Publications by authors named "Ryan D Michalek"

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Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters.
Samit Ganguly, David Finkelstein, Timothy I Shaw, Ryan D Michalek, Kimberly M Zorn

PLoS One· November 2021

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Replicatively senescent human fibroblasts reveal a distinct intracellular metabolic profile with alterations in NAD+ and nicotinamide metabolism.
Emma L James, James A E Lane, Ryan D Michalek, Edward D Karoly, E Kenneth Parkinson

Sci Rep· December 2016

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Oxidative Stress and Metabolic Perturbations in Wooden Breast Disorder in Chickens.
Behnam Abasht, Marie F Mutryn, Ryan D Michalek, William R Lee

PLoS One· September 2016

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Large-scaled metabolic profiling of human dermal fibroblasts derived from pseudoxanthoma elasticum patients and healthy controls.
Patricia Kuzaj, Joachim Kuhn, Ryan D Michalek, Edward D Karoly, Isabel Faust

PLoS One· November 2015

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Women at extreme risk for obesity-related carcinogenesis: Baseline endometrial pathology and impact of bariatric surgery on weight, metabolic profiles and quality of life.
Susan C Modesitt, Peter T Hallowell, Jill K Slack-Davis, Ryan D Michalek, Kristen A Atkins

Gynecol Oncol· August 2015

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Transmissible microbial and metabolomic remodeling by soluble dietary fiber improves metabolic homeostasis.
Baokun He, Kazunari Nohara, Nadim J Ajami, Ryan D Michalek, Xiangjun Tian

Sci Rep· June 2015

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Corrigendum: Landscape of the mitochondrial Hsp90 metabolome in tumours.
Young Chan Chae, Alessia Angelin, Sofia Lisanti, Andrew V Kossenkov, Kaye D Speicher, Ryan D Michalek

Nat Commun· June 2015

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Senescent human fibroblasts show increased glycolysis and redox homeostasis with extracellular metabolomes that overlap with those of irreparable DNA damage, aging, and disease.
Emma L James, Ryan D Michalek, Gayani N Pitiyage, Alice M de Castro, Katie S Vignola

J Proteome Res· April 2015

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Adaptive mitochondrial reprogramming and resistance to PI3K therapy.
Jagadish C Ghosh, Markus D Siegelin, Valentina Vaira, Alice Faversani, Michele Tavecchio, Ryan D Michalek

J Natl Cancer Inst· March 2015

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Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics.
Joseph G Crompton, Madhusudhanan Sukumar, Rahul Roychoudhuri, David Clever, Alena Gros, Ryan D Michalek

Cancer Res· January 2015

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Metabolomic profiles and childhood obesity.
Wei Perng, Matthew W Gillman, Abby F Fleisch, Ryan D Michalek, Steven M Watkins

Obesity (Silver Spring)· December 2014

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Increased cell surface free thiols identify effector CD8+ T cells undergoing T cell receptor stimulation.
Samuel Troy Pellom, Ryan D Michalek, Katie E Crump, P Kent Langston, Daniel G Juneau

PLoS One· July 2014

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The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function.
Andrew N Macintyre, Valerie A Gerriets, Amanda G Nichols, Ryan D Michalek, Michael C Rudolph

Cell Metab· July 2014

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Landscape of the mitochondrial Hsp90 metabolome in tumours.
Young Chan Chae, Alessia Angelin, Sofia Lisanti, Andrew V Kossenkov, Kaye D Speicher, Ryan D Michalek

Nat Commun· January 2014

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Metabolic regulation of T lymphocytes.
Nancie J MacIver, Ryan D Michalek, Jeffrey C Rathmell

Annu Rev Immunol· June 2013

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Peroxiredoxin II regulates effector and secondary memory CD8+ T cell responses.
Ryan D Michalek, Katie E Crump, Ashley E Weant, Elizabeth M Hiltbold, Daniel G Juneau

J Virol· December 2012

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Defects in apoptosis increase memory CD8+ T cells following infection of Bim-/-Faslpr/lpr mice.
Ashley E Weant, Ryan D Michalek, Katie E Crump, Chun Liu, Andrew P Konopitski

Cell Immunol· December 2011

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The oxysterol, 27-hydroxycholesterol, links cholesterol metabolism to bone homeostasis through its actions on the estrogen and liver X receptors.
Erik R Nelson, Carolyn D DuSell, Xiaojuan Wang, Matthew K Howe, Glenda Evans, Ryan D Michalek

Endocrinology· December 2011

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Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation.
Ryan D Michalek, Valerie A Gerriets, Amanda G Nichols, Makoto Inoue, Dmitri Kazmin

Proc Natl Acad Sci U S A· November 2011

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Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.
Ryan D Michalek, Valerie A Gerriets, Sarah R Jacobs, Andrew N Macintyre, Nancie J MacIver

J Immunol· March 2011

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The metabolic life and times of a T-cell.
Ryan D Michalek, Jeffrey C Rathmell

Immunol Rev· July 2010

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IL-7 is essential for homeostatic control of T cell metabolism in vivo.
Sarah R Jacobs, Ryan D Michalek, Jeffrey C Rathmell

J Immunol· April 2010

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The angiotensin II-AT1 receptor stimulates reactive oxygen species within the cell nucleus.
Karl D Pendergrass, Tanya M Gwathmey, Ryan D Michalek, Jason M Grayson, Mark C Chappell

Biochem Biophys Res Commun· June 2009

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Methed-up FOXOs can't in-Akt-ivate.
Ryan D Michalek, Jeffrey C Rathmell

Mol Cell· October 2008

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The requirement of reactive oxygen intermediates for lymphocytic choriomeningitis virus binding and growth.
Ryan D Michalek, S Troy Pellom, Beth C Holbrook, Jason M Grayson

Virology· September 2008

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