Publications by authors named "Isabel M Pires"

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Investigating the impact of the interstitial fluid flow and hypoxia interface on cancer transcriptomes using a spheroid-on-chip perfusion system.
Emily Pyne, Mark Reardon, Martin Christensen, Pablo Rodriguez Mateos, Scott Taylor, Isabel M Pires

Lab Chip· September 2024

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Exploring hypoxic biology to improve radiotherapy outcomes.
Chun Li, Lucy Wiseman, Ene Okoh, Michael Lind, Rajarshi Roy, Isabel M Pires

Expert Rev Mol Med· April 2022

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Predicting personalised and progressive adaptive dose escalation to gross tumour volume using knowledge-based planning models for inoperable advanced-stage non-small cell lung cancer patients treated with volumetric modulated arc therapy.
Nilesh S Tambe, Isabel M Pires, Craig Moore, Andrew Wieczorek, Sunil Upadhyay

Biomed Phys Eng Express· March 2022

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The Role of Glucosinolates from Cruciferous Vegetables (Brassicaceae) in Gastrointestinal Cancers: From Prevention to Therapeutics.
Catarina Melim, Maria R Lauro, Isabel M Pires, Paulo J Oliveira, Célia Cabral

Pharmaceutics· January 2022

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Practical Considerations of Dissolved Oxygen Levels for Platelet Function under Hypoxia.
Branden Kusanto, Andrew Gordon, Leigh Naylor-Adamson, Lloyd Atkinson, Charlie Coupland, Isabel M Pires

Int J Mol Sci· December 2021

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Polypoidal Choroidal Vasculopathy in Caucasians: Morphological Findings from Multimodal Retinal Imaging.
Jorge M Simão, Cláudia V Farinha, João P Marques, Sandrina Nunes, Isabel M Pires

Ophthalmologica· September 2021

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Validation of in-house knowledge-based planning model for predicting change in target coverage during VMAT radiotherapy to in-operable advanced-stage NSCLC patients.
Nilesh S Tambe, Isabel M Pires, Craig Moore, Andrew Wieczorek, Sunil Upadhyay

Biomed Phys Eng Express· September 2021

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Predicting personalised optimal arc parameter using knowledge-based planning model for inoperable locally advanced lung cancer patients to reduce organ at risk doses.
Nilesh S Tambe, Isabel M Pires, Craig Moore, Andrew Wieczorek, Sunil Upadhyay

Biomed Phys Eng Express· September 2021

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Spheroid-on-chip microfluidic technology for the evaluation of the impact of continuous flow on metastatic potential in cancer models .
Thomas Collins, Emily Pyne, Martin Christensen, Alexander Iles, Nicole Pamme, Isabel M Pires

Biomicrofluidics· July 2021

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Cytotoxic effects of Ridolfia segetum (L.) Moris phytoproducts in cancer cells.
Ellie Beeby, Mariana Magalhães, Marco F L Lemos, Isabel M Pires, Célia Cabral

J Ethnopharmacol· March 2021

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PI3K inhibition as a novel therapeutic strategy for neoadjuvant chemoradiotherapy resistant oesophageal adenocarcinoma.
Sarah D Edge, Isaline Renard, Emily Pyne, Chun Li, Hannah Moody, Isabel M Pires

Br J Radiol· March 2021

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Editorial: Advances in Cancer Stem Cell Biology.
Deema Hussein, Isabel M Pires, Petra Krause, Hans-Juergen Schulten

Front Genet· March 2021

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Secondary metabolites (essential oils) from sand-dune plants induce cytotoxic effects in cancer cells.
Ellie Beeby, Mariana Magalhães, Juliana Poças, Thomas Collins, Marco F L Lemos, Isabel M Pires

J Ethnopharmacol· August 2020

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Validation of in-house knowledge-based planning model for advance-stage lung cancer patients treated using VMAT radiotherapy.
Nilesh S Tambe, Isabel M Pires, Craig Moore, Christopher Cawthorne, Andrew W Beavis

Br J Radiol· February 2020

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Natural Products as a Source for New Leads in Cancer Research and Treatment.
Célia Cabral, Thomas Efferth, Isabel M Pires, Patricia Severino, Marco F L Lemos

Evid Based Complement Alternat Med· July 2018

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WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer.
Flore-Anne Poujade, Aarren Mannion, Nicholas Brittain, Andrew Theodosi, Ellie Beeby, Isabel M Pires

Br J Cancer· May 2018

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HIF-1α-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion.
Isabel M Pires, Nina Jg Blokland, Agnieke Wt Broos, Flore-Anne Poujade, Joana M Senra

Cancer Biol Ther· October 2014

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Use of the xCELLigence system for real-time analysis of changes in cellular motility and adhesion in physiological conditions.
Simon Scrace, Eric O'Neill, Ester M Hammond, Isabel M Pires

Methods Mol Biol· February 2014

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Replication stress and chromatin context link ATM activation to a role in DNA replication.
Monica M Olcina, Iosifina P Foskolou, Selvakumar Anbalagan, Joana M Senra, Isabel M Pires

Mol Cell· December 2013

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CH-01 is a hypoxia-activated prodrug that sensitizes cells to hypoxia/reoxygenation through inhibition of Chk1 and Aurora A.
Cindy Cazares-Körner, Isabel M Pires, I Diane Swallow, Samuel C Grayer, Liam J O'Connor

ACS Chem Biol· July 2013

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Radiosensitization of renal cell carcinoma in vitro through the induction of autophagy.
Selvakumar Anbalagan, Isabel M Pires, Christopher Blick, Mark A Hill, David J P Ferguson

Radiother Oncol· June 2012

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Contextual synthetic lethality of cancer cell kill based on the tumor microenvironment.
Norman Chan, Isabel M Pires, Zuzana Bencokova, Carla Coackley, Kaisa R Luoto

Cancer Res· October 2010

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Exposure to acute hypoxia induces a transient DNA damage response which includes Chk1 and TLK1.
Isabel M Pires, Zuzana Bencokova, Chris McGurk, Ester M Hammond

Cell Cycle· July 2010

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Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability.
Isabel M Pires, Zuzana Bencokova, Manuela Milani, Lisa K Folkes, Ji-Liang Li

Cancer Res· February 2010

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ATM activation and signaling under hypoxic conditions.
Zuzana Bencokova, Muriel R Kaufmann, Isabel M Pires, Philip S Lecane, Amato J Giaccia

Mol Cell Biol· January 2009

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