Publications by authors named "Stuart A Ralph"

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BioMalPar at 21 - a coming of age for malaria research and interventions.
Yaw Aniweh, Jerzy Dziekan, Matthijs M Jore, Steven Kho, Liliana Mancio-Silva, Stuart A Ralph

Trends Parasitol· September 2025

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Functional characterisation of components in two Plasmodium falciparum Cullin-RING-Ligase complexes.
Danushka Marapana, Simon A Cobbold, Michal Pasternak, Gerald J Shami, Stuart A Ralph

Sci Rep· July 2025

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Multiomic interrogation of an endomembrane disrupting antimalarial.
Sophie L Collier, Stuart A Ralph

Trends Parasitol· December 2024

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DNA N-glycosylases Ogg1 and EndoIII as components of base excision repair in Plasmodium falciparum organelles.
Anupama Tiwari, Neetu Verma, Himadri Shukla, Shivani Mishra, Kit Kennedy, Stuart A Ralph

Int J Parasitol· November 2024

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Apicoplast-derived isoprenoids are essential for biosynthesis of GPI protein anchors, and consequently for egress and invasion in Plasmodium falciparum.
Michaela S Bulloch, Long K Huynh, Kit Kennedy, Julie E Ralton, Malcolm J McConville, Stuart A Ralph

PLoS Pathog· September 2024

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Nonsense-mediated decay machinery in is inefficient and non-essential.
Emma McHugh, Michaela S Bulloch, Steven Batinovic, Cameron J Patrick, Drishti K Sarna, Stuart A Ralph

mSphere· August 2023

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Conservation, abundance, glycosylation profile, and localization of the TSP protein family in Cryptosporidium parvum.
Alan John, Stefanie M Bader, Niccolay Madiedo Soler, Kharizta Wiradiputri, Swapnil Tichkule, Stuart A Ralph

J Biol Chem· March 2023

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The AAA+ ATPase p97 as a novel parasite and tuberculosis drug target.
George Kobakhidze, Ashish Sethi, Sepideh Valimehr, Stuart A Ralph, Isabelle Rouiller

Trends Parasitol· July 2022

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3, 2, 1, go! Cryptosporidium counts down to sex.
Aaron R Jex, Christopher J Tonkin, Stuart A Ralph

PLoS Biol· May 2022

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Is the AT-rich DNA of malaria parasites a drug target?
Michaela S Bulloch, Stuart A Ralph

Trends Pharmacol Sci· April 2022

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Chromosome-level genome of Schistosoma haematobium underpins genome-wide explorations of molecular variation.
Andreas J Stroehlein, Pasi K Korhonen, V Vern Lee, Stuart A Ralph, Margaret Mentink-Kane

PLoS Pathog· February 2022

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The Novel bis-1,2,4-Triazine MIPS-0004373 Demonstrates Rapid and Potent Activity against All Blood Stages of the Malaria Parasite.
Katherine M Ellis, Leonardo Lucantoni, Marina Chavchich, Matthew Abraham, Amanda De Paoli, Stuart A Ralph

Antimicrob Agents Chemother· October 2021

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Non-canonical metabolic pathways in the malaria parasite detected by isotope-tracing metabolomics.
Simon A Cobbold, Madel V Tutor, Philip Frasse, Emma McHugh, Markus Karnthaler, Stuart A Ralph

Mol Syst Biol· April 2021

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Functional Characterization of the mA-Dependent Translational Modulator PfYTH.2 in the Human Malaria Parasite.
Ameya Sinha, Sebastian Baumgarten, Amy Distiller, Emma McHugh, Patty Chen, Stuart A Ralph

mBio· April 2021

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Direct Nanopore Sequencing of mRNA Reveals Landscape of Transcript Isoforms in Apicomplexan Parasites.
V Vern Lee, Louise M Judd, Aaron R Jex, Kathryn E Holt, Christopher J Tonkin, Stuart A Ralph

mSystems· March 2021

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K13, the Cytostome, and Artemisinin Resistance.
Stanley C Xie, Stuart A Ralph, Leann Tilley

Trends Parasitol· June 2020

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PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes.
Benjamin Liffner, Sonja Frölich, Gary K Heinemann, Boyin Liu, Stuart A Ralph

Nat Commun· March 2020

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Plasmodium sexual differentiation: how to make a female.
Stuart A Ralph, Alfred Cortés

Mol Microbiol· December 2019

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Decreased K13 Abundance Reduces Hemoglobin Catabolism and Proteotoxic Stress, Underpinning Artemisinin Resistance.
Tuo Yang, Lee M Yeoh, Madel V Tutor, Matthew W Dixon, Paul J McMillan, Stuart A Ralph

Cell Rep· November 2019

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Delayed Death by Plastid Inhibition in Apicomplexan Parasites.
Kit Kennedy, Emily M Crisafulli, Stuart A Ralph

Trends Parasitol· October 2019

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Alternative splicing is required for stage differentiation in malaria parasites.
Lee M Yeoh, Christopher D Goodman, Vanessa Mollard, Emma McHugh, V Vern Lee, Stuart A Ralph

Genome Biol· August 2019

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Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking.
Kit Kennedy, Simon A Cobbold, Eric Hanssen, Jakob Birnbaum, Natalie J Spillman, Stuart A Ralph

PLoS Biol· July 2019

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3,3'-Disubstituted 5,5'-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial Activity.
Lian Xue, Da-Hua Shi, Jitendra R Harjani, Fei Huang, Julia G Beveridge, Stuart A Ralph

J Med Chem· March 2019

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Alternative Splicing in Apicomplexan Parasites.
Lee M Yeoh, V Vern Lee, Geoffrey I McFadden, Stuart A Ralph

mBio· February 2019

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Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome.
Jessica L Bridgford, Stanley C Xie, Simon A Cobbold, Charisse Flerida A Pasaje, Susann Herrmann, Stuart A Ralph

Nat Commun· September 2018

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