Publications by authors named "Francesca Walker"

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Dual drug targeting to kill colon cancers.
Silvia Paola Corona, Francesca Walker, Janet Weinstock, Guillaume Lessene, Maree Faux

Cancer Med· July 2022

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Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors.
Christoph Grohmann, Francesca Walker, Mark Devlin, Meng-Xiao Luo, Anderly C Chüeh

Cell Death Dis· March 2021

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Characterization of Toxin Complex Gene Clusters and Insect Toxicity of Bacteria Representing Four Subgroups of Pseudomonas fluorescens.
Lorena I Rangel, Marcella D Henkels, Brenda T Shaffer, Francesca L Walker, Edward W Davis

PLoS One· July 2017

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Rhizoxin analogs, orfamide A and chitinase production contribute to the toxicity of Pseudomonas protegens strain Pf-5 to Drosophila melanogaster.
Joyce E Loper, Marcella D Henkels, Lorena I Rangel, Marika H Olcott, Francesca L Walker

Environ Microbiol· October 2016

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LRIG1 extracellular domain: structure and function analysis.
Yibin Xu, Priscilla Soo, Francesca Walker, Hui Hua Zhang, Nicholas Redpath

J Mol Biol· May 2015

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CDC42 inhibition suppresses progression of incipient intestinal tumors.
Ryotaro Sakamori, Shiyan Yu, Xiao Zhang, Andrew Hoffman, Jiaxin Sun, Francesca Walker

Cancer Res· October 2014

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Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration.
Toby J Phesse, Michael Buchert, Emma Stuart, Dustin J Flanagan, Maree Faux, Francesca Walker

Sci Signal· September 2014

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Ligand binding induces a conformational change in epidermal growth factor receptor dimers.
Francesca Walker, Julie Rothacker, Christine Henderson, Edouard C Nice, Bruno Catimel

Growth Factors· December 2012

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LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines.
Francesca Walker, Hui-Hua Zhang, Annalisa Odorizzi, Antony W Burgess

PLoS One· December 2011

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PHLDA1 expression marks the putative epithelial stem cells and contributes to intestinal tumorigenesis.
Anuratha Sakthianandeswaren, Michael Christie, Carla D'Andreti, Cary Tsui, Robert N Jorissen, Francesca Walker

Cancer Res· May 2011

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Nonsense mediated decay resistant mutations are a source of expressed mutant proteins in colon cancer cell lines with microsatellite instability.
David S Williams, Matthew J Bird, Robert N Jorissen, Yen Lin Yu, Francesca Walker

PLoS One· December 2010

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Lethality and developmental delay in Drosophila melanogaster larvae after ingestion of selected Pseudomonas fluorescens strains.
Marika H Olcott, Marcella D Henkels, Kise L Rosen, Francesca L Walker, Baruch Sneh

PLoS One· September 2010

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Selective inhibition of proliferation in colorectal carcinoma cell lines expressing mutant APC or activated B-Raf.
Hui-Hua Zhang, Francesca Walker, Sara Kiflemariam, Robert H Whitehead, David Williams

Int J Cancer· July 2009

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Antibodies specifically targeting a locally misfolded region of tumor associated EGFR.
Thomas P J Garrett, Antony W Burgess, Hui K Gan, Rod B Luwor, Glenn Cartwright, Francesca Walker

Proc Natl Acad Sci U S A· March 2009

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IL6/sIL6R complex contributes to emergency granulopoietic responses in G-CSF- and GM-CSF-deficient mice.
Francesca Walker, Hui-Hua Zhang, Vance Matthews, Janet Weinstock, Edouard C Nice

Blood· April 2008

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Macrophage-colony stimulating factor is required for the production of neutrophil-promoting activity by mouse embryo fibroblasts deficient in G-CSF and GM-CSF.
Hui Hua Zhang, Sunanda Basu, Fenqiang Wu, C Glenn Begley, Christiaan J M Saris, Francesca Walker

J Leukoc Biol· October 2007

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The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor AG1478 increases the formation of inactive untethered EGFR dimers. Implications for combination therapy with monoclonal antibody 806.
Hui K Gan, Francesca Walker, Antony W Burgess, Angela Rigopoulos, Andrew M Scott

J Biol Chem· February 2007

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Identification of a novel EGF-sensitive cell cycle checkpoint.
Francesca Walker, Hui-Hua Zhang, Antony W Burgess

Exp Cell Res· February 2007

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Functional effects of glycosylation at Asn-579 of the epidermal growth factor receptor.
Kristin B Whitson, Stefanie R Whitson, Monica L Red-Brewer, Austin J McCoy, Angela A Vitali, Francesca Walker

Biochemistry· November 2005

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Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis.
Andrew H A Clayton, Francesca Walker, Suzanne G Orchard, Christine Henderson, Dominik Fuchs

J Biol Chem· August 2005

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The role of disulfide bonds in the structure and function of murine epidermal growth factor (mEGF).
Dianne Alewood, Kathy Nielsen, Paul F Alewood, David J Craik, Peter Andrews, Francesca Walker

Growth Factors· June 2005

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Cortactin overexpression inhibits ligand-induced down-regulation of the epidermal growth factor receptor.
Paul Timpson, Danielle K Lynch, Daniel Schramek, Francesca Walker, Roger J Daly

Cancer Res· April 2005

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Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling.
Sandra E Nicholson, Donald Metcalf, Naomi S Sprigg, Ruth Columbus, Francesca Walker

Proc Natl Acad Sci U S A· February 2005

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The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR.
Rodney B Luwor, Hong-Jian Zhu, Francesca Walker, Angela A Vitali, Rushika M Perera

Oncogene· August 2004

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Identification of the epitope for the epidermal growth factor receptor-specific monoclonal antibody 806 reveals that it preferentially recognizes an untethered form of the receptor.
Terrance G Johns, Timothy E Adams, Jennifer R Cochran, Nathan E Hall, Peter A Hoyne, Francesca Walker

J Biol Chem· July 2004

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