Publications by authors named "Jason A Powell"

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Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia.
Alexander C Lewis, Emily Gruber, Rheana Franich, Jessica Armstrong, Madison J Kelly, Jason A Powell

Cell· January 2026

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Sphingosine 1-phosphate signalling in cancer stem cells.
Jason A Powell, Stuart M Pitson

Oncogenesis· November 2025

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Venetoclax therapy and emerging resistance mechanisms in acute myeloid leukaemia.
Gus O Nwosu, David M Ross, Jason A Powell, Stuart M Pitson

Cell Death Dis· June 2024

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The 10 Barossa meeting: Cell Signalling to Cancer Medicine.
Winnie L Kan, Barbara J McClure, Christopher N Hahn, Jason A Powell

Cell Death Dis· March 2024

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An orthotopic syngeneic mouse model of bortezomib-resistant multiple myeloma.
Manjun Li, Melissa K Bennett, John Toubia, Victoria S Pope, Melinda N Tea, Jason A Powell

Br J Haematol· February 2024

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Genome-wide transcription factor-binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs.
Shruthi Subramanian, Julie A I Thoms, Yizhou Huang, Paola Cornejo-Páramo, Forrest C Koch, Jason A Powell

Blood· October 2023

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Circular RNAs drive oncogenic chromosomal translocations within the MLL recombinome in leukemia.
Vanessa M Conn, Marta Gabryelska, John Toubia, Kirsty Kirk, Laura Gantley, Jason A Powell

Cancer Cell· July 2023

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Targeting the integrated stress response in hematologic malignancies.
Gus O Nwosu, Jason A Powell, Stuart M Pitson

Exp Hematol Oncol· November 2022

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Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia.
Alexander C Lewis, Victoria S Pope, Melinda N Tea, Manjun Li, Gus O Nwosu, Jason A Powell

Blood· June 2022

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Resensitising proteasome inhibitor-resistant myeloma with sphingosine kinase 2 inhibition.
Melissa K Bennett, Manjun Li, Melinda N Tea, Melissa R Pitman, John Toubia, Jason A Powell

Neoplasia· January 2022

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The sphingosine 1-phosphate receptor 2/4 antagonist JTE-013 elicits off-target effects on sphingolipid metabolism.
Melissa R Pitman, Alexander C Lewis, Lorena T Davies, Paul A B Moretti, Dovile Anderson, Jason A Powell

Sci Rep· January 2022

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Author Correction: Targeting sphingolipid metabolism as an approach for combination therapies in haematological malignancies.
Alexander C Lewis, Craig T Wallington-Beddoe, Jason A Powell, Stuart M Pitson

Cell Death Discov· June 2021

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Clinical MDR1 inhibitors enhance Smac-mimetic bioavailability to kill murine LSCs and improve survival in AML models.
Emma Morrish, Anthony Copeland, Donia M Moujalled, Jason A Powell, Natasha Silke

Blood Adv· October 2020

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MRI of the Wrist: Algorithmic Approach for Evaluating Wrist Pain.
Greg S Matthews, Bahram Kiani, Scott D Wuertzer, Jason A Powell, Brandon L Roller

Radiographics· March 2020

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Kelch-like protein 5-mediated ubiquitination of lysine 183 promotes proteasomal degradation of sphingosine kinase 1.
Jason A Powell, Melissa R Pitman, Julia R Zebol, Paul A B Moretti, Heidi A Neubauer

Biochem J· November 2019

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Identification of sphingosine kinase 1 as a therapeutic target in B-lineage acute lymphoblastic leukaemia.
Craig T Wallington-Beddoe, Vicki Xie, Daochen Tong, Jason A Powell, Alexander C Lewis

Br J Haematol· February 2019

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Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma.
Heidi A Neubauer, Melinda N Tea, Julia R Zebol, Briony L Gliddon, Cassandra Stefanidis, Jason A Powell

Oncogene· February 2019

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Modification of the tumour microenvironment exosomal shedding of sphingosine 1-phosphate receptor 2 by breast cancer cells.
Stuart M Pitson, Jason A Powell

Oncotarget· July 2018

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Targeting sphingolipid metabolism as an approach for combination therapies in haematological malignancies.
Alexander C Lewis, Craig T Wallington-Beddoe, Jason A Powell, Stuart M Pitson

Cell Death Discov· June 2018

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Forensic Radiology Pitfalls: CT Imaging in Gunshot Wounds of the Head.
Mark A Giffen, Jason A Powell, Jerri McLemore

J Forensic Sci· March 2018

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Targeting sphingosine kinase 1 in acute myeloid leukemia: translation to clinic.
Jason A Powell, Craig T Wallington-Beddoe, Stuart M Pitson

Int J Hematol Oncol· June 2017

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Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population.
Nadine Hein, Donald P Cameron, Katherine M Hannan, Nhu-Y N Nguyen, Chun Yew Fong, Jason A Powell

Blood· May 2017

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Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia.
Jason A Powell, Alexander C Lewis, Wenying Zhu, John Toubia, Melissa R Pitman

Blood· February 2017

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An oncogenic role for sphingosine kinase 2.
Heidi A Neubauer, Duyen H Pham, Julia R Zebol, Paul A B Moretti, Amanda L Peterson, Jason A Powell

Oncotarget· October 2016

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Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors.
Amanda M Smith, Matthew D Dun, Erwin M Lee, Celeste Harrison, Richard Kahl, Jason A Powell

Oncotarget· July 2016

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