Publications by authors named "Irati Macaya"

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RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis.
Higinio Dopeso, Paulo Rodrigues, Fernando Cartón-García, Irati Macaya, Josipa Bilic

iScience· April 2024

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Trametinib sensitizes KRAS-mutant lung adenocarcinoma tumors to PD-1/PD-L1 axis blockade via Id1 downregulation.
Ander Puyalto, María Rodríguez-Remírez, Inés López, Irati Macaya, Elizabeth Guruceaga

Mol Cancer· April 2024

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Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer.
Irati Macaya, Marta Roman, Connor Welch, Rodrigo Entrialgo-Cadierno, Marina Salmon

Nat Commun· October 2023

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Correction: The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer.
Rodrigo Entrialgo-Cadierno, Cristina Cueto-Ureña, Connor Welch, Iker Feliu, Irati Macaya

Mol Cancer· June 2023

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The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer.
Rodrigo Entrialgo-Cadierno, Cristina Cueto-Ureña, Connor Welch, Iker Feliu, Irati Macaya

Mol Cancer· May 2023

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LAMC2 Regulates Key Transcriptional and Targetable Effectors to Support Pancreatic Cancer Growth.
Oihane Erice, Shruthi Narayanan, Iker Feliu, Rodrigo Entrialgo-Cadierno, Antonia Malinova, Irati Macaya

Clin Cancer Res· March 2023

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Myosin Vb as a tumor suppressor gene in intestinal cancer.
Fernando Cartón-García, Bruno Brotons, Estefanía Anguita, Higinio Dopeso, Jordi Tarragona, Irati Macaya

Oncogene· December 2022

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Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis.
Sergio Ortiz-Espinosa, Xabier Morales, Yaiza Senent, Diego Alignani, Beatriz Tavira, Irati Macaya

Cancer Lett· March 2022

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FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted.
Adrián Vallejo, Oihane Erice, Rodrigo Entrialgo-Cadierno, Iker Feliu, Elizabeth Guruceaga, Irati Macaya

J Hepatol· August 2021

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Liver Kinase B1 (LKB1) Loss Has its p-ERKs: ERK Inactivation as a Vulnerability in NSCLC With LKB1 Mutations.
Irati Macaya, Rodrigo Entrialgo-Cadierno, Karmele Valencia, Silvestre Vicent

J Thorac Oncol· March 2020

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Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade.
Daniel Ajona, Sergio Ortiz-Espinosa, Teresa Lozano, Francisco Exposito, Alfonso Calvo, Irati Macaya

Nat Cancer· January 2020

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Silencing of adaptor protein SH3BP2 reduces KIT/PDGFRA receptors expression and impairs gastrointestinal stromal tumors growth.
Eva Serrano-Candelas, Erola Ainsua-Enrich, Arnau Navinés-Ferrer, Paulo Rodrigues, Alfonso García-Valverde, Irati Macaya

Mol Oncol· August 2018

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Mechanisms of inactivation of the tumour suppressor gene RHOA in colorectal cancer.
Higinio Dopeso, Paulo Rodrigues, Josipa Bilic, Sarah Bazzocco, Fernando Cartón-García, Irati Macaya

Br J Cancer· January 2018

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Loss of the EPH receptor B6 contributes to colorectal cancer metastasis.
Silvia Mateo-Lozano, Sarah Bazzocco, Paulo Rodrigues, Rocco Mazzolini, Elena Andretta, Irati Macaya

Sci Rep· March 2017

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Investigation of the role of tyrosine kinase receptor EPHA3 in colorectal cancer.
Elena Andretta, Fernando Cartón-García, Águeda Martínez-Barriocanal, Priscila Guimarães de Marcondes, Lizbeth M Jimenez-Flores, Irati Macaya

Sci Rep· February 2017

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Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment.
Sarah Bazzocco, Higinio Dopeso, Fernando Carton-Garcia, Irati Macaya, Elena Andretta

Clin Cancer Res· August 2015

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Myo5b knockout mice as a model of microvillus inclusion disease.
Fernando Cartón-García, Arend W Overeem, Rocio Nieto, Sarah Bazzocco, Higinio Dopeso, Irati Macaya

Sci Rep· July 2015

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RHOA inactivation enhances Wnt signalling and promotes colorectal cancer.
Paulo Rodrigues, Irati Macaya, Sarah Bazzocco, Rocco Mazzolini, Elena Andretta

Nat Commun· November 2014

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Brush border myosin Ia inactivation in gastric but not endometrial tumors.
Rocco Mazzolini, Paulo Rodrigues, Sarah Bazzocco, Higinio Dopeso, Ana M Ferreira, Irati Macaya

Int J Cancer· April 2013

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