Publications by authors named "Ian D Lewis"

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Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1, GATA2, and DDX41.
Claire C Homan, Michael W Drazer, Kai Yu, David M Lawrence, Jinghua Feng, Ian D Lewis

Blood Adv· October 2023

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Genome-wide transcription factor-binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs.
Shruthi Subramanian, Julie A I Thoms, Yizhou Huang, Paola Cornejo-Páramo, Forrest C Koch, Ian D Lewis

Blood· October 2023

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Author Correction: Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia.
Mahmoud A Bassal, Saumya E Samaraweera, Kelly Lim, Brooks A Benard, Sheree Bailey, Ian D Lewis

Nat Commun· July 2022

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Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia.
Mahmoud A Bassal, Saumya E Samaraweera, Kelly Lim, Brooks A Benard, Sheree Bailey, Ian D Lewis

Nat Commun· May 2022

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RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML.
Anna L Brown, Peer Arts, Catherine L Carmichael, Milena Babic, Julia Dobbins, Ian D Lewis

Blood Adv· March 2020

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Efficacy of combined CDK9/BET inhibition in preclinical models of MLL-rearranged acute leukemia.
Hannah McCalmont, Ka Leung Li, Luke Jones, John Toubia, Sarah C Bray, Ian D Lewis

Blood Adv· January 2020

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The mutational burden of therapy-related myeloid neoplasms is similar to primary myelodysplastic syndrome but has a distinctive distribution.
Deepak Singhal, Li Yan A Wee, Monika M Kutyna, Rakchha Chhetri, Joel Geoghegan, Ian D Lewis

Leukemia· December 2019

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A phase II study of a modified hyper-CVAD frontline therapy for patients with adverse risk diffuse large B-cell and peripheral T-cell non-Hodgkin lymphoma.
Greg Hapgood, Janey M Stone, Diana Zannino, Anup George, Paula Marlton, Ian D Lewis

Leuk Lymphoma· April 2019

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Genomic subtyping and therapeutic targeting of acute erythroleukemia.
Ilaria Iacobucci, Ji Wen, Manja Meggendorfer, John K Choi, Lei Shi, Ian D Lewis

Nat Genet· April 2019

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Red cell alloimmunization is associated with development of autoantibodies and increased red cell transfusion requirements in myelodysplastic syndrome.
Deepak Singhal, Monika M Kutyna, Rakchha Chhetri, Li Yan A Wee, Sophia Hague, Ian D Lewis

Haematologica· December 2017

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Prospective, Randomized, Double-Blind, Phase III Clinical Trial of Anti-T-Lymphocyte Globulin to Assess Impact on Chronic Graft-Versus-Host Disease-Free Survival in Patients Undergoing HLA-Matched Unrelated Myeloablative Hematopoietic Cell Transplantation.
Robert J Soiffer, Haesook T Kim, Joseph McGuirk, Mitchell E Horwitz, Laura Johnston, Ian D Lewis

J Clin Oncol· December 2017

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A Phase 2/3 Multicenter, Randomized, Open-Label Study to Compare the Efficacy and Safety of Lenalidomide Versus Investigator's Choice in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma.
Myron S Czuczman, Marek Trněný, Andrew Davies, Simon Rule, Kim M Linton, Ian D Lewis

Clin Cancer Res· August 2017

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Corrigendum to "KB004, a first in class monoclonal antibody targeting the receptor tyrosine kinase EphA3, in patients with advanced hematologic malignancies: Results from a phase 1 study" [Leuk. Res. 50 (Nov) (2016) 123-131. PubMed PMID: 27736729].
Ronan T Swords, Peter L Greenberg, Andrew H Wei, Simon Durrant, Anjali S Advani, Ian D Lewis

Leuk Res· August 2017

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Dynamic assessment of RBC-transfusion dependency improves the prognostic value of the revised-IPSS in MDS patients.
Devendra K Hiwase, Deepak Singhal, Corinna Strupp, Rakchha Chhetri, Monika M Kutyna, Ian D Lewis

Am J Hematol· June 2017

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Idarubicin Dose Escalation During Consolidation Therapy for Adult Acute Myeloid Leukemia.
Kenneth F Bradstock, Emma Link, Juliana Di Iulio, Jeff Szer, Paula Marlton, Ian D Lewis

J Clin Oncol· May 2017

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Erratum to "Filgrastim-Stimulated Bone Marrow Compared with Filgrastim-Mobilized Peripheral Blood in Myeloablative Sibling Allografting for Patients with Hematologic Malignancies: A Randomized Canadian Blood and Marrow Transplant Group Study" [Biol Blood Marrow Transplant 2016;22:1410-1415].
Stephen Couban, Mahmoud Aljurf, Sylvie Lachance, Irwin Walker, Cynthia Toze, Ian D Lewis

Biol Blood Marrow Transplant· March 2017

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Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia.
Jason A Powell, Alexander C Lewis, Wenying Zhu, John Toubia, Melissa R Pitman, Ian D Lewis

Blood· February 2017

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Early treatment intensification with R-ICE and 90Y-ibritumomab tiuxetan (Zevalin)-BEAM stem cell transplantation in patients with high-risk diffuse large B-cell lymphoma patients and positive interim PET after 4 cycles of R-CHOP-14.
Mark Hertzberg, Maher K Gandhi, Judith Trotman, Belinda Butcher, John Taper, Ian D Lewis

Haematologica· February 2017

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KB004, a first in class monoclonal antibody targeting the receptor tyrosine kinase EphA3, in patients with advanced hematologic malignancies: Results from a phase 1 study.
Ronan T Swords, Peter L Greenberg, Andrew H Wei, Simon Durrant, Anjali S Advani, Ian D Lewis

Leuk Res· November 2016

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Filgrastim-Stimulated Bone Marrow Compared with Filgrastim-Mobilized Peripheral Blood in Myeloablative Sibling Allografting for Patients with Hematologic Malignancies: A Randomized Canadian Blood and Marrow Transplant Group Study.
Stephen Couban, Mahmoud Aljurf, Sylvie Lachance, Irwin Walker, Cynthia Toze, Ian D Lewis

Biol Blood Marrow Transplant· August 2016

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Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.
Sheng Li, Francine E Garrett-Bakelman, Stephen S Chung, Mathijs A Sanders, Todd Hricik, Ian D Lewis

Nat Med· July 2016

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GD2-specific CAR T Cells Undergo Potent Activation and Deletion Following Antigen Encounter but can be Protected From Activation-induced Cell Death by PD-1 Blockade.
Tessa Gargett, Wenbo Yu, Gianpietro Dotti, Eric S Yvon, Susan N Christo, Ian D Lewis

Mol Ther· June 2016

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Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignancies.
Maya Lewinsohn, Anna L Brown, Luke M Weinel, Connie Phung, George Rafidi, Ian D Lewis

Blood· February 2016

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Efficacy of an Fc-modified anti-CD123 antibody (CSL362) combined with chemotherapy in xenograft models of acute myelogenous leukemia in immunodeficient mice.
Erwin M Lee, Dean Yee, Samantha J Busfield, Julie F McManus, Nik Cummings, Ian D Lewis

Haematologica· July 2015

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Vosaroxin is a novel topoisomerase-II inhibitor with efficacy in relapsed and refractory acute myeloid leukaemia.
Anya K Hotinski, Ian D Lewis, David M Ross

Expert Opin Pharmacother· June 2015

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