Publications by authors named "Isabel Faust"

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Development of a xylosyltransferase-I-selective UPLC MS/MS activity assay using a specific acceptor peptide.
Bastian Fischer, Joachim Kuhn, Thanh-Diep Ly, Vanessa Schmidt, Anika Kleine, Isabel Faust

Biochimie· May 2021

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Cytokine-mediated induction of human xylosyltransferase-I in systemic sclerosis skin fibroblasts.
Thanh-Diep Ly, Anika Kleine, Ricarda Plümers, Bastian Fischer, Vanessa Schmidt, Isabel Faust

Biochem Biophys Res Commun· April 2021

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Statins as a Therapeutic Approach for the Treatment of Pseudoxanthoma Elasticum Patients: Evaluation of the Spectrum Efficacy of Atorvastatin In Vitro.
Janina Tiemann, Christopher Lindenkamp, Ricarda Plümers, Isabel Faust, Cornelius Knabbe

Cells· February 2021

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Genetic deletion of Abcc6 disturbs cholesterol homeostasis in mice.
Bettina Ibold, Janina Tiemann, Isabel Faust, Uta Ceglarek, Julia Dittrich

Sci Rep· January 2021

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Linking ABCC6 Deficiency in Primary Human Dermal Fibroblasts of PXE Patients to p21-Mediated Premature Cellular Senescence and the Development of a Proinflammatory Secretory Phenotype.
Janina Tiemann, Thomas Wagner, Christopher Lindenkamp, Ricarda Plümers, Isabel Faust

Int J Mol Sci· December 2020

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Identification of Putative Non-Substrate-Based XT-I Inhibitors by Natural Product Library Screening.
Thanh-Diep Ly, Anika Kleine, Bastian Fischer, Vanessa Schmidt, Doris Hendig, Isabel Faust

Biomolecules· October 2020

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Retinal findings in carriers of monoallelic mutations.
Martin Gliem, Isabel Wieg, Johannes Birtel, Philipp L Müller, Isabel Faust

Br J Ophthalmol· August 2020

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Blood Serum Stimulates p38-Mediated Proliferation and Changes in Global Gene Expression of Adult Human Cardiac Stem Cells.
Anna L Höving, Kazuko E Schmidt, Madlen Merten, Jassin Hamidi, Ann-Katrin Rott, Isabel Faust

Cells· June 2020

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Cellular and Molecular Biomarkers Indicate Premature Aging in Pseudoxanthoma Elasticum Patients.
Janina Tiemann, Thomas Wagner, Olivier M Vanakker, Matthias van Gils, José-Luis Bueno Cabrera, Isabel Faust

Aging Dis· May 2020

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Activin A-Mediated Regulation of XT-I in Human Skin Fibroblasts.
Thanh-Diep Ly, Ricarda Plümers, Bastian Fischer, Vanessa Schmidt, Doris Hendig, Isabel Faust

Biomolecules· April 2020

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microRNA-145 mediates xylosyltransferase-I induction in myofibroblasts via suppression of transcription factor KLF4.
Thanh-Diep Ly, Lara Riedel, Bastian Fischer, Vanessa Schmidt, Doris Hendig, Isabel Faust

Biochem Biophys Res Commun· March 2020

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Xylosyltransferase-deficient human HEK293 cells show a strongly reduced proliferation capacity and viability.
Bastian Fischer, Thanh-Diep Ly, Vanessa Schmidt, Doris Hendig, Joachim Kuhn, Isabel Faust

Biochem Biophys Res Commun· January 2020

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Acute Retinopathy in Pseudoxanthoma Elasticum.
Martin Gliem, Johannes Birtel, Philipp L Müller, Doris Hendig, Isabel Faust

JAMA Ophthalmol· October 2019

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First description of a compensatory xylosyltransferase I induction observed after an antifibrotic UDP-treatment of normal human dermal fibroblasts.
Bastian Fischer, Thanh-Diep Ly, Doris Hendig, Joachim Kuhn, Eve-Isabelle Pécheur, Isabel Faust

Biochem Biophys Res Commun· April 2019

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Abcc6 deficiency in mice leads to altered ABC transporter gene expression in metabolic active tissues.
Bettina Ibold, Isabel Faust, Janina Tiemann, Theo G M F Gorgels, Arthur A B Bergen

Lipids Health Dis· January 2019

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microRNA-29b mediates fibrotic induction of human xylosyltransferase-I in human dermal fibroblasts via the Sp1 pathway.
Lara Riedel, Bastian Fischer, Thanh-Diep Ly, Doris Hendig, Joachim Kuhn, Isabel Faust

Sci Rep· December 2018

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Measurement of apixaban, dabigatran, edoxaban and rivaroxaban in human plasma using automated online solid-phase extraction combined with ultra-performance liquid chromatography-tandem mass spectrometry and its comparison with coagulation assays.
Joachim Kuhn, Tatjana Gripp, Tobias Flieder, Andreas Hammerschmidt, Doris Hendig, Isabel Faust

Clin Chim Acta· November 2018

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Characterization of dermal myofibroblast differentiation in pseudoxanthoma elasticum.
Isabel Faust, Elfi Donhauser, Bastian Fischer, Bettina Ibold, Joachim Kuhn

Exp Cell Res· November 2017

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Large-scaled metabolic profiling of human dermal fibroblasts derived from pseudoxanthoma elasticum patients and healthy controls.
Patricia Kuzaj, Joachim Kuhn, Ryan D Michalek, Edward D Karoly, Isabel Faust

PLoS One· November 2015

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Human xylosyltransferases--mediators of arthrofibrosis? New pathomechanistic insights into arthrofibrotic remodeling after knee replacement therapy.
Isabel Faust, Philipp Traut, Frank Nolting, Jan Petschallies, Elena Neumann

Sci Rep· July 2015

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Xylosyltransferase II is the predominant isoenzyme which is responsible for the steady-state level of xylosyltransferase activity in human serum.
Joachim Kuhn, Christian Götting, Brendan J Beahm, Carolyn R Bertozzi, Isabel Faust

Biochem Biophys Res Commun· April 2015

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Identification and characterization of human xylosyltransferase II promoter single nucleotide variants.
Isabel Faust, Kai Oliver Böker, Christina Eirich, Dagmar Akkermann, Joachim Kuhn

Biochem Biophys Res Commun· March 2015

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First description of the complete human xylosyltransferase-I promoter region.
Isabel Faust, Kai Oliver Böker, Christoph Lichtenberg, Joachim Kuhn, Cornelius Knabbe

BMC Genet· December 2014

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ABCC6- a new player in cellular cholesterol and lipoprotein metabolism?
Patricia Kuzaj, Joachim Kuhn, Mareike Dabisch-Ruthe, Isabel Faust, Christian Götting

Lipids Health Dis· July 2014

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Measurement of HMG CoA reductase activity in different human cell lines by ultra-performance liquid chromatography tandem mass spectrometry.
Patricia Kuzaj, Joachim Kuhn, Isabel Faust, Cornelius Knabbe, Doris Hendig

Biochem Biophys Res Commun· January 2014

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