Publications by authors named "Isabelle R Taylor"

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PqsE adapts the activity of the quorum-sensing transcription factor RhlR to both autoinducer concentration and promoter sequence identity.
Bilalay V Tchadi, Jesse J Derringer, Anna K Detweiler, Isabelle R Taylor

J Bacteriol· May 2025

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Protein Interaction Networks of Catalytically Active and Catalytically Inactive PqsE in Pseudomonas aeruginosa.
Isabelle R Taylor, Laura A Murray-Nerger, Todd M Greco, Dawei Liu, Ileana M Cristea

mBio· October 2022

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The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against .
Isabelle R Taylor, Philip D Jeffrey, Dina A Moustafa, Joanna B Goldberg, Bonnie L Bassler

Biochemistry· September 2022

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Selective vulnerabilities in the proteostasis network of castration-resistant prostate cancer.
Arielle Shkedi, Isabelle R Taylor, Frank Echtenkamp, Poornima Ramkumar, Mohamed Alshalalfa

Cell Chem Biol· March 2022

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The PqsE-RhlR Interaction Regulates RhlR DNA Binding to Control Virulence Factor Production in .
Kayla A Simanek, Isabelle R Taylor, Erica K Richael, Erica Lasek-Nesselquist, Bonnie L Bassler

Microbiol Spectr· February 2022

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Inhibitor Mimetic Mutations in the PqsE Enzyme Reveal a Protein-Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production.
Isabelle R Taylor, Jon E Paczkowski, Philip D Jeffrey, Brad R Henke, Chari D Smith

ACS Chem Biol· April 2021

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Functional genomics screen identifies proteostasis targets that modulate prion protein (PrP) stability.
Jennifer Abrams, Taylor Arhar, Sue Ann Mok, Isabelle R Taylor, Martin Kampmann

Cell Stress Chaperones· March 2021

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Discovery of PqsE Thioesterase Inhibitors for Using DNA-Encoded Small Molecule Library Screening.
Julie S Valastyan, Michael R Tota, Isabelle R Taylor, Vasiliki Stergioula, Graham A B Hone

ACS Chem Biol· February 2020

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Tryptophan scanning mutagenesis as a way to mimic the compound-bound state and probe the selectivity of allosteric inhibitors in cells.
Isabelle R Taylor, Victoria A Assimon, Szu Yu Kuo, Silvia Rinaldi, Xiaokai Li

Chem Sci· January 2020

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A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis.
Steven M Moss, Isabelle R Taylor, Davide Ruggero, Jason E Gestwicki, Kevan M Shokat

Cell Host Microbe· March 2019

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A Local Allosteric Network in Heat Shock Protein 70 (Hsp70) Links Inhibitor Binding to Enzyme Activity and Distal Protein-Protein Interactions.
Silvia Rinaldi, Victoria A Assimon, Zapporah T Young, Giulia Morra, Hao Shao, Isabelle R Taylor

ACS Chem Biol· November 2018

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The disorderly conduct of Hsc70 and its interaction with the Alzheimer's-related Tau protein.
Isabelle R Taylor, Atta Ahmad, Taia Wu, Bryce A Nordhues, Anup Bhullar

J Biol Chem· July 2018

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High-throughput screen for inhibitors of protein-protein interactions in a reconstituted heat shock protein 70 (Hsp70) complex.
Isabelle R Taylor, Bryan M Dunyak, Tomoko Komiyama, Hao Shao, Xu Ran

J Biol Chem· March 2018

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Targeting Allosteric Control Mechanisms in Heat Shock Protein 70 (Hsp70).
Xiaokai Li, Hao Shao, Isabelle R Taylor, Jason E Gestwicki

Curr Top Med Chem· February 2017

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RNA binding and inhibition of primer extension by a Ru(III)/Pt(II) metal complex.
Swapan S Jain, Craig M Anderson, Francesca DiRienzo, Isabelle R Taylor, Kyan Jain

Chem Commun (Camb)· June 2013

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Hetero-multinuclear ruthenium(III)/platinum(II) complexes that potentially exhibit both antimetastatic and antineoplastic properties.
Craig M Anderson, Isabelle R Taylor, Michael F Tibbetts, Jessica Philpott, Yongfeng Hu

Inorg Chem· December 2012

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