Publications by authors named "Peter Sandner"

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Exploring the potential of soluble guanylyl cyclase stimulators and activators in heart failure.
Olga Gawrys, Petr Kala, Michal Šnorek, Vojtěch Melenovský, Stefano Corda, Peter Sandner

Biochem Pharmacol· December 2025

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Soluble guanylate cyclase stimulation improves cardiac function and mitochondrial activity in a rat model of early-stage heart failure with preserved ejection fraction.
Xocas Vázquez-Abuín, Sandra Moraña-Fernández, Alana Aragón-Herrera, Peter Sandner, Karen Thomitzek

Biomed Pharmacother· October 2025

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Discovery of the first isoform-specific sGC activator: Selective activation of GC-1 by runcaciguat.
Svenja Stomberg, Anne Rühle, Theresa Wittrien, Peter Sandner, Sönke Behrends

Eur J Pharmacol· June 2025

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The treatment with soluble guanylate cyclase stimulator BAY41-8543 prevents malignant hypertension and associated organ damage.
Martina Hüttl, Matúš Miklovič, Olga Gawryś, Matěj Molnár, Petra Škaroupková, Peter Sandner

J Hypertens· June 2025

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Effects of soluble guanylyl cyclase stimulation on muscle oxygenation and exercise capacity in heart failure with mildly reduced ejection fraction.
Ramona E Weber, Kiana M Schulze, Andrew G Horn, Tyler E McCoach, Zachary J White, Peter Sandner

Exp Physiol· June 2025

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Activating soluble guanylyl cyclase attenuates ischemic kidney damage.
Falk-Bach Lichtenberger, Minze Xu, Cem Erdoğan, Lingyan Fei, Ilka Mathar, Peter Sandner

Kidney Int· March 2025

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Runcaciguat activates soluble guanylyl cyclase via the histidine essential for heme binding and nitric oxide activation.
Theresa Wittrien, Anne Rühle, Christin Elgert, Ilka Mathar, Peter Sandner

Biochem Pharmacol· February 2025

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Soluble guanylyl cyclase stimulators and activators: Promising drugs for the treatment of hypertension?
Olga Gawrys, Petr Kala, Janusz Sadowski, Vojtěch Melenovský, Peter Sandner

Eur J Pharmacol· January 2025

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Biomarker analysis from the phase 2b randomized placebo-controlled trial of riociguat in early diffuse cutaneous systemic sclerosis.
Dinesh Khanna, Frank Kramer, Josef Höfler, Mercedeh Ghadessi, Peter Sandner

Rheumatology (Oxford)· November 2024

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The nitric oxide-soluble guanylate cyclase-cGMP pathway in pulmonary hypertension: from PDE5 to soluble guanylate cyclase.
Raymond L Benza, Ekkehard Grünig, Peter Sandner, Johannes-Peter Stasch, Gérald Simonneau

Eur Respir Rev· January 2024

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Soluble guanylyl cyclase: A novel target for the treatment of vascular cognitive impairment?
Ellis Nelissen, Melissa Schepers, Laura Ponsaerts, Sébastien Foulquier, Annelies Bronckaers, Peter Sandner

Pharmacol Res· November 2023

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Identification and characterization of the new generation soluble guanylate cyclase stimulator BAY-747 designed for the treatment of resistant hypertension.
Frank Wunder, Johannes-Peter Stasch, Andreas Knorr, Thomas Mondritzki, Damian Brockschnieder, Peter Sandner

Br J Pharmacol· October 2023

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The 10th International Conference on cGMP 2022: recent trends in cGMP research and development-meeting report.
Andreas Friebe, Jan R Kraehling, Michael Russwurm, Peter Sandner, Achim Schmidtko

Naunyn Schmiedebergs Arch Pharmacol· August 2023

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The sGC Activator Runcaciguat Has Kidney Protective Effects and Prevents a Decline of Kidney Function in ZSF1 Rats.
Jan R Kraehling, Agnes Benardeau, Tibor Schomber, Laura Popp, Julia Vienenkoetter, Peter Sandner

Int J Mol Sci· August 2023

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Ameliorating diabetes-associated atherosclerosis and diabetic nephropathy through modulation of soluble guanylate cyclase.
Arpeeta Sharma, Judy Choi, Lachlan Sim, Abhiroop Dey, Muthukumar Mohan, Peter Sandner

Front Cardiovasc Med· July 2023

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New Generation of sGC Stimulators: Discovery of Imidazo[1,2-]pyridine Carboxamide BAY 1165747 (BAY-747), a Long-Acting Soluble Guanylate Cyclase Stimulator for the Treatment of Resistant Hypertension.
Alexandros Vakalopoulos, Frank Wunder, Ingo V Hartung, Gorden Redlich, Rolf Jautelat, Peter Sandner

J Med Chem· June 2023

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Treatment effects of soluble guanylate cyclase modulation on diabetic kidney disease at single-cell resolution.
Michael S Balzer, Mira Pavkovic, Julia Frederick, Amin Abedini, Alexius Freyberger, Peter Sandner

Cell Rep Med· April 2023

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CYB5R3 in type II alveolar epithelial cells protects against lung fibrosis by suppressing TGF-β1 signaling.
Marta Bueno, Jazmin Calyeca, Timur Khaliullin, Megan P Miller, Diana Alvarez, Peter Sandner

JCI Insight· March 2023

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Acute deletion of the central MR/GR steroid receptor correlates with changes in LTP, auditory neural gain, and GC-A cGMP signaling.
Dila Calis, Morgan Hess, Philine Marchetta, Wibke Singer, Julian Modro, Peter Sandner

Front Mol Neurosci· February 2023

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Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation.
Carina Mauersberger, Hendrik B Sager, Jana Wobst, Tan An Dang, Laura Lambrecht, Peter Sandner

Nat Cardiovasc Res· December 2022

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Inhaled mosliciguat (BAY 1237592): targeting pulmonary vasculature via activating apo-sGC.
Eva M Becker-Pelster, Michael G Hahn, Martina Delbeck, Lisa Dietz, Jörg Hüser, Peter Sandner

Respir Res· October 2022

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Soluble guanylate cyclase activator BAY 54-6544 improves vasomotor function and survival in an accelerated ageing mouse model.
Ehsan Ataei Ataabadi, Keivan Golshiri, Annika A Jüttner, René de Vries, Ingrid Van den Berg-Garrelds, Peter Sandner

Aging Cell· September 2022

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Treatment with the soluble guanylate cyclase activator BAY 60-2770 normalizes bladder function in an in vivo rat model of chronic prostatitis.
Ozgu Aydogdu, Fernando Perez, Patrik Aronsson, Pinar Uyar Gocun, Thomas Carlsson, Peter Sandner

Eur J Pharmacol· July 2022

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Urinary miRNA Profiles in Chronic Kidney Injury-Benefits of Extracellular Vesicle Enrichment and miRNAs as Potential Biomarkers for Renal Fibrosis, Glomerular Injury, and Endothelial Dysfunction.
Barbara Petzuch, Agnès Bénardeau, Lucas Hofmeister, Jutta Meyer, Elke Hartmann, Peter Sandner

Toxicol Sci· April 2022

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The sGC stimulator BAY-747 and activator runcaciguat can enhance memory in vivo via differential hippocampal plasticity mechanisms.
Ellis Nelissen, Nina Possemis, Nick P Van Goethem, Melissa Schepers, Danielle A J Mulder-Jongen, Peter Sandner

Sci Rep· March 2022

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