Publications by authors named "Ian Street"

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Catalytic Inhibition of KAT6/KAT7 Enhances the Efficacy and Overcomes Primary and Acquired Resistance to Menin Inhibitors in MLL Leukemia.
Shellaina J V Gordon, Florian Perner, Laura MacPherson, Katie A Fennell, Daniela V Wenge, Ian P Street

Cancer Discov· October 2025

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The Super Enhancer-Driven Long Noncoding RNA PRKCQ-AS1 Promotes Neuroblastoma Tumorigenesis by Interacting With MSI2 Protein and Is Targetable by Small Molecule Compounds.
Sujanna Mondal, Pei Y Liu, Janith Seneviratne, Antoine De Weck, Pooja Venkat, Ian Street

Adv Sci (Weinh)· May 2025

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The Significance of the 'Insignificant': Non-covalent Interactions in CO Reduction Reactions with 3C-TM (TM=Sc-Zn) Single-Atom Catalysts.
Linguo Lu, Jingsong Huang, Alvaro Guerrero, Ian Street, Sriram Mosali

ChemSusChem· March 2025

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Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia.
Shellaina J V Gordon, Florian Perner, Laura MacPherson, Daniela V Wenge, Wallace Bourgeois, Ian P Street

bioRxiv· December 2024

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Developing an accurately sized tonsil tie simulator: a prospective, observational study to measure the anatomical distance from the incisor teeth to the inferior tonsillar pole in a paediatric population.
Aikaterini Eleftheriadou, Addison Taylor, Madhankumar Krishnan, Ian Street

J Laryngol Otol· October 2024

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BMP4-Induced Suppression of Breast Cancer Metastasis Is Associated with Inhibition of Cholesterol Biosynthesis.
Lap Hing Chi, Andrew D Redfern, Terry C C Lim Kam Sian, Ian P Street, Allan D Burrows

Int J Mol Sci· August 2024

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Loss of tumor-derived SMAD4 enhances primary tumor growth but not metastasis following BMP4 signalling.
Lap Hing Chi, Andrew D Redfern, Suraya Roslan, Ian P Street, Allan D Burrows

Cell Commun Signal· April 2024

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BNC210, a negative allosteric modulator of the alpha 7 nicotinic acetylcholine receptor, demonstrates anxiolytic- and antidepressant-like effects in rodents.
Susan M O'Connor, Brad E Sleebs, Ian P Street, Bernard L Flynn, Jonathan B Baell

Neuropharmacology· March 2024

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Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer.
Shikhar Sharma, Chi-Yeh Chung, Sean Uryu, Jelena Petrovic, Joan Cao, Ian P Street

Cell Chem Biol· October 2023

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Bullying-induced dyspnea in children: A case series.
Ian P Sinha, Claire Hepworth, Sujata De, Sunil D Sharma, Ian Street

Pediatr Pulmonol· September 2021

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Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors.
Christoph Grohmann, Francesca Walker, Mark Devlin, Meng-Xiao Luo, Anderly C Chüeh, Ian Street

Cell Death Dis· March 2021

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Temporal Analysis of Brd4 Displacement in the Control of B Cell Survival, Proliferation, and Differentiation.
Isabella Y Kong, Joel S Rimes, Amanda Light, Izabela Todorovski, Sarah Jones, Ian P Street

Cell Rep· October 2020

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Discovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents.
Daniel L Priebbenow, David J Leaver, Nghi Nguyen, Benjamin Cleary, H Rachel Lagiakos, Ian P Street

J Med Chem· May 2020

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HBO1 is required for the maintenance of leukaemia stem cells.
Laura MacPherson, Juliana Anokye, Miriam M Yeung, Enid Y N Lam, Yih-Chih Chan, Ian P Street

Nature· January 2020

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Fragment screening for a protein-protein interaction inhibitor to WDR5.
Matthew L Dennis, Benjamin J Morrow, Olan Dolezal, Anthony N Cuzzupe, Alexandra E Stupple, Ian P Street

Struct Dyn· November 2019

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Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma.
Shatha AbuHammad, Carleen Cullinane, Claire Martin, Zoe Bacolas, Teresa Ward, Ian Street

Proc Natl Acad Sci U S A· September 2019

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Discovery of Benzoylsulfonohydrazides as Potent Inhibitors of the Histone Acetyltransferase KAT6A.
David J Leaver, Benjamin Cleary, Nghi Nguyen, Daniel L Priebbenow, H Rachel Lagiakos, Ian P Street

J Med Chem· August 2019

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Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors.
Anuratha Sakthianandeswaren, Marie J Parsons, Dmitri Mouradov, Ruth N MacKinnon, Bruno Catimel, Ian Street

Cancer Discov· August 2018

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Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
Jonathan B Baell, David J Leaver, Stefan J Hermans, Gemma L Kelly, Margs S Brennan, Ian P Street

Nature· August 2018

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Hoarseness in children.
Salil Sood, Ian Street, Adam Donne

Br J Hosp Med (Lond)· December 2017

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Sunshine outside the ivory tower.
Amanda Welch, Cleyde Helena, Ian Street

Science· September 2017

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Cytokinin induces genome-wide binding of the type-B response regulator ARR10 to regulate growth and development in .
Yan O Zubo, Ivory Clabaugh Blakley, Maria V Yamburenko, Jennifer M Worthen, Ian H Street

Proc Natl Acad Sci U S A· July 2017

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Facilitating conservation.
Prosanta Chakrabarty, Swati Negi, Rigoberto Medina Andrés, Brett Favaro, Bipin Singh, Ian H Street

Science· April 2017

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Cytokinin acts through the auxin influx carrier AUX1 to regulate cell elongation in the root.
Ian H Street, Dennis E Mathews, Maria V Yamburkenko, Ali Sorooshzadeh, Roshen T John

Development· November 2016

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Ethylene Inhibits Cell Proliferation of the Arabidopsis Root Meristem.
Ian H Street, Sitwat Aman, Yan Zubo, Aleena Ramzan, Xiaomin Wang

Plant Physiol· September 2015

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