Publications by authors named "Ireos Filipuzzi"

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Multiple Genes Core to ERAD, Macroautophagy and Lysosomal Degradation Pathways Participate in the Proteostasis Response in α1-Antitrypsin Deficiency.
Jie Li, Francesca Moretti, Tunda Hidvegi, Sanja Sviben, James A J Fitzpatrick, Ireos Filipuzzi

Cell Mol Gastroenterol Hepatol· May 2024

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Kendomycin Cytotoxicity against Bacterial, Fungal, and Mammalian Cells Is Due to Cation Chelation.
Dale Tranter, Ireos Filipuzzi, Thomas Lochmann, Britta Knapp, Juho Kellosalo

J Nat Prod· April 2020

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Target of rapamycin complex 2-dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in .
Clélia Bourgoint, Delphine Rispal, Marina Berti, Ireos Filipuzzi, Stephen B Helliwell

J Biol Chem· August 2018

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Target Identification and Mechanism of Action of Picolinamide and Benzamide Chemotypes with Antifungal Properties.
Verena Pries, Christina Nöcker, Danish Khan, Philipp Johnen, Zebin Hong, Ireos Filipuzzi

Cell Chem Biol· March 2018

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Stendomycin selectively inhibits TIM23-dependent mitochondrial protein import.
Ireos Filipuzzi, Janos Steffen, Mitchel Germain, Laetitia Goepfert, Michael A Conti

Nat Chem Biol· December 2017

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Direct Interaction of Chivosazole F with Actin Elicits Cell Responses Similar to Latrunculin A but Distinct from Chondramide.
Ireos Filipuzzi, Jason Ray Thomas, Verena Pries, David Estoppey, Michael Salcius

ACS Chem Biol· September 2017

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The Natural Product Cavinafungin Selectively Interferes with Zika and Dengue Virus Replication by Inhibition of the Host Signal Peptidase.
David Estoppey, Chia Min Lee, Marco Janoschke, Boon Heng Lee, Kah Fei Wan, Ireos Filipuzzi

Cell Rep· April 2017

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High-Resolution Genetics Identifies the Lipid Transfer Protein Sec14p as Target for Antifungal Ergolines.
Ireos Filipuzzi, Simona Cotesta, Francesca Perruccio, Britta Knapp, Yue Fu

PLoS Genet· November 2016

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Advantages and Challenges of Phenotypic Screens: The Identification of Two Novel Antifungal Geranylgeranyltransferase I Inhibitors.
Verena Pries, Simona Cotesta, Ralph Riedl, Thomas Aust, Sven Schuierer, Ireos Filipuzzi

J Biomol Screen· March 2016

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FR171456 is a specific inhibitor of mammalian NSDHL and yeast Erg26p.
Stephen B Helliwell, Shantanu Karkare, Marc Bergdoll, Alain Rahier, Juliet R Leighton-Davis, Ireos Filipuzzi

Nat Commun· October 2015

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Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways.
Delphine Rispal, Sandra Eltschinger, Michael Stahl, Stefania Vaga, Bernd Bodenmiller, Ireos Filipuzzi

J Biol Chem· June 2015

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High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions.
Dominic Hoepfner, Stephen B Helliwell, Heather Sadlish, Sven Schuierer, Ireos Filipuzzi

Microbiol Res· September 2014

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TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks.
Kenji Shimada, Ireos Filipuzzi, Michael Stahl, Stephen B Helliwell, Christian Studer

Mol Cell· September 2013

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Synthesis and characterization of fluorescent ubiquitin derivatives as highly sensitive substrates for the deubiquitinating enzymes UCH-L3 and USP-2.
Aline Tirat, Alain Schilb, Virginie Riou, Lukas Leder, Bernd Gerhartz, Ireos Filipuzzi

Anal Biochem· August 2005

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Evidence for ligand-independent transcriptional activation of the human estrogen-related receptor alpha (ERRalpha): crystal structure of ERRalpha ligand binding domain in complex with peroxisome proliferator-activated receptor coactivator-1alpha.
Joerg Kallen, Jean-Marc Schlaeppi, Francis Bitsch, Ireos Filipuzzi, Alain Schilb

J Biol Chem· November 2004

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Development and implementation of a highly miniaturized confocal 2D-FIDA-based high-throughput screening assay to search for active site modulators of the human heat shock protein 90beta.
Alain Schilb, Virginie Riou, Joseph Schoepfer, Johannes Ottl, Kurt Müller, Ireos Filipuzzi

J Biomol Screen· October 2004

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SpeedScreen: The "missing link" between genomics and lead discovery.
Hartmut Zehender, Francois Le Goff, Natalie Lehmann, Ireos Filipuzzi, Lorenz M Mayr

J Biomol Screen· September 2004

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