Publications by authors named "Moritz Treeck"

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Toxoplasma effector TgROP1 establishes membrane contact sites with the endoplasmic reticulum during infection.
Chahat Mehra, Jesús Alvarado Valverde, Ana Margarida Nogueira Matias, Francesca Torelli, Tânia Catarina Medeiros, Moritz Treeck

Nat Microbiol· December 2025

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Publisher Correction: Toxoplasma effector TgROP1 establishes membrane contact sites with the endoplasmic reticulum during infection.
Chahat Mehra, Jesús Alvarado Valverde, Ana Margarida Nogueira Matias, Francesca Torelli, Tânia Catarina Medeiros, Moritz Treeck

Nat Microbiol· December 2025

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The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound.
Hugo Belda, David Bradley, Evangelos Christodoulou, Stephanie D Nofal, Malgorzata Broncel, Moritz Treeck

Nat Microbiol· June 2025

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GRA12 is a common virulence factor across Toxoplasma gondii strains and mouse subspecies.
Francesca Torelli, Simon Butterworth, Eloise Lockyer, Ana N Matias, Franziska Hildebrandt, Moritz Treeck

Nat Commun· April 2025

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A CRISPR view on genetic screens in Toxoplasma gondii.
Franziska Hildebrandt, Ana N Matias, Moritz Treeck

Curr Opin Microbiol· February 2025

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Paracrine rescue of MYR1-deficient mutants reveals limitations of pooled CRISPR screens.
Francesca Torelli, Diogo M da Fonseca, Simon W Butterworth, Joanna C Young, Moritz Treeck

Elife· December 2024

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PfHDAC1 is an essential regulator of asexual proliferation and host cell invasion genes with a dynamic genomic occupancy responsive to artemisinin stress.
Abhishek Kanyal, Bhagyashree Deshmukh, Heledd Davies, D V Mamatharani, Dilsha Farheen, Moritz Treeck

mBio· June 2024

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The substrate quality of CK2 target sites has a determinant role on their function and evolution.
David Bradley, Chantal Garand, Hugo Belda, Isabelle Gagnon-Arsenault, Moritz Treeck

Cell Syst· June 2024

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Expression of the MSPDBL2 antigen in a discrete subset of schizonts is regulated by GDV1 but may not be linked to sexual commitment.
Aline Freville, Lindsay B Stewart, Kevin K A Tetteh, Moritz Treeck, Alfred Cortes

mBio· May 2024

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A screen for Plasmodium falciparum sporozoite surface protein binding to human hepatocyte surface receptors identifies novel host-pathogen interactions.
Rameswara R Segireddy, Hugo Belda, Annie S P Yang, Kirsten Dundas, Julia Knoeckel, Moritz Treeck

Malar J· May 2024

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Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in .
Alex W Chan, Malgorzata Broncel, Eden Yifrach, Nicole R Haseley, Sundeep Chakladar, Moritz Treeck

Elife· November 2023

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High-throughput identification of Toxoplasma gondii effector proteins that target host cell transcription.
Simon Butterworth, Kristina Kordova, Sambamurthy Chandrasekaran, Kaitlin K Thomas, Francesca Torelli, Moritz Treeck

Cell Host Microbe· October 2023

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PerTurboID, a targeted in situ method reveals the impact of kinase deletion on its local protein environment in the cytoadhesion complex of malaria-causing parasites.
Heledd Davies, Hugo Belda, Malgorzata Broncel, Jill Dalimot, Moritz Treeck

Elife· September 2023

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Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in .
Alex W Chan, Malgorzata Broncel, Eden Yifrach, Nicole Haseley, Sundeep Chakladar, Moritz Treeck

bioRxiv· August 2023

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The Lactate/H Transporter PfFNT Is Essential and Druggable .
Heledd Davies, Bärbel Bergmann, Philipp Walloch, Cornelius Nerlich, Christian Hansen, Moritz Treeck

Antimicrob Agents Chemother· August 2023

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A heterotrimeric complex of Toxoplasma proteins promotes parasite survival in interferon gamma-stimulated human cells.
Eloise J Lockyer, Francesca Torelli, Simon Butterworth, Ok-Ryul Song, Steven Howell, Moritz Treeck

PLoS Biol· July 2023

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Toxoplasma gondii virulence factor ROP1 reduces parasite susceptibility to murine and human innate immune restriction.
Simon Butterworth, Francesca Torelli, Eloise J Lockyer, Jeanette Wagener, Ok-Ryul Song, Moritz Treeck

PLoS Pathog· December 2022

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A positive feedback loop mediates crosstalk between calcium, cyclic nucleotide and lipid signalling in calcium-induced Toxoplasma gondii egress.
Stephanie D Nofal, Caia Dominicus, Malgorzata Broncel, Nicholas J Katris, Helen R Flynn, Moritz Treeck

PLoS Pathog· October 2022

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Gliding motility of merozoites.
Kazuhide Yahata, Melissa N Hart, Heledd Davies, Masahito Asada, Samuel C Wassmer, Moritz Treeck

Proc Natl Acad Sci U S A· November 2021

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A 39-Amino-Acid C-Terminal Truncation of GDV1 Disrupts Sexual Commitment in Plasmodium falciparum.
Marta Tibúrcio, Eva Hitz, Igor Niederwieser, Gavin Kelly, Heledd Davies, Moritz Treeck

mSphere· May 2021

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Label-Based Mass Spectrometry Approaches for Robust Quantification of the Phosphoproteome and Total Proteome in Toxoplasma gondii.
Malgorzata Broncel, Moritz Treeck

Methods Mol Biol· January 2021

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Phosphorylation of Secreted Proteins during Acute and Chronic Stages of Infection.
Joanna C Young, Malgorzata Broncel, Helena Teague, Matt R G Russell, Olivia L McGovern, Moritz Treeck

mSphere· September 2020

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Profiling of myristoylation in reveals an -myristoylated protein important for host cell penetration.
Malgorzata Broncel, Caia Dominicus, Luis Vigetti, Stephanie D Nofal, Edward J Bartlett, Moritz Treeck

Elife· July 2020

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An exported kinase family mediates species-specific erythrocyte remodelling and virulence in human malaria.
Heledd Davies, Hugo Belda, Malgorzata Broncel, Xingda Ye, Claudine Bisson, Moritz Treeck

Nat Microbiol· June 2020

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Differential requirements for cyclase-associated protein (CAP) in actin-dependent processes of .
Alex Hunt, Matthew Robert Geoffrey Russell, Jeanette Wagener, Robyn Kent, Romain Carmeille, Moritz Treeck

Elife· October 2019

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