Publications by authors named "Mackenzie D Martin"

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Shannon E Hill, David Beaulieu-Abdelahad, Andrea Lemus, Jack M Webster, Santiago Rodriguez Ospina, Mackenzie D Martin

ACS Chem Biol· May 2023

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Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability.
Hailee F Scelsi, Kamisha R Hill, Brett M Barlow, Mackenzie D Martin, Raquel L Lieberman

Dis Model Mech· January 2023

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Calcium dysregulation potentiates wild-type myocilin misfolding: implications for glaucoma pathogenesis.
Emily G Saccuzzo, Mackenzie D Martin, Kamisha R Hill, Minh Thu Ma, Yemo Ku

J Biol Inorg Chem· September 2022

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Molecular architecture and modifications of full-length myocilin.
Mackenzie D Martin, Dustin J E Huard, Ricardo C Guerrero-Ferreira, Ishani M Desai, Brett M Barlow

Exp Eye Res· October 2021

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Stable calcium-free myocilin olfactomedin domain variants reveal challenges in differentiating between benign and glaucoma-causing mutations.
Shannon E Hill, Michelle S Kwon, Mackenzie D Martin, Amirthaa Suntharalingam, Anthony Hazel

J Biol Chem· August 2019

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Spermidine/spermine-N-acetyltransferase ablation impacts tauopathy-induced polyamine stress response.
Leslie A Sandusky-Beltran, Andrii Kovalenko, Chao Ma, John Ivan T Calahatian, Devon S Placides, Mackenzie D Martin

Alzheimers Res Ther· June 2019

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β Cell tone is defined by proglucagon peptides through cAMP signaling.
Megan E Capozzi, Berit Svendsen, Sara E Encisco, Sophie L Lewandowski, Mackenzie D Martin

JCI Insight· March 2019

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Skeletal muscle-specific Cre recombinase expression, controlled by the human α-skeletal actin promoter, improves glucose tolerance in mice fed a high-fat diet.
Rami Al Batran, Keshav Gopal, Mackenzie D Martin, Kim L Ho, Malak Almutairi

Diabetologia· August 2018

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Human cyclophilin 40 unravels neurotoxic amyloids.
Jeremy D Baker, Lindsey B Shelton, Dali Zheng, Filippo Favretto, Bryce A Nordhues, Mackenzie D Martin

PLoS Biol· June 2017

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Neurodegeneration and the Heat Shock Protein 70 Machinery: Implications for Therapeutic Development.
Sarah N Fontaine, Mackenzie D Martin, Chad A Dickey

Curr Top Med Chem· February 2017

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Inhibition of Both Hsp70 Activity and Tau Aggregation in Vitro Best Predicts Tau Lowering Activity of Small Molecules.
Mackenzie D Martin, Jeremy D Baker, Amirthaa Suntharalingam, Bryce A Nordhues, Lindsey B Shelton

ACS Chem Biol· July 2016

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DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins.
Sarah N Fontaine, Dali Zheng, Jonathan J Sabbagh, Mackenzie D Martin, Dale Chaput

EMBO J· July 2016

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The active Hsc70/tau complex can be exploited to enhance tau turnover without damaging microtubule dynamics.
Sarah N Fontaine, Mackenzie D Martin, Elias Akoury, Victoria A Assimon, Sergiy Borysov

Hum Mol Genet· July 2015

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Synthesis, stereochemical analysis, and derivatization of myricanol provide new probes that promote autophagic tau clearance.
Mackenzie D Martin, Laurent Calcul, Courtney Smith, Umesh K Jinwal, Sarah N Fontaine

ACS Chem Biol· April 2015

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