Publications by authors named "Inish O'Doherty"

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Type 1 diabetes prevention clinical trial simulator: Case reports of model-informed drug development tool.
Juan Francisco Morales, Marian Klose, Yannick Hoffert, Jagdeep T Podichetty, Jackson Burton, Inish O'Doherty

CPT Pharmacometrics Syst Pharmacol· August 2024

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Qualifying a Novel Clinical Trial Endpoint (iBOX) Predictive of Long-Term Kidney Transplant Outcomes.
Amanda Klein, Alexandre Loupy, Mark Stegall, Ilkka Helanterä, Luke Kosinski, Inish O'Doherty

Transpl Int· November 2023

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Qualifying a novel clinical trial endpoint (iBOX) predictive of long-term kidney transplant outcomes.
Amanda Klein, Alexandre Loupy, Mark Stegall, Ilkka Helanterä, Luke Kosinski, Inish O'Doherty

Am J Transplant· October 2023

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Longitudinal estimated glomerular filtration rate (eGFR) modeling in long-term renal function to inform clinical trial design in kidney transplantation.
Luke Kosinski, Eric Frey, Amanda Klein, Inish O'Doherty, Klaus Romero

Clin Transl Sci· September 2023

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Disease progression joint model predicts time to type 1 diabetes onset: Optimizing future type 1 diabetes prevention studies.
Juan Francisco Morales, Rhoda Muse, Jagdeep T Podichetty, Jackson Burton, Sarah David, Inish O'Doherty

CPT Pharmacometrics Syst Pharmacol· July 2023

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Consortium-based approach to receiving an EMA qualification opinion on the use of islet autoantibodies as enrichment biomarkers in type 1 diabetes clinical studies.
Stephen R Karpen, Jessica L Dunne, Brigitte I Frohnert, Marjana Marinac, Claudia Richard, Inish M O'Doherty

Diabetologia· March 2023

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Leveraging Real-World Data for EMA Qualification of a Model-Based Biomarker Tool to Optimize Type-1 Diabetes Prevention Studies.
Jagdeep T Podichetty, Patrick Lang, Inish M O'Doherty, Sarah E David, Rhoda N Muse

Clin Pharmacol Ther· May 2022

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Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer.
Kevin D Freeman-Cook, Robert L Hoffman, Douglas C Behenna, Britton Boras, Jordan Carelli, Inish O'Doherty

J Med Chem· July 2021

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Effective Data Sharing as a Conduit for Advancing Medical Product Development.
Stephen R Karpen, J Kael White, Ariana P Mullin, Inish O'Doherty, Lynn D Hudson

Ther Innov Regul Sci· May 2021

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The Role of Patient-reported Outcomes and Medication Adherence Assessment in Patient-focused Drug Development for Solid Organ Transplantation.
Stephen R Karpen, Amanda Klein, Rita R Alloway, Renata Albrecht, Ozlem Belen, Inish O'Doherty

Transplantation· May 2021

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Use of biomarkers to improve immunosuppressive drug development and outcomes in renal organ transplantation: A meeting report.
Roslyn B Mannon, Randall E Morris, Michael Abecassis, David Axelrod, Shukal Bala, Inish O'Doherty

Am J Transplant· June 2020

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Recommended Treatment for Antibody-mediated Rejection After Kidney Transplantation: The 2019 Expert Consensus From the Transplantion Society Working Group.
Carrie A Schinstock, Roslyn B Mannon, Klemens Budde, Anita S Chong, Mark Haas, Inish O'Doherty

Transplantation· May 2020

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The importance of drug safety and tolerability in the development of new immunosuppressive therapy for transplant recipients: The Transplant Therapeutics Consortium's position statement.
Mark D Stegall, Kenneth Troy Somerville, Matthew J Everly, Roslyn B Mannon, A Osama Gaber, Inish O'Doherty

Am J Transplant· March 2019

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Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis.
Olugbeminiyi Fadeyi, Mihir D Parikh, Ming Z Chen, Robert E Kyne, Alexandria P Taylor, Inish O'Doherty

Chembiochem· October 2016

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Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism.
Kay Ahn, Markus Boehm, Matthew F Brown, Jessica Calloway, Ye Che, Inish O'Doherty

ACS Chem Biol· September 2016

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Tomato receptor FLAGELLIN-SENSING 3 binds flgII-28 and activates the plant immune system.
Sarah R Hind, Susan R Strickler, Patrick C Boyle, Diane M Dunham, Zhilong Bao, Inish M O'Doherty

Nat Plants· August 2016

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Identification of multiple salicylic acid-binding proteins using two high throughput screens.
Murli Manohar, Miaoying Tian, Magali Moreau, Sang-Wook Park, Hyong Woo Choi, Inish O'Doherty

Front Plant Sci· January 2015

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Interaction of structure-specific and promiscuous G-protein-coupled receptors mediates small-molecule signaling in Caenorhabditis elegans.
Donha Park, Inish O'Doherty, Rishi K Somvanshi, Axel Bethke, Frank C Schroeder

Proc Natl Acad Sci U S A· June 2012

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Synthesis of caeliferins, elicitors of plant immune responses: accessing lipophilic natural products via cross metathesis.
Inish O'Doherty, Joshua J Yim, Eric A Schmelz, Frank C Schroeder

Org Lett· November 2011

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