Publications by authors named "Ilze Mutule"

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5-membered cyclic hydroxamic acids as HDAC inhibitors.
Ilze Mutule, Diana Borovika, Elina Rozenberga, Nadezhda Romanchikova, Raivis Zalubovskis

J Enzyme Inhib Med Chem· April 2015

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Plasmepsin inhibitory activity and structure-guided optimization of a potent hydroxyethylamine-based antimalarial hit.
Kristaps Jaudzems, Kaspars Tars, Gundars Maurops, Natalija Ivdra, Martins Otikovs, Ilze Mutule

ACS Med Chem Lett· April 2014

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Libiguins A and B: novel phragmalin limonoids isolated from Neobeguea mahafalensis causing profound enhancement of sexual activity.
Solofoniaina Razafimahefa, Felikss Mutulis, Ilze Mutule, Edvards Liepinsh, Maija Dambrova

Planta Med· March 2014

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Oligomerization of indole derivatives with incorporation of thiols.
Felikss Mutulis, Adolf Gogoll, Ilze Mutule, Sviatlana Yahorava, Aleh Yahorau

Molecules· August 2008

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Proteochemometric analysis of small cyclic peptides' interaction with wild-type and chimeric melanocortin receptors.
Aleksejs Kontijevskis, Ramona Petrovska, Ilze Mutule, Staffan Uhlen, Jan Komorowski

Proteins· October 2007

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Design and synthesis of a library of tertiary amides: evaluation as mimetics of the melanocortins' active core.
Felikss Mutulis, Jana Kreicberga, Sviatlana Yahorava, Ilze Mutule, Larisa Borisova-Jan

Bioorg Med Chem· September 2007

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Proteochemometric modeling reveals the interaction site for Trp9 modified alpha-MSH peptides in melanocortin receptors.
Maris Lapinsh, Peteris Prusis, Ramona Petrovska, Staffan Uhlén, Ilze Mutule

Proteins· May 2007

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A look inside HIV resistance through retroviral protease interaction maps.
Aleksejs Kontijevskis, Peteris Prusis, Ramona Petrovska, Sviatlana Yahorava, Felikss Mutulis, Ilze Mutule

PLoS Comput Biol· March 2007

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Kinetic evidence for tandemly arranged ligand binding sites in melanocortin 4 receptor complexes.
Sergei Kopanchuk, Santa Veiksina, Felikss Mutulis, Ilze Mutule, Sviatlana Yahorava

Neurochem Int· October 2006

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Probing the substrate specificity of the dengue virus type 2 NS3 serine protease by using internally quenched fluorescent peptides.
Pornwaratt Niyomrattanakit, Sviatlana Yahorava, Ilze Mutule, Felikss Mutulis, Ramona Petrovska

Biochem J· July 2006

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The MC3 receptor binding affinity of melanocortins correlates with the nitric oxide production inhibition in mice brain inflammation model.
Ruta Muceniece, Liga Zvejniece, Edgars Liepinsh, Olga Kirjanova, Larisa Baumane, Ilze Mutule

Peptides· June 2006

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N-alkylated dipeptide amides and related structures as imitations of the melanocortins' active core.
Felikss Mutulis, Ilze Mutule, Edvards Liepinsh, Aleh Yahorau, Maris Lapinsh

Peptides· October 2005

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Co-operative regulation of ligand binding to melanocortin receptor subtypes: evidence for interacting binding sites.
Sergei Kopanchuk, Santa Veiksina, Ramona Petrovska, Ilze Mutule, Michael Szardenings

Eur J Pharmacol· April 2005

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Proteochemometric mapping of the interaction of organic compounds with melanocortin receptor subtypes.
Maris Lapinsh, Santa Veiksina, Staffan Uhlén, Ramona Petrovska, Ilze Mutule

Mol Pharmacol· January 2005

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New substituted piperazines as ligands for melanocortin receptors. Correlation to the X-ray structure of "THIQ".
Felikss Mutulis, Sviatlana Yahorava, Ilze Mutule, Aleh Yahorau, Edvards Liepinsh

J Med Chem· August 2004

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A simple and effective method for producing nonrandom peptide libraries using cotton as a carrier in continuous flow peptide synthesizers.
Felikss Mutulis, Marcus Tysk, Ilze Mutule, Jarl E S Wikberg

J Comb Chem· June 2003

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QSAR and proteo-chemometric analysis of the interaction of a series of organic compounds with melanocortin receptor subtypes.
Maris Lapinsh, Peteris Prusis, Ilze Mutule, Felikss Mutulis, Jarl E S Wikberg

J Med Chem· June 2003

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Novel selective melanocortin 4 receptor antagonist induces food intake after peripheral administration.
Helgi B Schiöth, Ants Kask, Felikss Mutulis, Ruta Muceniece, Ilga Mutule, Ilze Mutule

Biochem Biophys Res Commun· February 2003

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Subtype selective binding properties of substituted linear melanocyte stimulating hormone analogues.
Helgi B Schiöth, Aster Tesfaye, Felikss Mutulis, Richard Rudzish, Ilze Mutule

Neuropeptides· December 2002

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Design, synthesis and biological evaluation of cyclic angiotensin II analogues with 3,5 side-chain bridges. Role of C-terminal aromatic residue and ring cluster for activity and implications in the drug design of AT1 non-peptide antagonists.
Panagiota Roumelioti, Ludmila Polevaya, Panagiotis Zoumpoulakis, Nektarios Giatas, Ilze Mutule

Bioorg Med Chem Lett· September 2002

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Reductive amination products containing naphthalene and indole moieties bind to melanocortin receptors.
Felikss Mutulis, Ilze Mutule, Maris Lapins, Jarl E S Wikberg

Bioorg Med Chem Lett· April 2002

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N-alkylaminoacids and their derivatives interact with melanocortin receptors.
Felikss Mutulis, Ilze Mutule, Jarl E S Wikberg

Bioorg Med Chem Lett· April 2002

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