Publications by authors named "Isabel Jaco"

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Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers.
Stephane Ferretti, Jacques Hamon, Ruben de Kanter, Clemens Scheufler, Rita Andraos-Rey, Isabel Jaco

Nature· May 2024

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The anticonvulsive Phenhydan suppresses extrinsic cell death.
Caroline Moerke, Isabel Jaco, Christin Dewitz, Tammo Müller, Annette V Jacobsen

Cell Death Differ· September 2019

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SUMO-mediated regulation of NLRP3 modulates inflammasome activity.
Rachael Barry, Sidonie Wicky John, Gianmaria Liccardi, Tencho Tenev, Isabel Jaco

Nat Commun· August 2018

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Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic Potential.
Rebecca Feltham, Kunzah Jamal, Tencho Tenev, Gianmaria Liccardi, Isabel Jaco

Cell Rep· April 2018

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MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death.
Isabel Jaco, Alessandro Annibaldi, Najoua Lalaoui, Rebecca Wilson, Tencho Tenev

Mol Cell· June 2017

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BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping.
Sophie Badie, Jose M Escandell, Peter Bouwman, Ana Rita Carlos, Maria Thanasoula, Isabel Jaco

Nat Struct Mol Biol· December 2010

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A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases.
Roberta Benetti, Susana Gonzalo, Isabel Jaco, Purificación Muñoz, Susana Gonzalez

Nat Struct Mol Biol· September 2008

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Centromere mitotic recombination in mammalian cells.
Isabel Jaco, Andrés Canela, Elsa Vera, Maria A Blasco

J Cell Biol· June 2008

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A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases.
Roberta Benetti, Susana Gonzalo, Isabel Jaco, Purificación Muñoz, Susana Gonzalez

Nat Struct Mol Biol· March 2008

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Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination.
Roberta Benetti, Susana Gonzalo, Isabel Jaco, Gunnar Schotta, Peter Klatt

J Cell Biol· September 2007

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Global chromatin compaction limits the strength of the DNA damage response.
Matilde Murga, Isabel Jaco, Yuhong Fan, Rebeca Soria, Barbara Martinez-Pastor

J Cell Biol· September 2007

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DNA methyltransferases control telomere length and telomere recombination in mammalian cells.
Susana Gonzalo, Isabel Jaco, Mario F Fraga, Taiping Chen, En Li

Nat Cell Biol· April 2006

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Postreplicative joining of DNA double-strand breaks causes genomic instability in DNA-PKcs-deficient mouse embryonic fibroblasts.
Marta Martín, Anna Genescà, Laura Latre, Isabel Jaco, Guillermo E Taccioli

Cancer Res· November 2005

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Role of human Ku86 in telomere length maintenance and telomere capping.
Isabel Jaco, Purificación Muñoz, María A Blasco

Cancer Res· October 2004

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Functional interaction between poly(ADP-Ribose) polymerase 2 (PARP-2) and TRF2: PARP activity negatively regulates TRF2.
Françoise Dantzer, Marie-Josèphe Giraud-Panis, Isabel Jaco, Jean-Christophe Amé, Inès Schultz

Mol Cell Biol· February 2004

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Role of mammalian Rad54 in telomere length maintenance.
Isabel Jaco, Purificación Muñoz, Fermín Goytisolo, Joanna Wesoly, Susan Bailey

Mol Cell Biol· August 2003

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