Publications by authors named "Issay Kitabayashi"

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CTCF Is Essential for the Development and Maintenance of CALM-AF10-Induced Leukemia.
Yoko Kuroki, Kazutsune Yamagata, Yukiko Aikawa, Yutaka Shima, Hisafumi Shioneri, Issay Kitabayashi

Cancer Sci· November 2025

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Regulation of H3K4me3 breadth and MYC expression by the SETD1B catalytic domain in MLL-rearranged leukemia.
Shintaro Izumi, Ko Ohtani, Makoto Matsumoto, Seito Shibata, Bahityar Rahmutulla, Issay Kitabayashi

Leukemia· July 2025

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Color differences of intraprocedural bleeding between white light and red dichromatic imaging during endoscopic submucosal dissection: a post hoc analysis of a multicenter, open-label, randomized controlled trial (with videos).
Mai Makiguchi, Seiichiro Abe, Ai Fujimoto, Ryosuke Kawagoe, Takeshi Uozumi, Issay Kitabayashi

Surg Endosc· July 2025

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Loss of NOL10 leads to impaired disease progression of NUP98::DDX10 leukemia.
Yutaka Shima, Kazutsune Yamagata, Yoko Kuroki, Kazuki Sasaki, Yukiko Aikawa, Issay Kitabayashi

Leukemia· June 2025

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Genetic and chemical targeting of the ATPase complex TIP48 and 49 impairs acute myeloid leukemia.
Ayuna Hattori, Emi Takamatsu-Ichihara, Yoshiki Yamamoto, Shuhei Fujita, Kazutsune Yamagata, Issay Kitabayashi

Leukemia· September 2023

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Dual inhibition of EZH1/2 induces cell cycle arrest of B cell acute lymphoblastic leukemia cells through upregulation of CDKN1C and TP53INP1.
Jumpei Ito, Kazutsune Yamagata, Haruka Shinohara, Yutaka Shima, Takuo Katsumoto, Issay Kitabayashi

Int J Hematol· January 2023

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Dual targeting of EZH1 and EZH2 for the treatment of malignant rhabdoid tumors.
Haruka Shinohara, Rie Sawado, Makoto Nakagawa, Ayuna Hattori, Kazutsune Yamagata, Issay Kitabayashi

Mol Ther Oncolytics· December 2022

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Prognostic impact of IDH mutations in chondrosarcoma.
Makoto Nakagawa, Masaya Sekimizu, Makoto Endo, Eisuke Kobayashi, Shintaro Iwata, Issay Kitabayashi

J Orthop Sci· November 2022

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MOZ is critical for the development of MOZ/MLL fusion-induced leukemia through regulation of Hoxa9/Meis1 expression.
Takuo Katsumoto, Yoko Ogawara, Kazutsune Yamagata, Yukiko Aikawa, Ryo Goitsuka, Issay Kitabayashi

Blood Adv· October 2022

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Clinical usefulness of 2-hydroxyglutarate as a biomarker in IDH-mutant chondrosarcoma.
Makoto Nakagawa, Masayuki Yamaguchi, Makoto Endo, Yukino Machida, Ayuna Hattori, Issay Kitabayashi

J Bone Oncol· June 2022

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Tip60 activates Hoxa9 and Meis1 expression through acetylation of H2A.Z, promoting MLL-AF10 and MLL-ENL acute myeloid leukemia.
Kazutsune Yamagata, Mika Shino, Yukiko Aikawa, Shuhei Fujita, Issay Kitabayashi

Leukemia· October 2021

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The membrane-linked adaptor FRS2β fashions a cytokine-rich inflammatory microenvironment that promotes breast cancer carcinogenesis.
Yasuto Takeuchi, Natsuko Kimura, Takahiko Murayama, Yukino Machida, Daisuke Iejima, Issay Kitabayashi

