Publications by authors named "Ibrahim Ince"

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A novel transformer using dynamic range-enhanced discrete cosine transform for detecting bean leaf diseases.
Ibrahim Furkan Ince, Harisu Abdullahi Shehu, Shaira Osmani, Faruk Bulut

Front Plant Sci· September 2025

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Harnessing Open-Source Solutions: Insights From the First Open Systems Pharmacology (OSP) Community Conference.
André Dallmann, Denise Feick, Pavel Balazki, Salih Benamara, Rolf Burghaus, Ibrahim Ince

CPT Pharmacometrics Syst Pharmacol· May 2025

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Assessing Drug-Drug Interaction and Food Effect for BCS Class 2 Compound BI 730357 (Retinoic Acid-Related Orphan Receptor Gamma Antagonist, Bevurogant) Using a Physiology-Based Pharmacokinetics Modeling (PBPK) Approach with Semi-Mechanistic Absorption.
Tobias Kanacher, Erik Sjögren, Julia Korell, Elodie L Plan, Jose David Gómez-Mantilla, Ibrahim Ince

Pharmaceutics· March 2025

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Applied physiologically-based pharmacokinetic modeling to assess uridine diphosphate-glucuronosyltransferase-mediated drug-drug interactions for Vericiguat.
Sebastian Frechen, Ibrahim Ince, André Dallmann, Michael Gerisch, Natalia A Jungmann

CPT Pharmacometrics Syst Pharmacol· January 2024

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Physiologically based pharmacokinetic (PBPK) modelling of oral drug absorption in older adults - an AGePOP review.
Cleo Demeester, Donnia Robins, Angela Elma Edwina, Jos Tournoy, Patrick Augustijns, Ibrahim Ince

Eur J Pharm Sci· September 2023

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Population Pharmacokinetics of Nifurtimox in Adult and Pediatric Patients With Chagas Disease.
Ibrahim Ince, Klaas Prins, Stefan Willmann, Gabriele Sutter, Eva Hanze

J Clin Pharmacol· October 2022

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Classification of Breast Cancer Histopathological Images Using DenseNet and Transfer Learning.
Musa Adamu Wakili, Harisu Abdullahi Shehu, Md Haidar Sharif, Md Haris Uddin Sharif, Abubakar Umar, Ibrahim Furkan Ince

Comput Intell Neurosci· October 2022

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Model-informed bridging of rivaroxaban doses for thromboprophylaxis in pediatric patients aged 9 years and older with congenital heart disease.
Stefan Willmann, Ibrahim Ince, Maurice Ahsman, Katrin Coboeken, Yang Zhang

CPT Pharmacometrics Syst Pharmacol· August 2022

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Nifurtimox for Treatment of Chagas Disease in Pediatric Patients: the Challenges of Applying Pharmacokinetic-Pharmacodynamic Principles to Dose Finding.
Heino Stass, Ibrahim Ince, Ulrike Grossmann, Boris Weimann, Stefan Willmann

AAPS J· August 2022

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Clinical investigation of the biopharmaceutical characteristics of nifurtimox tablets - Implications for quality control and application.
Heino Stass, Sarah Just, Boris Weimann, Ibrahim Ince, Stefan Willmann

Eur J Pharm Sci· November 2021

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Population pharmacokinetic analysis of rivaroxaban in children and comparison to prospective physiologically-based pharmacokinetic predictions.
Stefan Willmann, Katrin Coboeken, Yang Zhang, Hannah Mayer, Ibrahim Ince

CPT Pharmacometrics Syst Pharmacol· October 2021

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A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactions.
Sebastian Frechen, Juri Solodenko, Thomas Wendl, André Dallmann, Ibrahim Ince

CPT Pharmacometrics Syst Pharmacol· June 2021

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Predictive Performance of Physiology-Based Pharmacokinetic Dose Estimates for Pediatric Trials: Evaluation With 10 Bayer Small-Molecule Compounds in Children.
Ibrahim Ince, André Dallmann, Sebastian Frechen, Katrin Coboeken, Christoph Niederalt

J Clin Pharmacol· June 2021

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Integration of physiological changes during the postpartum period into a PBPK framework and prediction of amoxicillin disposition before and shortly after delivery.
André Dallmann, Anneke Himstedt, Juri Solodenko, Ibrahim Ince, Georg Hempel

J Pharmacokinet Pharmacodyn· August 2020

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Predictive Pediatric Modeling and Simulation Using Ontogeny Information.
Ibrahim Ince, Juri Solodenko, Sebastian Frechen, André Dallmann, Christoph Niederalt

J Clin Pharmacol· September 2019

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Applied Concepts in PBPK Modeling: How to Extend an Open Systems Pharmacology Model to the Special Population of Pregnant Women.
André Dallmann, Juri Solodenko, Ibrahim Ince, Thomas Eissing

CPT Pharmacometrics Syst Pharmacol· July 2018

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A Physiologically Based Pharmacokinetic Model for Pregnant Women to Predict the Pharmacokinetics of Drugs Metabolized Via Several Enzymatic Pathways.
André Dallmann, Ibrahim Ince, Katrin Coboeken, Thomas Eissing, Georg Hempel

Clin Pharmacokinet· June 2018

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Physiologically Based Pharmacokinetic Modeling of Renally Cleared Drugs in Pregnant Women.
André Dallmann, Ibrahim Ince, Juri Solodenko, Michaela Meyer, Stefan Willmann

Clin Pharmacokinet· December 2017

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Gestation-Specific Changes in the Anatomy and Physiology of Healthy Pregnant Women: An Extended Repository of Model Parameters for Physiologically Based Pharmacokinetic Modeling in Pregnancy.
André Dallmann, Ibrahim Ince, Michaela Meyer, Stefan Willmann, Thomas Eissing

Clin Pharmacokinet· November 2017

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Developing a mobile application to better inform patients and enable effective consultation in implant dentistry.
Erokan Canbazoglu, Yucel Batu Salman, Mustafa Eren Yildirim, Burak Merdenyan, Ibrahim Furkan Ince

Comput Struct Biotechnol J· July 2016

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Evaluation of changes in oral drug absorption in preterm and term neonates for Biopharmaceutics Classification System (BCS) class I and II compounds.
Amit A Somani, Kirstin Thelen, Songmao Zheng, Mirjam N Trame, Katrin Coboeken, Ibrahim Ince

Br J Clin Pharmacol· January 2016

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A novel maturation function for clearance of the cytochrome P450 3A substrate midazolam from preterm neonates to adults.
Ibrahim Ince, Saskia N de Wildt, Chenguang Wang, Mariska Y M Peeters, Jacobus Burggraaf

Clin Pharmacokinet· July 2013

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Developmental changes in the expression and function of cytochrome P450 3A isoforms: evidence from in vitro and in vivo investigations.
Ibrahim Ince, Catherijne A J Knibbe, Meindert Danhof, Saskia N de Wildt

Clin Pharmacokinet· May 2013

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Critical illness is a major determinant of midazolam clearance in children aged 1 month to 17 years.
Ibrahim Ince, Saskia N de Wildt, Mariska Y M Peeters, Daryl J Murry, Dick Tibboel

Ther Drug Monit· August 2012

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Tailor-made drug treatment for children: creation of an infrastructure for data-sharing and population PK-PD modeling.
Ibrahim Ince, Saskia N de Wildt, Dick Tibboel, Meindert Danhof, Catherijne A J Knibbe

Drug Discov Today· March 2009

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