Publications by authors named "Hunter B Fraser"

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In silico genome transplants and the cis-regulatory basis of biodiversity.
Alexander L Starr, Michael E Palmer, Hunter B Fraser

Trends Genet· November 2025

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Massively parallel interrogation of the fitness of natural variants in ancient signaling pathways reveals pervasive local adaptation.
Jose Aguilar-Rodriguez, Jean C C Vila, Shi-An A Chen, Manuel Razo-Mejia, Olivia M Ghosh, Hunter B Fraser

bioRxiv· September 2025

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A General Principle of Neuronal Evolution Reveals a Human-Accelerated Neuron Type Potentially Underlying the High Prevalence of Autism in Humans.
Alexander L Starr, Hunter B Fraser

Mol Biol Evol· September 2025

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Disentangling cell-intrinsic and cell-extrinsic factors underlying evolution.
Alexander L Starr, Toshiya Nishimura, Kyomi J Igarashi, Chihiro Funamoto, Hiromitsu Nakauchi, Hunter B Fraser

Cell Genom· August 2025

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A general principle of neuronal evolution reveals a human-accelerated neuron type potentially underlying the high prevalence of autism in humans.
Alexander L Starr, Hunter B Fraser

bioRxiv· February 2025

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Disentangling cell-intrinsic and extrinsic factors underlying evolution.
Alexander L Starr, Toshiya Nishimura, Kyomi J Igarashi, Chihiro Funamoto, Hiromitsu Nakauchi, Hunter B Fraser

bioRxiv· August 2024

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Cell-type-specific -regulatory divergence in gene expression and chromatin accessibility revealed by human-chimpanzee hybrid cells.
Ban Wang, Alexander L Starr, Hunter B Fraser

Elife· February 2024

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Chromatin activity identifies differential gene regulation across human ancestries.
Kade P Pettie, Maxwell Mumbach, Amanda J Lea, Julien Ayroles, Howard Y Chang, Hunter B Fraser

Genome Biol· January 2024

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Allele-specific expression reveals genetic drivers of tissue regeneration in mice.
Katya L Mack, Heather E Talbott, Michelle F Griffin, Jennifer B L Parker, Nicholas J Guardino, Hunter B Fraser

Cell Stem Cell· October 2023

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Cell type-specific -regulatory divergence in gene expression and chromatin accessibility revealed by human-chimpanzee hybrid cells.
Ban Wang, Alexander L Starr, Hunter B Fraser

bioRxiv· September 2023

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Widespread epistasis among beneficial genetic variants revealed by high-throughput genome editing.
Roy Moh Lik Ang, Shi-An A Chen, Alexander F Kern, Yihua Xie, Hunter B Fraser

Cell Genom· April 2023

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Gene-by-environment interactions are pervasive among natural genetic variants.
Shi-An A Chen, Alexander F Kern, Roy Moh Lik Ang, Yihua Xie, Hunter B Fraser

Cell Genom· April 2023

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Evolution of Spatial and Temporal cis-Regulatory Divergence in Sticklebacks.
Katya L Mack, Tyler A Square, Bin Zhao, Craig T Miller, Hunter B Fraser

Mol Biol Evol· March 2023

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Accounting for cis-regulatory constraint prioritizes genes likely to affect species-specific traits.
Alexander L Starr, David Gokhman, Hunter B Fraser

Genome Biol· January 2023

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Existing methods are effective at measuring natural selection on gene expression.
Hunter B Fraser

Nat Ecol Evol· December 2022

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Transcriptome diversity is a systematic source of variation in RNA-sequencing data.
Pablo E García-Nieto, Ban Wang, Hunter B Fraser

PLoS Comput Biol· March 2022

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Bacterial Retrons Enable Precise Gene Editing in Human Cells.
Bin Zhao, Shi-An A Chen, Jiwoo Lee, Hunter B Fraser

CRISPR J· February 2022

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cis-Regulatory changes in locomotor genes are associated with the evolution of burrowing behavior.
Caroline K Hu, Ryan A York, Hillery C Metz, Nicole L Bedford, Hunter B Fraser

Cell Rep· February 2022

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Divergent patterns of selection on metabolite levels and gene expression.
Alexander F Kern, Grace Xiaolu Yang, Neil M Khosla, Roy Moh Lik Ang, Michael P Snyder, Hunter B Fraser

BMC Ecol Evol· September 2021

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GRINS: Genetic elements that recode assembly-line polyketide synthases and accelerate their diversification.
Aleksandra Nivina, Sur Herrera Paredes, Hunter B Fraser, Chaitan Khosla

Proc Natl Acad Sci U S A· June 2021

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Primate cell fusion disentangles gene regulatory divergence in neurodevelopment.
Rachel M Agoglia, Danqiong Sun, Fikri Birey, Se-Jin Yoon, Yuki Miura, Hunter B Fraser

Nature· April 2021

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Human-chimpanzee fused cells reveal cis-regulatory divergence underlying skeletal evolution.
David Gokhman, Rachel M Agoglia, Maia Kinnebrew, Wei Gordon, Danqiong Sun, Hunter B Fraser

Nat Genet· April 2021

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Publisher Correction: Human-chimpanzee fused cells reveal cis-regulatory divergence underlying skeletal evolution.
David Gokhman, Rachel M Agoglia, Maia Kinnebrew, Wei Gordon, Danqiong Sun, Hunter B Fraser

Nat Genet· April 2021

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The -regulatory effects of modern human-specific variants.
Carly V Weiss, Lana Harshman, Fumitaka Inoue, Hunter B Fraser, Dmitri A Petrov

Elife· April 2021

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Lineage-specific selection and the evolution of virulence in the clade.
Sheena D Singh-Babak, Tomas Babak, Hunter B Fraser, Alexander D Johnson

Proc Natl Acad Sci U S A· March 2021

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