Publications by authors named "Victoria A Assimon"

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Genetic Inhibition of APOL1 Pore-Forming Function Prevents APOL1-Mediated Kidney Disease.
Adriana M Hung, Victoria A Assimon, Hua-Chang Chen, Zhihong Yu, Caitlyn Vlasschaert

J Am Soc Nephrol· November 2023

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Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys.
Mihalis S Kariolis, Robert C Wells, Jennifer A Getz, Wanda Kwan, Cathal S Mahon, Victoria A Assimon

Sci Transl Med· May 2020

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Tryptophan scanning mutagenesis as a way to mimic the compound-bound state and probe the selectivity of allosteric inhibitors in cells.
Isabelle R Taylor, Victoria A Assimon, Szu Yu Kuo, Silvia Rinaldi, Xiaokai Li

Chem Sci· January 2020

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Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases.
Matthew Ravalin, Panagiotis Theofilas, Koli Basu, Kwadwo A Opoku-Nsiah, Victoria A Assimon

Nat Chem Biol· August 2019

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CB-6644 Is a Selective Inhibitor of the RUVBL1/2 Complex with Anticancer Activity.
Victoria A Assimon, Yangzhong Tang, Jesse D Vargas, Grace J Lee, Zhi Yong Wu

ACS Chem Biol· February 2019

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Predicting protein targets for drug-like compounds using transcriptomics.
Nicolas A Pabon, Yan Xia, Samuel K Estabrooks, Zhaofeng Ye, Amanda K Herbrand, Victoria A Assimon

PLoS Comput Biol· December 2018

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A Local Allosteric Network in Heat Shock Protein 70 (Hsp70) Links Inhibitor Binding to Enzyme Activity and Distal Protein-Protein Interactions.
Silvia Rinaldi, Victoria A Assimon, Zapporah T Young, Giulia Morra, Hao Shao

ACS Chem Biol· November 2018

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Mapping interactions with the chaperone network reveals factors that protect against tau aggregation.
Sue-Ann Mok, Carlo Condello, Rebecca Freilich, Anne Gillies, Taylor Arhar, Victoria A Assimon

Nat Struct Mol Biol· May 2018

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Protein cross-linking capillary electrophoresis at increased throughput for a range of protein-protein interactions.
Claire M Ouimet, Mohamed Dawod, James Grinias, Victoria A Assimon, Jean Lodge

Analyst· April 2018

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High-throughput screen for inhibitors of protein-protein interactions in a reconstituted heat shock protein 70 (Hsp70) complex.
Isabelle R Taylor, Bryan M Dunyak, Tomoko Komiyama, Hao Shao, Xu Ran, Victoria A Assimon

J Biol Chem· March 2018

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Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy.
Zapporah T Young, Jennifer N Rauch, Victoria A Assimon, Umesh K Jinwal, Misol Ahn

Cell Chem Biol· August 2016

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Specific Binding of Tetratricopeptide Repeat Proteins to Heat Shock Protein 70 (Hsp70) and Heat Shock Protein 90 (Hsp90) Is Regulated by Affinity and Phosphorylation.
Victoria A Assimon, Daniel R Southworth, Jason E Gestwicki

Biochemistry· December 2015

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The active Hsc70/tau complex can be exploited to enhance tau turnover without damaging microtubule dynamics.
Sarah N Fontaine, Mackenzie D Martin, Elias Akoury, Victoria A Assimon, Sergiy Borysov

Hum Mol Genet· July 2015

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Isoform-selective Genetic Inhibition of Constitutive Cytosolic Hsp70 Activity Promotes Client Tau Degradation Using an Altered Co-chaperone Complement.
Sarah N Fontaine, Jennifer N Rauch, Bryce A Nordhues, Victoria A Assimon, Andrew R Stothert

J Biol Chem· May 2015

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Concise Synthesis of Spergualin-Inspired Molecules With Broad-Spectrum Antibiotic Activity.
Victoria A Assimon, Hao Shao, Sylvie Garneau-Tsodikova, Jason E Gestwicki

Medchemcomm· May 2015

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A novel glucose 6-phosphate isomerase from Listeria monocytogenes.
David L Cech, Pan-Fen Wang, Melissa C Holt, Victoria A Assimon, Jeffrey M Schaub

Protein J· October 2014

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The molecular chaperone Hsp70 activates protein phosphatase 5 (PP5) by binding the tetratricopeptide repeat (TPR) domain.
Jamie N Connarn, Victoria A Assimon, Rebecca A Reed, Eric Tse, Daniel R Southworth

J Biol Chem· January 2014

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Hsp70 protein complexes as drug targets.
Victoria A Assimon, Anne T Gillies, Jennifer N Rauch, Jason E Gestwicki

Curr Pharm Des· October 2013

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The E3 ubiquitin ligase CHIP and the molecular chaperone Hsc70 form a dynamic, tethered complex.
Matthew C Smith, K Matthew Scaglione, Victoria A Assimon, Srikanth Patury, Andrea D Thompson

Biochemistry· August 2013

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