Publications by authors named "Irtisha Singh"

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Nanomaterial-induced mitochondrial biogenesis enhances intercellular mitochondrial transfer efficiency.
John Soukar, Kanwar Abhay Singh, Ari Aviles, Sarah Hargett, Harman Kaur, Irtisha Singh

Proc Natl Acad Sci U S A· October 2025

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Understanding proneural-mesenchymal transition using patient-derived glioma stem-like cell (GSC) organoids and engineered extracellular matrix.
Autumn McManis, Charles Ashley Jimenez, Abha Shirolkar, Syed Raza Ur Rehman, Sumana Mallick, Irtisha Singh

bioRxiv· September 2025

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Nanosilicates promote angiogenesis through activation of ROS-mediated WNT/β-catenin pathway.
Giriraj Lokhande, Kanwar Abhay Singh, Shounak Roy, John Soukar, Anna Kersey, Irtisha Singh

Sci Adv· July 2025

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Correction: Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma.
Stephen C Mack, Irtisha Singh, Xiuxing Wang, Rachel Hirsch, Quilian Wu

J Exp Med· June 2025

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Engineering a Microfluidic Platform to Cryopreserve Stem Cells: A DMSO-Free Sustainable Approach.
Saman Modaresi, Settimio Pacelli, Aishik Chakraborty, Ali Coyle, Wei Luo, Irtisha Singh

Adv Healthc Mater· November 2024

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Intrinsic Epigenetic State of Primary Osteosarcoma Drives Metastasis.
Irtisha Singh, Nino Rainusso, Lyazat Kurenbekova, Bikesh K Nirala, Juan Dou

Mol Cancer Res· September 2024

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Atomic vacancies of molybdenum disulfide nanoparticles stimulate mitochondrial biogenesis.
Kanwar Abhay Singh, John Soukar, Mohammad Zulkifli, Anna Kersey, Giriraj Lokhande, Irtisha Singh

Nat Commun· September 2024

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Genetic variation drives cancer cell adaptation to ECM stiffness.
Ting-Ching Wang, Suchitaa Sawhney, Daylin Morgan, Richard L Bennett, Richa Rashmi, Irtisha Singh

Proc Natl Acad Sci U S A· September 2024

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Inorganic Biomaterials Shape the Transcriptome Profile to Induce Endochondral Differentiation.
Aparna Murali, Anna M Brokesh, Lauren M Cross, Anna L Kersey, Manish K Jaiswal, Irtisha Singh

Adv Sci (Weinh)· August 2024

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Inorganic ions activate lineage-specific gene regulatory networks.
Anna L Kersey, Irtisha Singh, Akhilesh K Gaharwar

Acta Biomater· July 2024

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Stiffness assisted cell-matrix remodeling trigger 3D mechanotransduction regulatory programs.
Anna L Kersey, Daniel Y Cheng, Kaivalya A Deo, Christina R Dubell, Ting-Ching Wang, Irtisha Singh

Biomaterials· April 2024

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Intrinsic epigenetic state of primary osteosarcoma drives metastasis.
Irtisha Singh, Nino Rainusso, Lyazat Kurenbekova, Bikesh K Nirala, Juan Dou

bioRxiv· November 2023

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A synthetic tumour microenvironment.
Akhilesh K Gaharwar, Irtisha Singh

Nat Mater· April 2023

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Inhibition of ERK 1/2 pathway downregulates YAP1/TAZ signaling in human cardiomyocytes exposed to hyperglycemic conditions.
Binata Joddar, Carla D Loyola, Salma P Ramirez, Irtisha Singh

Biochem Biophys Res Commun· March 2023

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Dissociation of nanosilicates induces downstream endochondral differentiation gene expression program.
Anna M Brokesh, Lauren M Cross, Anna L Kersey, Aparna Murali, Christopher Richter, Irtisha Singh

Sci Adv· April 2022

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ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma.
Amir Arabzade, Yanhua Zhao, Srinidhi Varadharajan, Hsiao-Chi Chen, Selin Jessa, Irtisha Singh

Cancer Discov· September 2021

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Photothermal modulation of human stem cells using light-responsive 2D nanomaterials.
James K Carrow, Kanwar Abhay Singh, Manish K Jaiswal, Adelina Ramirez, Giriraj Lokhande, Irtisha Singh

Proc Natl Acad Sci U S A· June 2020

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Nanoengineered Osteoinductive Bioink for 3D Bioprinting Bone Tissue.
David Chimene, Logan Miller, Lauren M Cross, Manish K Jaiswal, Irtisha Singh

ACS Appl Mater Interfaces· April 2020

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A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor.
Patrick Sin-Chan, Iqra Mumal, Tannu Suwal, Ben Ho, Xiaolian Fan, Irtisha Singh, Sheila K Singh

Cancer Cell· July 2019

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Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma.
Stephen C Mack, Irtisha Singh, Xiuxing Wang, Rachel Hirsch, Quilian Wu

J Exp Med· May 2019

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Non-overlapping Control of Transcriptome by Promoter- and Super-Enhancer-Associated Dependencies in Multiple Myeloma.
Mariateresa Fulciniti, Charles Y Lin, Mehmet K Samur, Michael A Lopez, Irtisha Singh

Cell Rep· December 2018

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Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia.
Shih-Han Lee, Irtisha Singh, Sarah Tisdale, Omar Abdel-Wahab, Christina S Leslie

Nature· September 2018

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Widespread changes in transcriptome profile of human mesenchymal stem cells induced by two-dimensional nanosilicates.
James K Carrow, Lauren M Cross, Robert W Reese, Manish K Jaiswal, Carl A Gregory, Irtisha Singh

Proc Natl Acad Sci U S A· April 2018

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Widespread intronic polyadenylation diversifies immune cell transcriptomes.
Irtisha Singh, Shih-Han Lee, Adam S Sperling, Mehmet K Samur, Yu-Tzu Tai

Nat Commun· April 2018

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Affinity regression predicts the recognition code of nucleic acid-binding proteins.
Raphael Pelossof, Irtisha Singh, Julie L Yang, Matthew T Weirauch, Timothy R Hughes

Nat Biotechnol· December 2015

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