Publications by authors named "Isabelle Rouiller"

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Lysine acetylation modulates s-OPA1 GTPase activity and oligomerization in mitochondrial membrane remodeling.
Javaid Jabbar, Bakht Afroze, Naomi X Y Ling, Jonathan S Oakhill, Isabelle Rouiller

Protein Sci· June 2025

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In silico and in vitro characterization of the mycobacterial protein Ku to unravel its role in non-homologous end-joining DNA repair.
Joydeep Baral, Gourab Bhattacharje, Sagarika Dash, Dibyendu Samanta, Elizabeth Hinde, Isabelle Rouiller

Int J Biol Macromol· October 2024

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Analysis of the Conformational Landscape of the N-Domains of the AAA ATPase p97: Disentangling the Continuous Conformational Variability in Partially Symmetrical Complexes.
Sepideh Valimehr, Rémi Vuillemot, Mohsen Kazemi, Slavica Jonic, Isabelle Rouiller

Int J Mol Sci· March 2024

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MDTOMO method for continuous conformational variability analysis in cryo electron subtomograms based on molecular dynamics simulations.
Rémi Vuillemot, Isabelle Rouiller, Slavica Jonić

Sci Rep· June 2023

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MDSPACE: Extracting Continuous Conformational Landscapes from Cryo-EM Single Particle Datasets Using 3D-to-2D Flexible Fitting based on Molecular Dynamics Simulation.
Rémi Vuillemot, Alex Mirzaei, Mohamad Harastani, Ilyes Hamitouche, Léo Fréchin, Isabelle Rouiller

J Mol Biol· May 2023

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Molecular Mechanisms Driving and Regulating the AAA+ ATPase VCP/p97, an Important Therapeutic Target for Treating Cancer, Neurological and Infectious Diseases.
Sepideh Valimehr, Ashish Sethi, Manjari Shukla, Sudipta Bhattacharyya, Mohsen Kazemi, Isabelle Rouiller

Biomolecules· April 2023

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In silico prediction, characterization, docking studies and molecular dynamics simulation of human p97 in complex with p37 cofactor.
Abolfazl Mirzadeh, George Kobakhidze, Rémi Vuillemot, Slavica Jonic, Isabelle Rouiller

BMC Mol Cell Biol· September 2022

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The AAA+ ATPase p97 as a novel parasite and tuberculosis drug target.
George Kobakhidze, Ashish Sethi, Sepideh Valimehr, Stuart A Ralph, Isabelle Rouiller

Trends Parasitol· July 2022

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Broad and ultra-potent cross-clade neutralization of HIV-1 by a vaccine-induced CD4 binding site bovine antibody.
Behnaz Heydarchi, Danielle S Fong, Hongmei Gao, Natalia A Salazar-Quiroz, Jack M Edwards, Isabelle Rouiller

Cell Rep Med· May 2022

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NMMD: Efficient Cryo-EM Flexible Fitting Based on Simultaneous Normal Mode and Molecular Dynamics atomic displacements.
Rémi Vuillemot, Osamu Miyashita, Florence Tama, Isabelle Rouiller, Slavica Jonic

J Mol Biol· April 2022

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A "Drug Sweeping" State of the TriABC Triclosan Efflux Pump from Pseudomonas aeruginosa.
Lucien Fabre, Abigail T Ntreh, Amira Yazidi, Inga V Leus, Jon W Weeks, Isabelle Rouiller

Structure· March 2021

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Plant-derived virus-like particle vaccines drive cross-presentation of influenza A hemagglutinin peptides by human monocyte-derived macrophages.
Alexander I Makarkov, Makan Golizeh, Elizabeth Ruiz-Lancheros, Angelica A Gopal, Ian N Costas-Cancelas, Isabelle Rouiller

NPJ Vaccines· May 2019

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An Asymmetric Opening of HIV-1 Envelope Mediates Antibody-Dependent Cellular Cytotoxicity.
Nirmin Alsahafi, Nordine Bakouche, Mohsen Kazemi, Jonathan Richard, Shilei Ding, Isabelle Rouiller

Cell Host Microbe· April 2019

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The Peptidisc, a simple method for stabilizing membrane proteins in detergent-free solution.
Michael Luke Carlson, John William Young, Zhiyu Zhao, Lucien Fabre, Daniel Jun, Isabelle Rouiller

Elife· August 2018

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Morphological characterization of a plant-made virus-like particle vaccine bearing influenza virus hemagglutinins by electron microscopy.
Brianne J Lindsay, Michal M Bonar, Ian N Costas-Cancelas, Kristin Hunt, Alexander I Makarkov, Isabelle Rouiller

Vaccine· April 2018

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Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy.
Gian-Luca McLelland, Thomas Goiran, Wei Yi, Geneviève Dorval, Carol X Chen, Isabelle Rouiller

Elife· April 2018

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Molecular mechanism of DRP1 assembly studied in vitro by cryo-electron microscopy.
Kaustuv Basu, Driss Lajoie, Tristan Aumentado-Armstrong, Jin Chen, Roman I Koning, Isabelle Rouiller

PLoS One· September 2017

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Negative Stain Single-particle EM of the Maltose Transporter in Nanodiscs Reveals Asymmetric Closure of MalK and Catalytic Roles of ATP, MalE, and Maltose.
Lucien Fabre, Huan Bao, James Innes, Franck Duong, Isabelle Rouiller

J Biol Chem· March 2017

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Structure of anthrax lethal toxin prepore complex suggests a pathway for efficient cell entry.
Lucien Fabre, Eugenio Santelli, Driss Mountassif, Annemarie Donoghue, Aviroop Biswas, Isabelle Rouiller

J Gen Physiol· October 2016

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Structure-Function Profile of MmpL3, the Essential Mycolic Acid Transporter from Mycobacterium tuberculosis.
Juan Manuel Belardinelli, Amira Yazidi, Liang Yang, Lucien Fabre, Wei Li, Isabelle Rouiller

ACS Infect Dis· October 2016

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Molecular assembly of lethal factor enzyme and pre-pore heptameric protective antigen in early stage of translocation.
Laleh Alisaraie, Isabelle Rouiller

J Mol Model· January 2016

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Cryo-EM of the pathogenic VCP variant R155P reveals long-range conformational changes in the D2 ATPase ring.
Driss Mountassif, Lucien Fabre, Younes Zaid, Dalia Halawani, Isabelle Rouiller

Biochem Biophys Res Commun· December 2015

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Quaternary structure of WzzB and WzzE polysaccharide copolymerases.
Sergei Kalynych, Maia Cherney, Mihnea Bostina, Isabelle Rouiller, Miroslaw Cygler

Protein Sci· January 2015

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Fibril formation pH controls intrafibrillar collagen biomineralization in vitro and in vivo.
Benedetto Marelli, Chiara E Ghezzi, Yu Ling Zhang, Isabelle Rouiller, Jake E Barralet

Biomaterials· January 2015

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Coordinated rearrangements between cytoplasmic and periplasmic domains of the membrane protein complex ExbB-ExbD of Escherichia coli.
Aleksandr Sverzhinsky, Lucien Fabre, Andrew L Cottreau, Damien M P Biot-Pelletier, Sofia Khalil, Isabelle Rouiller

Structure· May 2014

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