat Biotechnol· August 2025

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Phage display enables machine learning discovery of cancer antigen-specific TCRs.
Giancarlo Croce, Rachid Lani, Delphine Tardivon, Sara Bobisse, Mariastella de Tiani, Hui Song Pak

Sci Adv· June 2025

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A Cluster of Evolutionarily Recent KRAB Zinc Finger Proteins Protects Cancer Cells from Replicative Stress-Induced Inflammation.
Filipe Martins, Olga Rosspopoff, Joana Carlevaro-Fita, Romain Forey, Sandra Offner, HuiSong Pak

Cancer Res· March 2024

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Immunopeptidomics-based identification of naturally presented non-canonical circRNA-derived peptides.
Humberto J Ferreira, Brian J Stevenson, HuiSong Pak, Fengchao Yu, Jessica Almeida Oliveira

Nat Commun· March 2024

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HIV vaccines induce CD8 T cells with low antigen receptor sensitivity.
Stephen A Migueles, Danielle M Nettere, Noah V Gavil, Lawrence T Wang, Sushila A Toulmin, HuiSong Pak

Science· December 2023

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A microfluidics-enabled automated workflow of sample preparation for MS-based immunopeptidomics.
Xiaokang Li, Hui Song Pak, Florian Huber, Justine Michaux, Marie Taillandier-Coindard

Cell Rep Methods· June 2023

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The immunopeptidome landscape associated with T cell infiltration, inflammation and immune editing in lung cancer.
Anne I Kraemer, Chloe Chong, Florian Huber, HuiSong Pak, Brian J Stevenson

Nat Cancer· May 2023

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Author Correction: Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.
Abhijeet Pataskar, Julien Champagne, Remco Nagel, Juliana Kenski, Maarja Laos, Hui Song Pak

Nature· August 2022

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CIITA-Transduced Glioblastoma Cells Uncover a Rich Repertoire of Clinically Relevant Tumor-Associated HLA-II Antigens.
Greta Forlani, Justine Michaux, HuiSong Pak, Florian Huber, Elodie Lauret Marie Joseph

Mol Cell Proteomics· March 2022

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Sensitive Immunopeptidomics by Leveraging Available Large-Scale Multi-HLA Spectral Libraries, Data-Independent Acquisition, and MS/MS Prediction.
HuiSong Pak, Justine Michaux, Florian Huber, Chloe Chong, Brian J Stevenson

Mol Cell Proteomics· March 2022

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Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.
Abhijeet Pataskar, Julien Champagne, Remco Nagel, Juliana Kenski, Maarja Laos, Hui Song Pak

Nature· March 2022

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Bedside formulation of a personalized multi-neoantigen vaccine against mammary carcinoma.
Mona O Mohsen, Daniel E Speiser, Justine Michaux, HuiSong Pak, Brian J Stevenson

J Immunother Cancer· January 2022

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Reversion analysis reveals the in vivo immunogenicity of a poorly MHC I-binding cancer neoepitope.
Hakimeh Ebrahimi-Nik, Marmar Moussa, Ryan P Englander, Summit Singhaviranon, Justine Michaux, HuiSong Pak

Nat Commun· November 2021

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Biogenesis of HLA Ligand Presentation in Immune Cells Upon Activation Reveals Changes in Peptide Length Preference.
Fabio Marino, Aikaterini Semilietof, Justine Michaux, Hui-Song Pak, George Coukos

Front Immunol· April 2021

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A Phase Ib Study of the Combination of Personalized Autologous Dendritic Cell Vaccine, Aspirin, and Standard of Care Adjuvant Chemotherapy Followed by Nivolumab for Resected Pancreatic Adenocarcinoma-A Proof of Antigen Discovery Feasibility in Three Patients.
Michal Bassani-Sternberg, Antonia Digklia, Florian Huber, Dorothea Wagner, Christine Sempoux, HuiSong Pak

Front Immunol· October 2020

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Rapid tumor vaccine using Toll-like receptor-activated ovarian cancer ascites monocytes.
Sarah F Adams, Alizée J Grimm, Cheryl L-L Chiang, Ananda Mookerjee, Dallas Flies, HuiSong Pak

J Immunother Cancer· August 2020

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Deciphering the Mechanisms of Improved Immunogenicity of Hypochlorous Acid-Treated Antigens in Anti-Cancer Dendritic Cell-Based Vaccines.
Michele Graciotti, Fabio Marino, HuiSong Pak, Petra Baumgaertner, Anne-Christine Thierry

Vaccines (Basel)· June 2020

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Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes.
Chloe Chong, Markus Müller, HuiSong Pak, Dermot Harnett, Florian Huber

Nat Commun· March 2020

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Mass Spectrometry Based Immunopeptidomics Leads to Robust Predictions of Phosphorylated HLA Class I Ligands.
Marthe Solleder, Philippe Guillaume, Julien Racle, Justine Michaux, Hui-Song Pak

Mol Cell Proteomics· February 2020

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Immunopeptidomics of colorectal cancer organoids reveals a sparse HLA class I neoantigen landscape and no increase in neoantigens with interferon or MEK-inhibitor treatment.
Alice Newey, Beatrice Griffiths, Justine Michaux, Hui Song Pak, Brian J Stevenson

J Immunother Cancer· November 2019

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Mass spectrometry driven exploration reveals nuances of neoepitope-driven tumor rejection.
Hakimeh Ebrahimi-Nik, Justine Michaux, William L Corwin, Grant Lj Keller, Tatiana Shcheglova, HuiSong Pak

JCI Insight· June 2019

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Estimating the Contribution of Proteasomal Spliced Peptides to the HLA-I Ligandome.
Roman Mylonas, Ilan Beer, Christian Iseli, Chloe Chong, Hui-Song Pak

Mol Cell Proteomics· December 2018

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The Length Distribution and Multiple Specificity of Naturally Presented HLA-I Ligands.
David Gfeller, Philippe Guillaume, Justine Michaux, Hui-Song Pak, Roy T Daniel

J Immunol· December 2018

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High-throughput and Sensitive Immunopeptidomics Platform Reveals Profound Interferonγ-Mediated Remodeling of the Human Leukocyte Antigen (HLA) Ligandome.
Chloe Chong, Fabio Marino, HuiSong Pak, Julien Racle, Roy T Daniel

Mol Cell Proteomics· March 2018

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Deciphering HLA-I motifs across HLA peptidomes improves neo-antigen predictions and identifies allostery regulating HLA specificity.
Michal Bassani-Sternberg, Chloé Chong, Philippe Guillaume, Marthe Solleder, HuiSong Pak

PLoS Comput Biol· August 2017

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