Publications by authors named "Isabelle Aubry"

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Leishmania donovani's protein tyrosine phosphatases interact with DUF21 and respond to environmental magnesium.
Kayla Paulini, Hira Khursheed, Wen Wei Zhang, Isabelle Aubry, Greg Matlashewski

FEBS J· October 2025

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Uncovering the individual immunotherapeutic roles of PTPN1 and PTPN2 in T cells during dual inhibition.
Luis-Alberto Perez-Quintero, Alexandre J Poirier, Chu-Han Feng, Zuzet Martinez-Cordova, Isabelle Aubry

iScience· October 2025

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PTPN2 Negatively Regulates Macrophage Immune Responses and Cellular Bioenergetics.
Valerie Vinette, Yevgen Zolotarov, Alexandre Poirier, Zuzet Martinez Cordova, Isabelle Aubry

FASEB J· May 2025

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PTPN1/2 inhibition promotes muscle stem cell differentiation in Duchenne muscular dystrophy.
Yiyang Liu, Shulei Li, Rebecca Robertson, Jules A Granet, Isabelle Aubry

Life Sci Alliance· January 2025

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An HuR mutant, HuR-V225I, identified in adult T-cell Leukemia/Lymphoma, alters the pro-apoptotic function of HuR.
Bianca Colalillo, Sujitha Sali, Ali H Aldouhki, Isabelle Aubry, Sergio Di Marco

Cell Death Discov· December 2024

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PTPRS is a novel marker for early Tau pathology and synaptic integrity in Alzheimer's disease.
Alexandre Poirier, Cynthia Picard, Anne Labonté, Isabelle Aubry, Daniel Auld

Sci Rep· June 2024

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PTPRS is a novel marker for early tau pathology and synaptic integrity in Alzheimer's disease.
Alexandre Poirier, Cynthia Picard, Anne Labonté, Isabelle Aubry, Daniel Auld

bioRxiv· May 2024

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The induction of SHP-1 degradation by TAOK3 ensures the responsiveness of T cells to TCR stimulation.
Alexandre Poirier, João Vitor Silva Ormonde, Isabelle Aubry, Belma Melda Abidin, Chu-Han Feng

Sci Signal· January 2024

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PRL-1/2 phosphatases control TRPM7 magnesium-dependent function to regulate cellular bioenergetics.
Serge Hardy, Yevgen Zolotarov, Jacob Coleman, Simon Roitman, Hira Khursheed, Isabelle Aubry

Proc Natl Acad Sci U S A· April 2023

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Brief exposure of neuronal cells to levels of SCFAs observed in human systemic circulation impair lipid metabolism resulting in apoptosis.
Tiffany A Fillier, Shrushti Shah, Karen M Doody, Thu H Pham, Isabelle Aubry

Sci Rep· August 2022

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Protein tyrosine phosphatome metabolic screen identifies TC-PTP as a positive regulator of cancer cell bioenergetics and mitochondrial dynamics.
Valerie Vinette, Isabelle Aubry, Hayley Insull, Noriko Uetani, Serge Hardy

FASEB J· July 2021

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Impact of intravitreal aflibercept dosing regimens in treatment-naïve patients with neovascular age-related macular degeneration in routine clinical practice in France: results from the RAINBOW study.
Michel Weber, Laurent Kodjikian, Florence Coscas, Céline Faure, Isabelle Aubry

BMJ Open Ophthalmol· April 2020

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Effectiveness and safety of intravitreal aflibercept in patients with wet age-related macular degeneration treated in routine clinical practices across France: 12-month outcomes of the RAINBOW study.
Michel Weber, Laurent Velasque, Florence Coscas, Céline Faure, Isabelle Aubry

BMJ Open Ophthalmol· April 2019

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Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity.
Mattias Nd Svensson, Karen M Doody, Benjamin J Schmiedel, Sourya Bhattacharyya, Bharat Panwar, Isabelle Aubry

J Clin Invest· March 2019

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Loss of T-cell protein tyrosine phosphatase in the intestinal epithelium promotes local inflammation by increasing colonic stem cell proliferation.
Stéphanie Bussières-Marmen, Valérie Vinette, Jeremy Gungabeesoon, Isabelle Aubry, Luis Alberto Pérez-Quintero

Cell Mol Immunol· April 2018

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Identification of function-regulating antibodies targeting the receptor protein tyrosine phosphatase sigma ectodomain.
Chia-Lun Wu, Serge Hardy, Isabelle Aubry, Melissa Landry, Allison Haggarty

PLoS One· October 2017

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PTP1B Deficiency Enables the Ability of a High-Fat Diet to Drive the Invasive Character of PTEN-Deficient Prostate Cancers.
David P Labbé, Noriko Uetani, Valérie Vinette, Laurent Lessard, Isabelle Aubry

Cancer Res· June 2016

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Identification of Bidentate Salicylic Acid Inhibitors of PTP1B.
Sina Haftchenary, Andriana O Jouk, Isabelle Aubry, Andrew M Lewis, Melissa Landry

ACS Med Chem Lett· September 2015

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UBC9-dependent association between calnexin and protein tyrosine phosphatase 1B (PTP1B) at the endoplasmic reticulum.
Dukgyu Lee, Allison Kraus, Daniel Prins, Jody Groenendyk, Isabelle Aubry

J Biol Chem· February 2015

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Allosteric noncompetitive small molecule selective inhibitors of CD45 tyrosine phosphatase suppress T-cell receptor signals and inflammation in vivo.
Michael D Perron, Shafinaz Chowdhury, Isabelle Aubry, Enrico Purisima, Michel L Tremblay

Mol Pharmacol· April 2014

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An RNA aptamer that selectively inhibits the enzymatic activity of protein tyrosine phosphatase 1B in vitro.
Brent Townshend, Isabelle Aubry, Richard C Marcellus, Kalle Gehring, Michel L Tremblay

Chembiochem· July 2010

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Altered mineralization of human osteoarthritic osteoblasts is attributable to abnormal type I collagen production.
Denis Couchourel, Isabelle Aubry, Aline Delalandre, Martin Lavigne, Johanne Martel-Pelletier

Arthritis Rheum· May 2009

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Lipidyl pseudopteranes A-F: isolation, biomimetic synthesis, and PTP1B inhibitory activity of a new class of pseudopteranoids from the Gorgonian Pseudopterogorgia acerosa.
Abhijeet S Kate, Isabelle Aubry, Michel L Tremblay, Russell G Kerr

J Nat Prod· December 2008

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Abnormal insulin-like growth factor 1 signaling in human osteoarthritic subchondral bone osteoblasts.
Frédéric Massicotte, Isabelle Aubry, Johanne Martel-Pelletier, Jean-Pierre Pelletier, Julio Fernandes

Arthritis Res Ther· February 2007

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Cellular inhibition of protein tyrosine phosphatase 1B by uncharged thioxothiazolidinone derivatives.
Matthew Stuible, Liang Zhao, Isabelle Aubry, Dirk Schmidt-Arras, Frank-D Böhmer

Chembiochem· January 2007

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