Publications by authors named "Igor Feldman"

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T-cell Responses to Individualized Neoantigen Therapy mRNA-4157 (V940) Alone or in Combination with Pembrolizumab in the Phase 1 KEYNOTE-603 Study.
Justin F Gainor, Manish R Patel, Jeffrey S Weber, Martin Gutierrez, Julie E Bauman, Igor Feldman

Cancer Discov· November 2024

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Preclinical Efficacy of VTX-0811: A Humanized First-in-Class PSGL-1 mAb Targeting TAMs to Suppress Tumor Growth.
Tatiana Novobrantseva, Denise Manfra, Jessica Ritter, Maja Razlog, Brian O'Nuallain, Igor Feldman

Cancers (Basel)· August 2024

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Antibodies Targeting Human or Mouse VSIG4 Repolarize Tumor-Associated Macrophages Providing the Potential of Potent and Specific Clinical Anti-Tumor Response Induced across Multiple Cancer Types.
Stephen Sazinsky, Mohammad Zafari, Boris Klebanov, Jessica Ritter, Phuong A Nguyen, Igor Feldman

Int J Mol Sci· June 2024

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Individualised neoantigen therapy mRNA-4157 (V940) plus pembrolizumab versus pembrolizumab monotherapy in resected melanoma (KEYNOTE-942): a randomised, phase 2b study.
Jeffrey S Weber, Matteo S Carlino, Adnan Khattak, Tarek Meniawy, George Ansstas, Igor Feldman

Lancet· February 2024

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Macrophages - Controlling the Bifurcation Between Tumor Existence or Regression.
Tatiana Novobrantseva, Denise Manfra, Ani Nguyen, Igor Feldman

Adv Biol (Weinh)· October 2023

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PSGL-1 Blockade Induces Classical Activation of Human Tumor-associated Macrophages.
Kevin Kauffman, Denise Manfra, Dominika Nowakowska, Mohammad Zafari, Phuong A Nguyen, Igor Feldman

Cancer Res Commun· October 2023

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EZH2 Inhibition by Tazemetostat Results in Altered Dependency on B-cell Activation Signaling in DLBCL.
Dorothy Brach, Danielle Johnston-Blackwell, Allison Drew, Trupti Lingaraj, Vinny Motwani, Igor Feldman

Mol Cancer Ther· November 2017

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Selective Killing of SMARCA2- and SMARCA4-deficient Small Cell Carcinoma of the Ovary, Hypercalcemic Type Cells by Inhibition of EZH2: and Preclinical Models.
Elayne Chan-Penebre, Kelli Armstrong, Allison Drew, Alexandra R Grassian, Igor Feldman

Mol Cancer Ther· May 2017

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An Unbiased Oncology Compound Screen to Identify Novel Combination Strategies.
Jennifer O'Neil, Yair Benita, Igor Feldman, Melissa Chenard, Brian Roberts

Mol Cancer Ther· June 2016

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Preclinical evaluation of the WEE1 inhibitor MK-1775 as single-agent anticancer therapy.
Amy D Guertin, Jing Li, Yaping Liu, Melissa S Hurd, Alwin G Schuller, Igor Feldman

Mol Cancer Ther· August 2013

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Unique functions of CHK1 and WEE1 underlie synergistic anti-tumor activity upon pharmacologic inhibition.
Amy D Guertin, Melissa M Martin, Brian Roberts, Melissa Hurd, Xianlu Qu, Igor Feldman

Cancer Cell Int· November 2012

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Pathway-based identification of biomarkers for targeted therapeutics: personalized oncology with PI3K pathway inhibitors.
Jannik N Andersen, Sriram Sathyanarayanan, Alessandra Di Bacco, An Chi, Theresa Zhang, Igor Feldman

Sci Transl Med· August 2010

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A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors.
Andrey Loboda, Michael Nebozhyn, Rich Klinghoffer, Jason Frazier, Michael Chastain, Igor Feldman

BMC Med Genomics· June 2010

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Network properties of genes harboring inherited disease mutations.
Igor Feldman, Andrey Rzhetsky, Dennis Vitkup

Proc Natl Acad Sci U S A· March 2008

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Dopamine presynaptically and heterogeneously modulates nucleus accumbens medium-spiny neuron GABA synapses in vitro.
Daron Geldwert, J Madison Norris, Igor G Feldman, Joshua J Schulman, Myra P Joyce

BMC Neurosci· June 2006

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