Publications by authors named "Isabelle Paquin"

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SAR and biological evaluation of analogues of a small molecule histone deacetylase inhibitor N-(2-aminophenyl)-4-((4-(pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamide (MGCD0103).
Stéphane Raeppel, Nancy Zhou, Frédéric Gaudette, Silvana Leit, Isabelle Paquin

Bioorg Med Chem Lett· February 2009

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Discovery of N-(2-aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide (MGCD0103), an orally active histone deacetylase inhibitor.
Nancy Zhou, Oscar Moradei, Stephane Raeppel, Silvana Leit, Sylvie Frechette, Isabelle Paquin

J Med Chem· July 2008

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Design and synthesis of 4-[(s-triazin-2-ylamino)methyl]-N-(2-aminophenyl)-benzamides and their analogues as a novel class of histone deacetylase inhibitors.
Isabelle Paquin, Stéphane Raeppel, Silvana Leit, Frédéric Gaudette, Nancy Zhou

Bioorg Med Chem Lett· February 2008

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4-(Heteroarylaminomethyl)-N-(2-aminophenyl)-benzamides and their analogs as a novel class of histone deacetylase inhibitors.
Sylvie Fréchette, Silvana Leit, Soon Hyung Woo, Guillaume Lapointe, Guillaume Jeannotte, Isabelle Paquin

Bioorg Med Chem Lett· February 2008

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N-(2-Amino-phenyl)-4-(heteroarylmethyl)-benzamides as new histone deacetylase inhibitors.
Arkadii Vaisburg, Isabelle Paquin, Naomy Bernstein, Sylvie Frechette, Frederic Gaudette

Bioorg Med Chem Lett· December 2007

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Novel aminophenyl benzamide-type histone deacetylase inhibitors with enhanced potency and selectivity.
Oscar M Moradei, Tammy C Mallais, Sylvie Frechette, Isabelle Paquin, Pierre E Tessier

J Med Chem· November 2007

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Substituted N-(2-aminophenyl)-benzamides, (E)-N-(2-aminophenyl)-acrylamides and their analogues: novel classes of histone deacetylase inhibitors.
Oscar Moradei, Silvana Leit, Nancy Zhou, Sylvie Fréchette, Isabelle Paquin

Bioorg Med Chem Lett· August 2006

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Histone deacetylase inhibitors: latest developments, trends and prospects.
Oscar Moradei, Christiane R Maroun, Isabelle Paquin, Arkadii Vaisburg

Curr Med Chem Anticancer Agents· September 2005

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