Publications by authors named "Inhou Chu"

Claim this Profile
R
Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical Candidates.
Mihirbaran Mandal, Li Xiao, Weidong Pan, Giovanna Scapin, Guoqing Li, Donald Chu, Inhou Chu

J Med Chem· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The discovery of fused oxadiazepines as gamma secretase modulators for treatment of Alzheimer's disease.
Hongmei Li, Jun Qin, Pawan Dhondi, Wei Zhou, Monica Vicarel, Inhou Chu

Bioorg Med Chem Lett· January 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and SAR Studies of Fused Oxadiazines as γ-Secretase Modulators for Treatment of Alzheimer's Disease.
Xianhai Huang, Wei Zhou, Xiaoxiang Liu, Hongmei Li, George Sun, Inhou Chu

ACS Med Chem Lett· November 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cyclic hydroxyamidines as amide isosteres: discovery of oxadiazolines and oxadiazines as potent and highly efficacious γ-secretase modulators in vivo.
Zhong-Yue Sun, Theodros Asberom, Thomas Bara, Chad Bennett, Duane Burnett, Inhou Chu

J Med Chem· January 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Iminoheterocycles as gamma-secretase modulators.
John P Caldwell, Chad E Bennett, Troy M McCracken, Robert D Mazzola, Thomas Bara, Inhou Chu

Bioorg Med Chem Lett· September 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Discovery of Pyridone and Pyridazone Heterocycles as γ-Secretase Modulators.
Xianhai Huang, Robert Aslanian, Wei Zhou, Xiaohong Zhu, Jun Qin, Inhou Chu

ACS Med Chem Lett· July 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The impact of protein on Caco-2 permeability of low mass balance compounds for absorption projection and efflux substrate identification.
Tongtong Liu, Lee-Jah Chang, Annette Uss, Inhou Chu, Richard A Morrison

J Pharm Biomed Anal· April 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Protein binding-dependent decreases in hERG channel blocker potency assessed by whole-cell voltage clamp in serum.
Michael Margulis, Steve Sorota, Inhou Chu, Anthony Soares, Tony Priestley

J Cardiovasc Pharmacol· April 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Temporal evaluation of CYP mRNA in mice administered with prototypical P450 inducers: comparison with conventional protein/enzyme methods.
Er-Jia Wang, George Mandakas, Jairam Palamanda, Xinjie Lin, Pramila Kumari, Inhou Chu

Drug Chem Toxicol· January 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of amide and heteroaryl isosteres as carbamate replacements in a series of orally active gamma-secretase inhibitors.
Mark D McBriar, John W Clader, Inhou Chu, Robert A Del Vecchio, Leonard Favreau

Bioorg Med Chem Lett· January 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Utility of mass spectrometry for in-vitro ADME assays.
Inhou Chu, Amin A Nomeir

Curr Drug Metab· June 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Blocking ion channel KCNN4 alleviates the symptoms of experimental autoimmune encephalomyelitis in mice.
Eva-Pia Reich, Long Cui, Lily Yang, Catherine Pugliese-Sivo, Andrei Golovko, Inhou Chu, Chuan-Chu Chou

Eur J Immunol· April 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A computer program for automated data evaluation to support in vitro higher-throughput screening for drug metabolism and pharmacokinetics attributes.
Eliza N Fung, Inhou Chu, Amin A Nomeir

Rapid Commun Mass Spectrom· November 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Higher-throughput screening for Caco-2 permeability utilizing a multiple sprayer liquid chromatography/tandem mass spectrometry system.
Eliza N Fung, Inhou Chu, Cheng Li, Tongtong Liu, Anthony Soares

Rapid Commun Mass Spectrom· November 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Assessment of temporal biochemical and gene transcription changes in rat liver cytochrome P450: utility of real-time quantitative RT-PCR.
Federico M Goodsaid, Jairam R Palamanda, Diana Montgomery, George Mandakas, Chunyan Gu, Inhou Chu

Pharm Res· September 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A fully automated nanoelectrospray tandem mass spectrometric method for analysis of Caco-2 samples.
Colleen K Van Pelt, Sheng Zhang, Eliza Fung, Inhou Chu, Tongtong Liu

Rapid Commun Mass Spectrom· August 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The use of in vitro metabolic stability for rapid selection of compounds in early discovery based on their expected hepatic extraction ratios.
Yan Yi Lau, Gopal Krishna, Nathan P Yumibe, Diane E Grotz, Elpida Sapidou, Inhou Chu, Chin-Chung Lin

Pharm Res· November 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Generic fast gradient liquid chromatography/tandem mass spectrometry techniques for the assessment of the in vitro permeability across the blood-brain barrier in drug discovery.
Inhou Chu, Fei Liu, Anthony Soares, Pramila Kumari, Amin A Nomeir

Rapid Commun Mass Spectrom· September 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis