Publications by authors named "Ingileif Jonsdottir"

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Genome-wide association study and polygenic risk prediction of hypothyroidism.
Søren A Rand, Gustav Ahlberg, Vinicius Tragante, Laia M Monfort, Chaoqun Zheng, Ingileif Jonsdottir

Nat Genet· December 2025

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African-ancestry-specific variant IKKβ p.Glu502Lys confers high lupus risk.
Gudny Ella Thorlacius, Erna V Ivarsdottir, Saedis Saevarsdottir, Kristjan H S Moore, Sigurjon A Gudjonsson, Ingileif Jonsdottir

Nat Genet· December 2025

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Observational and Mendelian randomization studies of plasma sclerostin levels do not provide evidence of cardiovascular adverse effects of sclerostin inhibition.
Rosa B Thorolfsdottir, Gardar Sveinbjornsson, Grimur Hjorleifsson Eldjarn, Hildur M Aegisdottir, Unnur Styrkarsdottir, Andrea B Jonsdottir, Ingileif Jonsdottir

Hum Mol Genet· December 2025

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Autoantibody-defined subsets of patients with systemic lupus erythematosus associate with clinical manifestations, NCF2, and HLA DR3-DQ2 genotypes.
Henrik Christian Bidstrup Leffers, Anne Troldborg, Martin Andersen, Ana Cristina Gonzalez Sanchez, Ingileif Jonsdottir

Transl Res· October 2025

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The genetic architecture of fibromyalgia across 2.5 million individuals.
Isabel Kerrebijn, Gyda Bjornsdottir, Keon Arbabi, Lea Urpa, Hele Haapaniemi, Ingileif Jonsdottir

medRxiv· September 2025

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Dose-sparing effects of novel adjuvants and aluminum hydroxide on two different vaccines in a neonatal mouse model.
Jenny Lorena Molina Estupiñan, Poorya Foroutan Pajoohian, Gabriel Kristian Pedersen, Dennis Christensen, Serena Marchi, Ingileif Jonsdottir

Front Immunol· August 2025

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Distinct humoral responses induced by heterologous versus homologous prime-boost immunization strategies in early life.
Poorya Foroutan Pajoohian, Audur Anna Aradottir Pind, Jenny Lorena Molina Estupiñan, Dennis Christensen, Gabriel Kristian Pedersen, Ingileif Jonsdottir

Front Immunol· August 2025

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Genome-wide analyses identify 25 infertility loci and relationships with reproductive traits across the allele frequency spectrum.
Samvida S Venkatesh, Laura B L Wittemans, Duncan S Palmer, Nikolas A Baya, Teresa Ferreira, Ingileif Jonsdottir

Nat Genet· May 2025

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A genome-wide association meta-analysis links hidradenitis suppurativa to common and rare sequence variants causing disruption of the Notch and Wnt/β-catenin signaling pathways.
Rune Kjærsgaard Andersen, Lilja Stefansdottir, Peter Theut Riis, Gisli Halldorsson, Egil Ferkingstad, Ingileif Jonsdottir

J Am Acad Dermatol· April 2025

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Missense variants in FRS3 affect body mass index in populations of diverse ancestries.
Andrea B Jonsdottir, Gardar Sveinbjornsson, Rosa B Thorolfsdottir, Max Tamlander, Vinicius Tragante, Ingileif Jonsdottir

Nat Commun· March 2025

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A partial loss-of-function variant in STAT6 protects against type 2 asthma.
Katla Kristjansdottir, Gudmundur L Norddahl, Erna V Ivarsdottir, Gisli H Halldorsson, Gudmundur Einarsson, Ingileif Jonsdottir

J Allergy Clin Immunol· January 2025

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Genome-Wide Association Study of Accessory Atrioventricular Pathways.
Hildur M Aegisdottir, Laura Andreasen, Rosa B Thorolfsdottir, Gardar Sveinbjornsson, Andrea B Jonsdottir, Ingileif Jonsdottir

