Publications by authors named "Juri Solodenko"

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An Open-Source Framework for Virtual Bioequivalence Modeling and Clinical Trial Design.
Abdullah Hamadeh, Moriah Pellowe, Pierre Chelle, Cindy Hoi Ting Yeung, Julian Otalvaro, Juri Solodenko

CPT Pharmacometrics Syst Pharmacol· December 2025

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Development of a novel physiologically based biopharmaceutics modeling (PBBM) framework using the open systems pharmacology suite, part 1: in vitro modeling of vericiguat.
Paul Vrenken, Maria Vertzoni, Sebastian Frechen, Juri Solodenko, Michaela Meyer

Eur J Pharm Sci· September 2025

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Development of a novel physiologically based biopharmaceutics modeling (PBBM) framework using the open systems pharmacology suite, part 2: in vivo pharmacokinetic modeling of vericiguat.
Paul Vrenken, Maria Vertzoni, Sebastian Frechen, Juri Solodenko, Michaela Meyer

Eur J Pharm Sci· September 2025

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A Comprehensive CYP2D6 Drug-Drug-Gene Interaction Network for Application in Precision Dosing and Drug Development.
Simeon Rüdesheim, Helena Leonie Hanae Loer, Denise Feick, Fatima Zahra Marok, Laura Maria Fuhr, Juri Solodenko

Clin Pharmacol Ther· June 2025

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Harnessing Open-Source Solutions: Insights From the First Open Systems Pharmacology (OSP) Community Conference.
André Dallmann, Denise Feick, Pavel Balazki, Salih Benamara, Rolf Burghaus, Juri Solodenko

CPT Pharmacometrics Syst Pharmacol· May 2025

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A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactions.
Sebastian Frechen, Juri Solodenko, Thomas Wendl, André Dallmann, Ibrahim Ince

CPT Pharmacometrics Syst Pharmacol· June 2021

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Integration of physiological changes during the postpartum period into a PBPK framework and prediction of amoxicillin disposition before and shortly after delivery.
André Dallmann, Anneke Himstedt, Juri Solodenko, Ibrahim Ince, Georg Hempel

J Pharmacokinet Pharmacodyn· August 2020

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Open Systems Pharmacology Community-An Open Access, Open Source, Open Science Approach to Modeling and Simulation in Pharmaceutical Sciences.
Jörg Lippert, Rolf Burghaus, Andrea Edginton, Sebastian Frechen, Mats Karlsson, Juri Solodenko

CPT Pharmacometrics Syst Pharmacol· December 2019

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Predictive Pediatric Modeling and Simulation Using Ontogeny Information.
Ibrahim Ince, Juri Solodenko, Sebastian Frechen, André Dallmann, Christoph Niederalt

J Clin Pharmacol· September 2019

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Applied Concepts in PBPK Modeling: How to Extend an Open Systems Pharmacology Model to the Special Population of Pregnant Women.
André Dallmann, Juri Solodenko, Ibrahim Ince, Thomas Eissing

CPT Pharmacometrics Syst Pharmacol· July 2018

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A generic whole body physiologically based pharmacokinetic model for therapeutic proteins in PK-Sim.
Christoph Niederalt, Lars Kuepfer, Juri Solodenko, Thomas Eissing, Hans-Ulrich Siegmund

J Pharmacokinet Pharmacodyn· April 2018

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Physiologically Based Pharmacokinetic Modeling of Renally Cleared Drugs in Pregnant Women.
André Dallmann, Ibrahim Ince, Juri Solodenko, Michaela Meyer, Stefan Willmann

Clin Pharmacokinet· December 2017

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A computational systems biology software platform for multiscale modeling and simulation: integrating whole-body physiology, disease biology, and molecular reaction networks.
Thomas Eissing, Lars Kuepfer, Corina Becker, Michael Block, Katrin Coboeken, Juri Solodenko

Front Physiol· July 2011

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On transferring the grid technology to the biomedical community.
Yassene Mohammed, Ulrich Sax, Frank Dickmann, Joerg Lippert, Juri Solodenko

Stud Health Technol Inform· October 2010

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Development of a physiology-based whole-body population model for assessing the influence of individual variability on the pharmacokinetics of drugs.
Stefan Willmann, Karsten Höhn, Andrea Edginton, Michael Sevestre, Juri Solodenko

J Pharmacokinet Pharmacodyn· June 2007

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