Publications by authors named "Staffan Uhlen"

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A new, simple and robust radioligand binding method used to determine kinetic off-rate constants for unlabeled ligands. Application at α2A- and α2C-adrenoceptors.
Staffan Uhlén, Helgi B Schiöth, Jan Anker Jahnsen

Eur J Pharmacol· October 2016

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Perspective on the role of the N-terminal tail of the α2C-adrenoceptor.
Staffan Uhlen, Jan Anker Jahnsen

Naunyn Schmiedebergs Arch Pharmacol· October 2014

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The C-terminal half of the α2C-adrenoceptor determines the receptor's membrane expression level and drug selectivity.
Jan Anker Jahnsen, Staffan Uhlén

Naunyn Schmiedebergs Arch Pharmacol· December 2013

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The N-terminal region of the human 5-HT₂C receptor has as a cleavable signal peptide.
Jan Anker Jahnsen, Staffan Uhlén

Eur J Pharmacol· June 2012

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The predicted N-terminal signal sequence of the human α₂C-adrenoceptor does not act as a functional cleavable signal peptide.
Jan Anker Jahnsen, Staffan Uhlén

Eur J Pharmacol· June 2012

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Proteochemometric analysis of small cyclic peptides' interaction with wild-type and chimeric melanocortin receptors.
Aleksejs Kontijevskis, Ramona Petrovska, Ilze Mutule, Staffan Uhlen, Jan Komorowski

Proteins· October 2007

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Proteochemometric modeling reveals the interaction site for Trp9 modified alpha-MSH peptides in melanocortin receptors.
Maris Lapinsh, Peteris Prusis, Ramona Petrovska, Staffan Uhlén, Ilze Mutule

Proteins· May 2007

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Prediction of indirect interactions in proteins.
Peteris Prusis, Staffan Uhlén, Ramona Petrovska, Maris Lapinsh, Jarl E S Wikberg

BMC Bioinformatics· March 2006

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Improved approach for proteochemometrics modeling: application to organic compound--amine G protein-coupled receptor interactions.
Maris Lapinsh, Peteris Prusis, Staffan Uhlén, Jarl E S Wikberg

Bioinformatics· December 2005

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Nandrolone treatment decreases the alpha1B-adrenoceptor mRNA level in rat kidney, but not the density of alpha1B-adrenoceptors in cultured MDCK-D1 kidney cells.
Jonas Lindblom, Ramona Petrovska, Mathias Hallberg, Kristina Magnusson, Fred Nyberg

Eur J Pharmacol· December 2005

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Addition of a signal peptide sequence to the alpha1D-adrenoceptor gene increases the density of receptors, as determined by [3H]-prazosin binding in the membranes.
Ramona Petrovska, Ivo Kapa, Janis Klovins, Helgi B Schiöth, Staffan Uhlén

Br J Pharmacol· March 2005

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Proteochemometric mapping of the interaction of organic compounds with melanocortin receptor subtypes.
Maris Lapinsh, Santa Veiksina, Staffan Uhlén, Ramona Petrovska, Ilze Mutule

Mol Pharmacol· January 2005

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Investigations on the pharmacology of the cardioprotective guanidine ME10092.
Maija Dambrova, Edgars Liepinsh, Olga Kirjanova, Ramona Petrovska, Osvalds Pugovich, Staffan Uhlen

J Cardiovasc Pharmacol· August 2004

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The methylester of gamma-butyrobetaine, but not gamma-butyrobetaine itself, induces muscarinic receptor-dependent vasodilatation.
Maija Dambrova, Stefan Chlopicki, Edgars Liepinsh, Olga Kirjanova, Olga Gorshkova, Staffan Uhlen

Naunyn Schmiedebergs Arch Pharmacol· May 2004

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Nandrolone treatment decreases the level of rat kidney alpha(1B)-adrenoceptors.
Staffan Uhlén, Jonas Lindblom, Anna Kindlundh, Paul Mugisha, Fred Nyberg

Naunyn Schmiedebergs Arch Pharmacol· August 2003

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Reduced natriuretic response to acute sodium loading in COMT gene deleted mice.
Cecilia Odlind, Ilkka Reenilä, Pekka T Männistö, Risto Juvonen, Staffan Uhlén

BMC Physiol· August 2002

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Binding of [(3)H]prazosin to alpha(1A)- and alpha(1B)-adrenoceptors, and to a cimetidine-sensitive non-alpha(1) binding site in rat kidney membranes.
Paul Mugisha, Dirk Gründemann, Edgar Schömig, Staffan Uhlén

Naunyn Schmiedebergs Arch Pharmacol· May 2002

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