Publications by authors named "Isabelle Gagnon-Arsenault"

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FungAMR: a comprehensive database for investigating fungal mutations associated with antimicrobial resistance.
Camille Bédard, Alicia Pageau, Anna Fijarczyk, David Mendoza-Salido, Alejandro J Alcañiz, Isabelle Gagnon-Arsenault

Nat Microbiol· September 2025

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Most azole resistance mutations in the Candida albicans drug target confer cross-resistance without intrinsic fitness cost.
Camille Bédard, Isabelle Gagnon-Arsenault, Jonathan Boisvert, Samuel Plante, Alexandre K Dubé

Nat Microbiol· November 2024

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Hybrid adaptation is hampered by Haldane's sieve.
Carla Bautista, Isabelle Gagnon-Arsenault, Mariia Utrobina, Anna Fijarczyk, Devin P Bendixsen

Nat Commun· November 2024

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The putative error prone polymerase mediates DNA damage and drug resistance in .
Michelle R Agyare-Tabbi, Deeva Uthayakumar, Desiree Francis, Laetitia Maroc, Chris Grant, Isabelle Gagnon-Arsenault

NPJ Antimicrob Resist· November 2024

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The substrate quality of CK2 target sites has a determinant role on their function and evolution.
David Bradley, Chantal Garand, Hugo Belda, Isabelle Gagnon-Arsenault, Moritz Treeck

Cell Syst· June 2024

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Deep mutational scanning of Pneumocystis jirovecii dihydrofolate reductase reveals allosteric mechanism of resistance to an antifolate.
Francois D Rouleau, Alexandre K Dubé, Isabelle Gagnon-Arsenault, Soham Dibyachintan, Alicia Pageau

PLoS Genet· April 2024

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Parallel Nonfunctionalization of CK1δ/ε Kinase Ohnologs Following a Whole-Genome Duplication Event.
Daniel Evans-Yamamoto, Alexandre K Dubé, Gourav Saha, Samuel Plante, David Bradley, Isabelle Gagnon-Arsenault

Mol Biol Evol· December 2023

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Parallel nonfunctionalization of CK1δ/ε kinase ohnologs following a whole-genome duplication event.
Daniel Evans-Yamamoto, Alexandre K Dubé, Gourav Saha, Samuel Plante, David Bradley, Isabelle Gagnon-Arsenault

bioRxiv· October 2023

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Evolutionary Trajectories are Contingent on Mitonuclear Interactions.
Damien Biot-Pelletier, Stefano Bettinazzi, Isabelle Gagnon-Arsenault, Alexandre K Dubé, Camille Bédard

Mol Biol Evol· April 2023

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Epistasis between promoter activity and coding mutations shapes gene evolvability.
Angel F Cisneros, Isabelle Gagnon-Arsenault, Alexandre K Dubé, Philippe C Després, Pradum Kumar

Sci Adv· February 2023

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Frequent Assembly of Chimeric Complexes in the Protein Interaction Network of an Interspecies Yeast Hybrid.
Rohan Dandage, Caroline M Berger, Isabelle Gagnon-Arsenault, Kyung-Mee Moon, Richard Greg Stacey

Mol Biol Evol· April 2021

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Expression attenuation as a mechanism of robustness against gene duplication.
Diana Ascencio, Guillaume Diss, Isabelle Gagnon-Arsenault, Alexandre K Dubé, Alexander DeLuna

Proc Natl Acad Sci U S A· February 2021

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The role of structural pleiotropy and regulatory evolution in the retention of heteromers of paralogs.
Axelle Marchant, Angel F Cisneros, Alexandre K Dubé, Isabelle Gagnon-Arsenault, Diana Ascencio

Elife· August 2019

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A collection of barcoded natural isolates of Saccharomyces paradoxus to study microbial evolutionary ecology.
Clara Bleuven, Alexandre K Dubé, Guillaume Q Nguyen, Isabelle Gagnon-Arsenault, Hélène Martin

Microbiologyopen· July 2019

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Turnover of ribosome-associated transcripts from de novo ORFs produces gene-like characteristics available for de novo gene emergence in wild yeast populations.
Éléonore Durand, Isabelle Gagnon-Arsenault, Johan Hallin, Isabelle Hatin, Alexandre K Dubé

Genome Res· June 2019

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Extended linkers improve the detection of protein-protein interactions (PPIs) by dihydrofolate reductase protein-fragment complementation assay (DHFR PCA) in living cells.
Andrée-Ève Chrétien, Isabelle Gagnon-Arsenault, Alexandre K Dubé, Xavier Barbeau, Philippe C Després

Mol Cell Proteomics· March 2018

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Extended Linkers Improve the Detection of Protein-protein Interactions (PPIs) by Dihydrofolate Reductase Protein-fragment Complementation Assay (DHFR PCA) in Living Cells.
Andrée-Ève Chrétien, Isabelle Gagnon-Arsenault, Alexandre K Dubé, Xavier Barbeau, Philippe C Després

Mol Cell Proteomics· February 2018

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Deep transcriptome annotation enables the discovery and functional characterization of cryptic small proteins.
Sondos Samandi, Annie V Roy, Vivian Delcourt, Jean-François Lucier, Jules Gagnon, Isabelle Gagnon-Arsenault

Elife· October 2017

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Gene duplication can impart fragility, not robustness, in the yeast protein interaction network.
Guillaume Diss, Isabelle Gagnon-Arsenault, Anne-Marie Dion-Coté, Hélène Vignaud, Diana I Ascencio

Science· February 2017

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Evolutionary rescue by compensatory mutations is constrained by genomic and environmental backgrounds.
Marie Filteau, Véronique Hamel, Marie-Christine Pouliot, Isabelle Gagnon-Arsenault, Alexandre K Dubé

Mol Syst Biol· October 2015

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Systematic identification of signal integration by protein kinase A.
Marie Filteau, Guillaume Diss, Francisco Torres-Quiroz, Alexandre K Dubé, Andrea Schraffl, Isabelle Gagnon-Arsenault

Proc Natl Acad Sci U S A· April 2015

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N-terminal entrance loop of yeast Yps1 and O-glycosylation of substrates are determinant factors controlling the shedding activity of this GPI-anchored endopeptidase.
Alexandre K Dubé, Marc Bélanger, Isabelle Gagnon-Arsenault, Yves Bourbonnais

BMC Microbiol· February 2015

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Detecting functional divergence after gene duplication through evolutionary changes in posttranslational regulatory sequences.
Alex N Nguyen Ba, Bob Strome, Jun Jie Hua, Jonathan Desmond, Isabelle Gagnon-Arsenault

PLoS Comput Biol· December 2014

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Modulation of the yeast protein interactome in response to DNA damage.
Samuel Rochette, Isabelle Gagnon-Arsenault, Guillaume Diss, Christian R Landry

J Proteomics· April 2014

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A systematic approach for the genetic dissection of protein complexes in living cells.
Guillaume Diss, Alexandre K Dubé, Joël Boutin, Isabelle Gagnon-Arsenault, Christian R Landry

Cell Rep· June 2013

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