Publications by authors named "Simon Scrace"

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Morphological map of under- and overexpression of genes in human cells.
Srinivas Niranj Chandrasekaran, Eric Alix, John Arevalo, Adriana Borowa, Patrick J Byrne, Simon Scrace

Nat Methods· August 2025

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RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis.
Maria Laura Tognoli, Nikola Vlahov, Sander Steenbeek, Anna M Grawenda, Michael Eyres, Simon Scrace

EMBO J· October 2021

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Disruption of tumour-host communication by downregulation of LFA-1 reduces COX-2 and e-NOS expression and inhibits brain metastasis growth.
Manuel Sarmiento Soto, Emma R O'Brien, Kleopatra Andreou, Simon F Scrace, Rasheed Zakaria

Oncotarget· August 2016

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TGF-β Targets the Hippo Pathway Scaffold RASSF1A to Facilitate YAP/SMAD2 Nuclear Translocation.
Dafni-Eleftheria Pefani, Daniela Pankova, Aswin G Abraham, Anna M Grawenda, Nikola Vlahov, Simon Scrace

Mol Cell· July 2016

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Alternate RASSF1 Transcripts Control SRC Activity, E-Cadherin Contacts, and YAP-Mediated Invasion.
Nikola Vlahov, Simon Scrace, Manuel Sarmiento Soto, Anna M Grawenda, Leanne Bradley

Curr Biol· December 2015

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Identification of novel, in vivo active Chk1 inhibitors utilizing structure guided drug design.
Andrew J Massey, Stephen Stokes, Helen Browne, Nicolas Foloppe, Andreá Fiumana, Simon Scrace

Oncotarget· November 2015

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Use of the xCELLigence system for real-time analysis of changes in cellular motility and adhesion in physiological conditions.
Simon Scrace, Eric O'Neill, Ester M Hammond, Isabel M Pires

Methods Mol Biol· February 2014

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RASSF Signalling and DNA Damage: Monitoring the Integrity of the Genome?
Simon F Scrace, Eric O'Neill

Mol Biol Int· August 2012

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Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution.
Andrew Potter, Victoria Oldfield, Claire Nunns, Christophe Fromont, Stuart Ray, Simon F Scrace

Bioorg Med Chem Lett· November 2010

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Structure-guided design of alpha-amino acid-derived Pin1 inhibitors.
Andrew J Potter, Stuart Ray, Louisa Gueritz, Claire L Nunns, Christopher J Bryant, Simon F Scrace

Bioorg Med Chem Lett· January 2010

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ATM regulates a RASSF1A-dependent DNA damage response.
Garth Hamilton, Karen S Yee, Simon Scrace, Eric O'Neill

Curr Biol· December 2009

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Transient treatment with CDK inhibitors eliminates proliferative potential even when their abilities to evoke apoptosis and DNA damage are blocked.
Simon F Scrace, Peter Kierstan, Jenifer Borgognoni, Lan-Zhen Wang, Sarah Denny

Cell Cycle· December 2008

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