Publications by authors named "Isaac John"

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Intrathalamic delivery of adeno-associated viral vector expressing progranulin as gene therapy for GRN-related frontotemporal dementia.
Youn Bok Lee, Do Young Lee, Zoe Walker, Joseph Allison, Aleksandra Kaliszewska, John Isaac

Mol Ther Methods Clin Dev· December 2025

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Evaluating Sarcopenia Prevalence in Cirrhotic Patients and Its Association With Child-Turcotte-Pugh and MELD (Model for End-Stage Liver Disease) Scores: A Cross-Sectional Study.
Isaac I John, Modi Jainish Kamlesh Kumar, Farisha Koppath Parammal, Sheryl Elsa Abraham, Sheetal Adem

Cureus· November 2025

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The Ethnic/Racial Variations of Intracerebral Hemorrhage Genetics (ERICH-GENE) Study Protocol.
Guido J Falcone, Stacey Q Wolfe, Marialuisa Zedde, Rosario Pascarella, Jordi Jimenez-Conde, Isaac John

medRxiv· June 2025

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Germline-targeting HIV Envelope SOSIP immunization more frequently elicits broadly-neutralizing antibody precursor responses in infant compared to juvenile rhesus macaques.
Yasmine A Issah, Xintao Hu, John Isaac, Xiaoying Shen, Dominique Davis, John M Ramos, John P Moore

bioRxiv· May 2025

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Liver transplantation for critically ill patients with acute on chronic liver failure: a prospective national programme of waitlist prioritisation.
William Bernal, Rhiannon Taylor, Ian A Rowe, Abhishek Chauhan, Matthew J Armstrong, John Isaac

Lancet Reg Health Eur· November 2024

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Astodrimer Sodium Nasal Spray versus Placebo in Non-Hospitalised Patients with COVID-19: A Randomised, Double-Blinded, Placebo-Controlled Trial.
Stephen Winchester, Alex Castellarnau, Kashif Jabbar, Meera Nadir, Kapila Ranasinghe, Isaac John

Pharmaceutics· September 2024

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Hepatic vein reconstruction during hepatectomy: A feasible and underused technique.
Manish Ahuja, Kunal Joshi, Chris Coldham, Paulo Muiesan, Bobby Dasari, John Isaac

Hepatobiliary Pancreat Dis Int· August 2024

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Immunization with germ line-targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques.
Ashley N Nelson, Xiaoying Shen, Sravani Vekatayogi, Shiyu Zhang, Gabriel Ozorowski, John Isaac, John P Moore

Sci Immunol· August 2024

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Discarded livers tested by normothermic machine perfusion in the VITTAL trial: Secondary end points and 5-year outcomes.
Hynek Mergental, Richard W Laing, Amanda J Kirkham, George Clarke, Yuri L Boteon, John R Isaac

Liver Transpl· January 2024

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Personalised care packages for people with rheumatoid arthritis: a mixed-methods study.
Mrinalini Dey, Amanda Busby, John Isaac, Arthur Pratt, Mwidimi Ndosi

RMD Open· January 2024

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Germline-targeting SOSIP trimer immunization elicits precursor CD4 binding-site targeting broadly neutralizing antibodies in infant macaques.
Ashley N Nelson, Xiaoying Shen, Sravani Vekatayogi, Shiyu Zhang, Gabriel Ozorowski, John Isaac, John P Moore

bioRxiv· November 2023

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Vein Wall Invasion Is a More Reliable Predictor of Oncological Outcomes than Vein-Related Margins after Pancreaticoduodenectomy for Early Stages of Pancreatic Ductal Adenocarcinoma.
Manish Ahuja, Rupaly Pandé, Shafiq Chugtai, Rachel M Brown, Owen Cain, John Isaac

Diagnostics (Basel)· November 2023

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Emergency retransplant for primary non-function of liver allograft.
James M Halle-Smith, Lewis A Hall, Angus Hann, John L Isaac, Nick Murphy

Br J Surg· September 2023

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Liver transplantation for isolated unresectable colorectal liver metastases - Protocol for a service evaluation in the United Kingdom - UKCoMET study.
Krishna Menon, Aarathi Vijayashanker, Jamie Murphy, Pål-Dag Line, John Isaac

HPB (Oxford)· June 2023

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Low C-reactive Protein and Urea Distinguish Primary Nonfunction From Early Allograft Dysfunction Within 48 Hours of Liver Transplantation.
James M Halle-Smith, Lewis Hall, Angus Hann, Asif Arshad, Matthew J Armstrong, John L Isaac

Transplant Direct· June 2023

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Potential clinical utility of intraoperative fluid amylase measurement during pancreaticoduodenectomy.
Kunal Joshi, Manuel Abradelo, David Christopher Bartlett, Nikolaos Chatzizacharias, Bobby Venkata Dasari, John Isaac

Ann Hepatobiliary Pancreat Surg· May 2023

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Leflunomide treatment for patients hospitalised with COVID-19: DEFEAT-COVID randomised controlled trial.
Ines Kralj-Hans, Kuo Li, Adrian Wesek, Alexia Lamorgese, Fatima Omar, Isaac John

BMJ Open· April 2023

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Points to consider for cost-effective use of biological and targeted synthetic DMARDs in inflammatory rheumatic diseases: results from an umbrella review and international Delphi study.
Céleste J T van der Togt, Bart Van den Bemt, Daniel Aletaha, Rieke Alten, Katerina Chatzidionysiou, John Isaac

RMD Open· March 2023

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Where Are We Now with Liver Transplantation in Neuroendocrine Neoplasms? The Place of Liver Transplantation for Grades 1 and 2 Well-Differentiated Unresectable Liver Metastatic Neuroendocrine Tumours.
Tahir Shah, Derek M Manas, Samuel J Ford, Bobby V M Dasari, Paul Gibbs, John Isaac

Curr Oncol Rep· February 2023

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Early postoperative risk stratification in patients with pancreatic fistula after pancreaticoduodenectomy.
Syed S Raza, Anisa Nutu, Sarah Powell-Brett, Alessio Marchetti, Giampaolo Perri, John Isaac

Surgery· February 2023

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Tricuspid Regurgitation in Acute Heart Failure: Predicting Outcome Using Novel Quantitative Echocardiography Techniques.
Max Berrill, Eshan Ashcroft, David Fluck, Isaac John, Ian Beeton

Diagnostics (Basel)· December 2022

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Incidence of Gastrointestinal Bleeding After Transesophageal Echocardiography Use in Orthotopic Liver Transplantation.
Minesh Chotalia, Upasana Topiwala, Asim Iqbal, Dhruv Parekh, John L Isaac

Transpl Int· November 2022

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Management of Ascites Following Deceased Donor Liver Transplantation: A Case Series.
Mohammad Al-Zoubi, Moath Alarabiyat, Angus Hann, Homoyon Mehrzhad, Salil Karkhanis, John R Isaac

Transplant Direct· August 2022

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Safety of Intraoperative Blood Salvage During Liver Transplantation in Patients With Hepatocellular Carcinoma: A Systematic Review and Meta-analysis.
Virginia J Aijtink, Vera C Rutten, Beatrice E M Meijer, Renate de Jong, John L Isaac

Ann Surg· August 2022

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Therapeutic drug monitoring of biopharmaceuticals in inflammatory rheumatic and musculoskeletal disease: a systematic literature review informing EULAR points to consider.
Charlotte Krieckaert, Borja Hernández-Breijo, Johanna Elin Gehin, Guillaume le Mélédo, Alejandro Balsa, John Isaac

RMD Open· June 2022

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