JAMA Cardiol· November 2024

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Gene-based burden tests of rare germline variants identify six cancer susceptibility genes.
Erna V Ivarsdottir, Julius Gudmundsson, Vinicius Tragante, Gardar Sveinbjornsson, Snaedis Kristmundsdottir, Ingileif Jonsdottir

Nat Genet· November 2024

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Genome-wide meta-analysis of myasthenia gravis uncovers new loci and provides insights into polygenic prediction.
Alice Braun, Sudhanshu Shekhar, Daniel F Levey, Peter Straub, Julia Kraft

Nat Commun· November 2024

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Homozygosity for a stop-gain variant in CCDC201 causes primary ovarian insufficiency.
Asmundur Oddsson, Valgerdur Steinthorsdottir, Gudjon R Oskarsson, Unnur Styrkarsdottir, Kristjan H S Moore, Ingileif Jonsdottir

Nat Genet· September 2024

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Sequence variants influencing the regulation of serum IgG subclass levels.
Thorunn A Olafsdottir, Gudmar Thorleifsson, Aitzkoa Lopez de Lapuente Portilla, Stefan Jonsson, Lilja Stefansdottir, Ingileif Jonsdottir

Nat Commun· September 2024

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The correlation between CpG methylation and gene expression is driven by sequence variants.
Olafur Andri Stefansson, Brynja Dogg Sigurpalsdottir, Solvi Rognvaldsson, Gisli Hreinn Halldorsson, Kristinn Juliusson, Ingileif Jonsdottir

Nat Genet· August 2024

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Deciphering the genetics and mechanisms of predisposition to multiple myeloma.
Molly Went, Laura Duran-Lozano, Gisli H Halldorsson, Andrea Gunnell, Nerea Ugidos-Damboriena, Ingileif Jonsdottir

Nat Commun· August 2024

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Start codon variant in LAG3 is associated with decreased LAG-3 expression and increased risk of autoimmune thyroid disease.
Saedis Saevarsdottir, Kristbjörg Bjarnadottir, Thorsteinn Markusson, Jonas Berglund, Thorunn A Olafsdottir, Ingileif Jonsdottir

Nat Commun· July 2024

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Author Correction: Large-scale plasma proteomics comparisons through genetics and disease associations.
Grimur Hjorleifsson Eldjarn, Egil Ferkingstad, Sigrun H Lund, Hannes Helgason, Olafur Th Magnusson, Ingileif Jonsdottir

Nature· June 2024

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Variant in the synaptonemal complex protein SYCE2 associates with pregnancy loss through effect on recombination.
Valgerdur Steinthorsdottir, Bjarni V Halldorsson, Hakon Jonsson, Gunnar Palsson, Asmundur Oddsson, Ingileif Jonsdottir

Nat Struct Mol Biol· April 2024

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Genome-wide analyses identify 21 infertility loci and over 400 reproductive hormone loci across the allele frequency spectrum.
Samvida S Venkatesh, Laura B L Wittemans, Duncan S Palmer, Nikolas A Baya, Teresa Ferreira, Ingileif Jonsdottir

medRxiv· March 2024

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Variants at the Interleukin 1 Gene Locus and Pericarditis.
Rosa B Thorolfsdottir, Andrea B Jonsdottir, Gardar Sveinbjornsson, Hildur M Aegisdottir, Asmundur Oddsson, Ingileif Jonsdottir

JAMA Cardiol· February 2024

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[The Nobel Prize in Physiology or Medicine 2023].
Ingileif Jonsdottir

Laeknabladid· December 2023

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Actionable Genotypes and Their Association with Life Span in Iceland.
Brynjar O Jensson, Gudny A Arnadottir, Hildigunnur Katrinardottir, Run Fridriksdottir, Hannes Helgason, Ingileif Jonsdottir

N Engl J Med· November 2023

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