Publications by authors named "Ilka Mathar"

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Activating soluble guanylyl cyclase attenuates ischemic kidney damage.
Falk-Bach Lichtenberger, Minze Xu, Cem Erdoğan, Lingyan Fei, Ilka Mathar

Kidney Int· March 2025

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Runcaciguat activates soluble guanylyl cyclase via the histidine essential for heme binding and nitric oxide activation.
Theresa Wittrien, Anne Rühle, Christin Elgert, Ilka Mathar, Peter Sandner

Biochem Pharmacol· February 2025

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TRPC5 controls the adrenaline-mediated counter regulation of hypoglycemia.
Jenny Bröker-Lai, José Rego Terol, Christin Richter, Ilka Mathar, Angela Wirth

EMBO J· December 2024

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OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage.
Volodymyr Tsvilovskyy, Roger Ottenheijm, Ulrich Kriebs, Aline Schütz, Kalliope Nina Diakopoulos, Ilka Mathar

J Clin Invest· April 2024

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The sGC Activator Runcaciguat Has Kidney Protective Effects and Prevents a Decline of Kidney Function in ZSF1 Rats.
Jan R Kraehling, Agnes Benardeau, Tibor Schomber, Laura Popp, Julia Vienenkoetter, Ilka Mathar

Int J Mol Sci· August 2023

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Treatment effects of soluble guanylate cyclase modulation on diabetic kidney disease at single-cell resolution.
Michael S Balzer, Mira Pavkovic, Julia Frederick, Amin Abedini, Alexius Freyberger, Ilka Mathar

Cell Rep Med· April 2023

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Urinary miRNA Profiles in Chronic Kidney Injury-Benefits of Extracellular Vesicle Enrichment and miRNAs as Potential Biomarkers for Renal Fibrosis, Glomerular Injury, and Endothelial Dysfunction.
Barbara Petzuch, Agnès Bénardeau, Lucas Hofmeister, Jutta Meyer, Elke Hartmann, Ilka Mathar

Toxicol Sci· April 2022

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Effects of Finerenone Combined with Empagliflozin in a Model of Hypertension-Induced End-Organ Damage.
Peter Kolkhof, Elke Hartmann, Alexius Freyberger, Mira Pavkovic, Ilka Mathar

Am J Nephrol· February 2022

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Runcaciguat, a novel soluble guanylate cyclase activator, shows renoprotection in hypertensive, diabetic, and metabolic preclinical models of chronic kidney disease.
Agnès Bénardeau, Antje Kahnert, Tibor Schomber, Jutta Meyer, Mira Pavkovic, Ilka Mathar

Naunyn Schmiedebergs Arch Pharmacol· December 2021

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Assessing the Use of the sGC Stimulator BAY-747, as a Potential Treatment for Duchenne Muscular Dystrophy.
Shalini Murali Krishnan, Johannes Nordlohne, Lisa Dietz, Alexandros Vakalopoulos, Petra Haning, Ilka Mathar

Int J Mol Sci· July 2021

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Control of Insulin Release by Transient Receptor Potential Melastatin 3 (TRPM3) Ion Channels.
Alexander Becker, Stefanie Mannebach, Ilka Mathar, Petra Weissgerber, Marc Freichel

Cell Physiol Biochem· November 2020

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Loss of smooth muscle CYB5R3 amplifies angiotensin II-induced hypertension by increasing sGC heme oxidation.
Brittany G Durgin, Scott A Hahn, Heidi M Schmidt, Megan P Miller, Neha Hafeez, Ilka Mathar

JCI Insight· October 2019

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Methylglyoxal evokes acute Ca transients in distinct cell types and increases agonist-evoked Ca entry in endothelial cells via CRAC channels.
Robin Sachdeva, Thomas Fleming, Dagmar Schumacher, Sarah Homberg, Kathrin Stilz, Ilka Mathar

Cell Calcium· March 2019

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TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A.
Sin Ying Cheung, Matthias Henrot, Mohammad Al-Saad, Matthias Baumann, Heiko Muller, Ilka Mathar

Oncotarget· July 2018

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Nitric Oxide-Independent Soluble Guanylate Cyclase Activation Improves Vascular Function and Cardiac Remodeling in Sickle Cell Disease.
Karin P Potoka, Katherine C Wood, Jeffrey J Baust, Marta Bueno, Scott A Hahn, Ilka Mathar

Am J Respir Cell Mol Biol· May 2018

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TRPC proteins contribute to development of diabetic retinopathy and regulate glyoxalase 1 activity and methylglyoxal accumulation.
Robin Sachdeva, Andrea Schlotterer, Dagmar Schumacher, Christin Matka, Ilka Mathar

Mol Metab· March 2018

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New pulmonary hypertension model in conscious dogs to investigate pulmonary-selectivity of acute pharmacological interventions.
Thomas Mondritzki, Philip Boehme, Lena Schramm, Julia Vogel, Ilka Mathar

Eur J Appl Physiol· January 2018

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Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory.
Jenny Bröker-Lai, Astrid Kollewe, Barbara Schindeldecker, Jörg Pohle, Vivan Nguyen Chi, Ilka Mathar

EMBO J· September 2017

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TRPM4-mediated control of FcεRI-evoked Ca(2+) elevation comprises enhanced plasmalemmal trafficking of TRPM4 channels in connective tissue type mast cells.
Torben Rixecker, Ilka Mathar, Rebekka Medert, Stefanie Mannebach, Alexander Pfeifer

Sci Rep· September 2016

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A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling.
Juan E Camacho Londoño, Qinghai Tian, Karin Hammer, Laura Schröder, Julia Camacho Londoño, Ilka Mathar

Eur Heart J· September 2015

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Contractility Measurements on Isolated Papillary Muscles for the Investigation of Cardiac Inotropy in Mice.
Sebastian Uhl, Marc Freichel, Ilka Mathar

J Vis Exp· September 2015

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Adenylyl cyclase-mediated effects contribute to increased Isoprenaline-induced cardiac contractility in TRPM4-deficient mice.
Sebastian Uhl, Ilka Mathar, Rudi Vennekens, Marc Freichel

J Mol Cell Cardiol· September 2014

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TRPM4.
Ilka Mathar, Griet Jacobs, Miklos Kecskes, Aurelie Menigoz, Koenraad Philippaert

Handb Exp Pharmacol· July 2014

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Increased β-adrenergic inotropy in ventricular myocardium from Trpm4-/- mice.
Ilka Mathar, Miklos Kecskes, Gerry Van der Mieren, Griet Jacobs, Juan E Camacho Londoño

Circ Res· January 2014

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