Publications by authors named "Isabelle Ruel"

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Imputation of untreated LDL-C in treated subjects with homozygous familial hypercholesterolaemia: An international collaboration.
G B John Mancini, Arnold Ryomoto, Isabelle Ruel, Iulia Iatan, Frederick J Raal

Atherosclerosis· January 2026

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Polygenic risk score for coronary artery disease predicts atherosclerotic cardiovascular disease in familial hypercholesterolemia.
Martine Paquette, Mark Trinder, Isabelle Ruel, Simon-Pierre Guay, Robert A Hegele

J Clin Lipidol· June 2025

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Extreme LDL-C concentration is associated with increased cardiovascular disease in women with homozygous familial hypercholesterolemia.
Martine Paquette, Isabelle Ruel, Simon-Pierre Guay, Zobaida Al-Baldawi, Diane Brisson

J Clin Lipidol· April 2025

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Low-Dose Docetaxel Is Effective in Reducing Atherogenic Lipids and Atherosclerosis.
Hong Y Choi, Isabelle Ruel, Shiwon Choi, Iulia Iatan, Senna Choi

Int J Mol Sci· February 2025

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Sex differences in treatment of familial hypercholesterolaemia: a meta-analysis.
Iulia Iatan, Leo E Akioyamen, Isabelle Ruel, Amanda Guerin, Lindsay Hales

Eur Heart J· September 2024

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Influence of Polygenic Background on the Clinical Presentation of Familial Hypercholesterolemia.
Mark Trinder, Lubomira Cermakova, Isabelle Ruel, Alexis Baass, Martine Paquette

Arterioscler Thromb Vasc Biol· July 2024

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Sex differences in the presentation, treatment and outcomes of patients with homozygous familial hypercholesterolemia.
Zobaida Al-Baldawi, Leslie Brown, Isabelle Ruel, Alexis Baass, Jean Bergeron

J Clin Lipidol· May 2024

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Sex differences in the perception of cardiovascular risk in familial hypercholesterolemia.
Balaqis Alshibani, Iulia Iatan, Amanda Guerin, Isabelle Ruel, Lubomira Cermakova

J Clin Lipidol· March 2024

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Genetic testing for familial hypercholesterolemia in Quebec, Canada: a single-centre retrospective cohort study.
Amanda Guerin, Iulia Iatan, Isabelle Ruel, Linda Fri Ngufor, Jacques Genest

CMAJ Open· August 2023

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Docetaxel as a Model Compound to Promote HDL (High-Density Lipoprotein) Biogenesis and Reduce Atherosclerosis.
Hong Y Choi, Iulia Iatan, Isabelle Ruel, Leslie Brown, Lindsay Hales

Arterioscler Thromb Vasc Biol· May 2023

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Homozygous Familial Hypercholesterolemia in Canada: An Observational Study.
Leslie Brown, Isabelle Ruel, Alexis Baass, Jean Bergeron, Liam R Brunham

JACC Adv· May 2023

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Biomedical Advances in ABCA1 Transporter: From Bench to Bedside.
Hong Y Choi, Senna Choi, Iulia Iatan, Isabelle Ruel, Jacques Genest

Biomedicines· February 2023

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Aortic stenosis in homozygous familial hypercholesterolaemia: a paradigm shift over a century.
Alexandre M Bélanger, Leo E Akioyamen, Isabelle Ruel, Lindsay Hales, Jacques Genest

Eur Heart J· September 2022

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Major adverse cardiovascular events in homozygous familial hypercholesterolaemia: a systematic review and meta-analysis.
Adam I Kramer, Leo E Akioyamen, Seohyuk Lee, Alexandre Bélanger, Isabelle Ruel

Eur J Prev Cardiol· May 2022

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Health-related quality of life in homozygous familial hypercholesterolemia: A systematic review and meta-analysis.
Latifah Alothman, Alexandre M Bélanger, Isabelle Ruel, Liam R Brunham, Lindsay Hales

J Clin Lipidol· April 2022

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Influence of the LDL-Receptor Genotype on Statin Response in Heterozygous Familial Hypercholesterolemia: Insights From the Canadian FH Registry.
Gabrielle Roy, Patrick Couture, Jacques Genest, Isabelle Ruel, Alexis Baass

Can J Cardiol· March 2022

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New Strategies to Promote Macrophage Cholesterol Efflux.
Hong Y Choi, Isabelle Ruel, Shiwon Choi, Jacques Genest

Front Cardiovasc Med· December 2021

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Sex Differences in the Presentation, Treatment, and Outcome of Patients With Familial Hypercholesterolemia.
Natalia Ryzhaya, Lubomira Cermakova, Mark Trinder, Isabelle Ruel, Thais Coutinho

J Am Heart Assoc· June 2021

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Identification of Docetaxel as a Potential Drug to Promote HDL Biogenesis.
Hong Y Choi, Isabelle Ruel, Jacques Genest

Front Pharmacol· May 2021

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Dj1 deficiency protects against atherosclerosis with anti-inflammatory response in macrophages.
Tharini Sivasubramaniyam, Jiaqi Yang, Henry S Cheng, Alexandra Zyla, Angela Li, Isabelle Ruel

Sci Rep· February 2021

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Lomitapide for treatment of homozygous familial hypercholesterolemia: The Québec experience.
Sumayah Aljenedil, Latifah Alothman, Alexandre M Bélanger, Leslie Brown, Zubin Lahijanian, Isabelle Ruel

Atherosclerosis· October 2020

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The Lifelong Burden of Homozygous Familial Hypercholesterolemia.
Ambuja Banerjee, Latifah Alothman, Patrick Couture, Jean Bergeron, Alexandre M Bélanger, Isabelle Ruel

Can J Cardiol· October 2019

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Genetic testing for familial hypercholesterolemia: Impact on diagnosis, treatment and cardiovascular risk.
Seohyuk Lee, Leo E Akioyamen, Sumayah Aljenedil, Jean-Baptiste Rivière, Isabelle Ruel

Eur J Prev Cardiol· August 2019

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Prediction of Familial Hypercholesterolemia in Patients at High Atherosclerotic Cardiovascular Disease Risk Using a Recently Validated Algorithm.
Latifah Alothman, Magdaline Zawadka, Sumayah Aljenedil, Mahesh Kajil, David Bewick, Isabelle Ruel

CJC Open· July 2019

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Canadian Cardiovascular Society Position Statement on Familial Hypercholesterolemia: Update 2018.
Liam R Brunham, Isabelle Ruel, Sumayah Aljenedil, Jean-Baptiste Rivière, Alexis Baass

Can J Cardiol· December 2018

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