Publications by authors named "Isaac Zentner"

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Author Correction: Chimeric antigen receptor macrophages (CAR-M) sensitize HER2+ solid tumors to PD1 blockade in pre-clinical models.
Stefano Pierini, Rashid Gabbasov, Maria Cecilia Oliveira-Nunes, Rehman Qureshi, Alison Worth, Isaac Zentner

Nat Commun· March 2025

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Chimeric antigen receptor macrophages (CAR-M) sensitize HER2+ solid tumors to PD1 blockade in pre-clinical models.
Stefano Pierini, Rashid Gabbasov, Maria Cecilia Oliveira-Nunes, Rehman Qureshi, Alison Worth, Isaac Zentner

Nat Commun· January 2025

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Determination of Rifampin Concentrations by Urine Colorimetry and Mobile Phone Readout for Personalized Dosing in Tuberculosis Treatment.
Claire Szipszky, Daniel Van Aartsen, Sarah Criddle, Prakruti Rao, Isaac Zentner

J Pediatric Infect Dis Soc· March 2021

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Redox Imbalance and Oxidative DNA Damage During Isoniazid Treatment of HIV-Associated Tuberculosis: A Clinical and Translational Pharmacokinetic Study.
Isaac Zentner, Hyun-Moon Back, Leonid Kagan, Selvakumar Subbian, Jyothi Nagajyothi

Front Pharmacol· July 2020

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Attainment of target rifampicin concentrations in cerebrospinal fluid during treatment of tuberculous meningitis.
Alyssa Mezochow, Kiran T Thakur, Isaac Zentner, Selvakumar Subbian, Leonid Kagan

Int J Infect Dis· July 2019

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Urine colorimetry for therapeutic drug monitoring of pyrazinamide during tuberculosis treatment.
Isaac Zentner, Chawangwa Modongo, Nicola M Zetola, Jotam G Pasipanodya, Shashikant Srivastava

Int J Infect Dis· March 2018

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A Pilot Study of Immune Activation and Rifampin Absorption in HIV-Infected Patients without Tuberculosis Infection: A Short Report.
Christopher Vinnard, Isabel Manley, Brittney Scott, Mariana Bernui, Joella Adams, Isaac Zentner

Tuberc Res Treat· December 2017

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IgG Binding Characteristics of Rhesus Macaque FcγR.
Ying N Chan, Austin W Boesch, Nana Y Osei-Owusu, Ali Emileh, Andrew R Crowley, Isaac Zentner

J Immunol· October 2016

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Urine colorimetry to detect Low rifampin exposure during tuberculosis therapy: a proof-of-concept study.
Isaac Zentner, Hans P Schlecht, Lorna Khensouvann, Neo Tamuhla, Michele Kutzler

BMC Infect Dis· June 2016

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Abasic phosphorothioate oligomers inhibit HIV-1 reverse transcription and block virus transmission across polarized ectocervical organ cultures.
Joseph A Fraietta, Yvonne M Mueller, Karissa L Lozenski, Deena Ratner, Alina C Boesteanu, Isaac J Zentner

Antimicrob Agents Chemother· December 2014

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An optimized, synthetic DNA vaccine encoding the toxin A and toxin B receptor binding domains of Clostridium difficile induces protective antibody responses in vivo.
Scott M Baliban, Amanda Michael, Berje Shammassian, Shikata Mudakha, Amir S Khan, Isaac Zentner

Infect Immun· October 2014

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Structure of the complex between teicoplanin and a bacterial cell-wall peptide: use of a carrier-protein approach.
Nicoleta J Economou, Isaac J Zentner, Edwin Lazo, Jean Jakoncic, Vivian Stojanoff

Acta Crystallogr D Biol Crystallogr· April 2013

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Identification of a small-molecule inhibitor of HIV-1 assembly that targets the phosphatidylinositol (4,5)-bisphosphate binding site of the HIV-1 matrix protein.
Isaac Zentner, Luz-Jeannette Sierra, Ayesha K Fraser, Lina Maciunas, Marie K Mankowski

ChemMedChem· March 2013

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HIV-1 Env gp120 structural determinants for peptide triazole dual receptor site antagonism.
Ferit Tuzer, Navid Madani, Kantharaju Kamanna, Isaac Zentner, Judith LaLonde

Proteins· February 2013

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Discovery of a small-molecule antiviral targeting the HIV-1 matrix protein.
Isaac Zentner, Luz-Jeannette Sierra, Lina Maciunas, Andrei Vinnik, Peter Fedichev

Bioorg Med Chem Lett· February 2013

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Inhibiting early-stage events in HIV-1 replication by small-molecule targeting of the HIV-1 capsid.
Sandhya Kortagere, Navid Madani, Marie K Mankowski, Arne Schön, Isaac Zentner

J Virol· August 2012

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Inhibition of homologous recombination in human cells by targeting RAD51 recombinase.
Fei Huang, Olga M Mazina, Isaac J Zentner, Simon Cocklin, Alexander V Mazin

J Med Chem· April 2012

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A carrier protein strategy yields the structure of dalbavancin.
Nicoleta J Economou, Virginie Nahoum, Stephen D Weeks, Kimberly C Grasty, Isaac J Zentner

J Am Chem Soc· March 2012

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Conformational and structural features of HIV-1 gp120 underlying the dual receptor antagonism by cross-reactive neutralizing antibody m18.
Syna Kuriakose Gift, Isaac J Zentner, Arne Schön, Karyn McFadden, M Umashankara

Biochemistry· April 2011

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Monoclonal antibody m18 paratope leading to dual receptor antagonism of HIV-1 gp120.
Syna Kuriakose Gift, Karyn McFadden, Isaac J Zentner, Srivats Rajagopal, Mei-Yun Zhang

Biochemistry· April 2011

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The active core in a triazole peptide dual-site antagonist of HIV-1 gp120.
Muddegowda Umashankara, Karyn McFadden, Isaac Zentner, Arne Schön, Srivats Rajagopal

ChemMedChem· November 2010

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Introducing metallocene into a triazole peptide conjugate reduces its off-rate and enhances its affinity and antiviral potency for HIV-1 gp120.
Hosahudya Gopi, Simon Cocklin, Vanessa Pirrone, Karyn McFadden, Ferit Tuzer, Isaac Zentner

J Mol Recognit· April 2009

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Structural determinants for affinity enhancement of a dual antagonist peptide entry inhibitor of human immunodeficiency virus type-1.
Hosahudya Gopi, M Umashankara, Vanessa Pirrone, Judith LaLonde, Navid Madani, Isaac Zentner

J Med Chem· May 2008

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Wistar Kyoto and Wistar rats differ in the affective and locomotor effects of nicotine.
Anthony S Rauhut, Isaac J Zentner, Stacey K Mardekian, Jason B Tanenbaum

Physiol Behav· January 2008

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