Proc Natl Acad Sci U S A· October 2021

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Ppp6c deficiency accelerates K-ras -induced tongue carcinogenesis.
Kazuhiro Kishimoto, Kosuke Kanazawa, Miyuki Nomura, Takuji Tanaka, Taeko Shigemoto-Kuroda, Issay Kitabayashi

Cancer Med· July 2021

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CDKN1C-mediated growth inhibition by an EZH1/2 dual inhibitor overcomes resistance of mantle cell lymphoma to ibrutinib.
Yuki Kagiyama, Shuhei Fujita, Yutaka Shima, Kazutsune Yamagata, Takuo Katsumoto, Issay Kitabayashi

Cancer Sci· June 2021

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Autophagy regulates levels of tumor suppressor enzyme protein phosphatase 6.
Nobuyuki Fujiwara, Shusaku Shibutani, Yusuke Sakai, Toshio Watanabe, Issay Kitabayashi

Cancer Sci· December 2020

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Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia.
Ryo Miyamoto, Hiroshi Okuda, Akinori Kanai, Satoshi Takahashi, Takeshi Kawamura, Issay Kitabayashi

Cell Rep· September 2020

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A Potent Blood-Brain Barrier-Permeable Mutant IDH1 Inhibitor Suppresses the Growth of Glioblastoma with IDH1 Mutation in a Patient-Derived Orthotopic Xenograft Model.
Yukino Machida, Makoto Nakagawa, Hironori Matsunaga, Masayuki Yamaguchi, Yoko Ogawara, Issay Kitabayashi

Mol Cancer Ther· February 2020

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Selective inhibition of mutant IDH1 by DS-1001b ameliorates aberrant histone modifications and impairs tumor activity in chondrosarcoma.
Makoto Nakagawa, Fumihiko Nakatani, Hironori Matsunaga, Takahiko Seki, Makoto Endo, Issay Kitabayashi

Oncogene· October 2019

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NUP98-HBO1-fusion generates phenotypically and genetically relevant chronic myelomonocytic leukemia pathogenesis.
Yoshihiro Hayashi, Yuka Harada, Yuki Kagiyama, Sayuri Nishikawa, Ye Ding, Issay Kitabayashi

Blood Adv· April 2019

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Dual inhibition of enhancer of zeste homolog 1/2 overactivates WNT signaling to deplete cancer stem cells in multiple myeloma.
Makoto Nakagawa, Shuhei Fujita, Takuo Katsumoto, Kazutsune Yamagata, Yoko Ogawara, Issay Kitabayashi

Cancer Sci· January 2019

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Development of a simple new flow cytometric antibody-dependent cellular cytotoxicity (ADCC) assay with excellent sensitivity.
Miho Tanaka, Akiko Ishige, Masami Yaguchi, Takehisa Matsumoto, Mikako Shirouzu, Issay Kitabayashi

J Immunol Methods· January 2019

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Deep spontaneous molecular remission in a patient with congenital acute myeloid leukemia expressing a novel MOZ-p300 fusion transcript.
Yasuhiro Ikawa, Ryosei Nishimura, Hideaki Maeba, Toshihiro Fujiki, Rie Kuroda, Issay Kitabayashi

Leuk Lymphoma· October 2018

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Oncogenic roles of enhancer of zeste homolog 1/2 in hematological malignancies.
Makoto Nakagawa, Issay Kitabayashi

Cancer Sci· August 2018

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Ring1A and Ring1B inhibit expression of Glis2 to maintain murine AML stem cells.
Haruko Shima, Emi Takamatsu-Ichihara, Mika Shino, Kazutsune Yamagata, Takuo Katsumoto, Issay Kitabayashi

Blood· April 2018

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Mllt10 knockout mouse model reveals critical role of Af10-dependent H3K79 methylation in midfacial development.
Honami Ogoh, Kazutsune Yamagata, Tomomi Nakao, Lisa L Sandell, Ayaka Yamamoto, Issay Kitabayashi

Sci Rep· September 2017

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