Publications by authors named "Itamar Simon"

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Improved spike-in normalization clarifies the relationship between active histone modifications and transcription.
Lauren Patel, Yuwei Cao, Tianyao Xu, Eduardo Modolo, Tamar Dishon, Itamar Simon

bioRxiv· November 2025

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Unveiling Replication Timing-Dependent Mutational Biases: Mechanistic Insights from Gene Knockouts and Genotoxins Exposures.
Hadas Gross-Samuels, Amnon Koren, Itamar Simon

Int J Mol Sci· July 2025

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Harnessing DNA replication stress to target RBM10 deficiency in lung adenocarcinoma.
Feras E Machour, Enas R Abu-Zhayia, Joyce Kamar, Alma Sophia Barisaac, Itamar Simon

Nat Commun· July 2024

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Cancer mutational signatures identification in clinical assays using neural embedding-based representations.
Adar Yaacov, Gil Ben Cohen, Jakob Landau, Tom Hope, Itamar Simon

Cell Rep Med· June 2024

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Unbiased phenotype and genotype matching maximizes gene discovery and diagnostic yield.
Jonathan Rips, Orli Halstuk, Adina Fuchs, Ziv Lang, Tal Sido, Simon Edvardson, Itamar Simon

Genet Med· April 2024

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A Cyclic Permutation Approach to Removing Spatial Dependency between Clustered Gene Ontology Terms.
Rachel Rapoport, Avraham Greenberg, Zohar Yakhini, Itamar Simon

Biology (Basel)· March 2024

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Both cell autonomous and non-autonomous processes modulate the association between replication timing and mutation rate.
Oriya Vardi-Yaacov, Adar Yaacov, Shai Rosenberg, Itamar Simon

Sci Rep· August 2023

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Characterization of Unidirectional Replication Forks in the Mouse Genome.
Avital Zerbib, Itamar Simon

Int J Mol Sci· June 2023

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Mutational signatures association with replication timing in normal cells reveals similarities and differences with matched cancer tissues.
Adar Yaacov, Shai Rosenberg, Itamar Simon

Sci Rep· May 2023

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Mitotic H3K9ac is controlled by phase-specific activity of HDAC2, HDAC3, and SIRT1.
Shashi Gandhi, Raizy Mitterhoff, Rachel Rapoport, Marganit Farago, Avraham Greenberg, Itamar Simon

Life Sci Alliance· October 2022

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S Phase Duration Is Determined by Local Rate and Global Organization of Replication.
Avraham Greenberg, Itamar Simon

Biology (Basel)· May 2022

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RIF1-ASF1-mediated high-order chromatin structure safeguards genome integrity.
Sumin Feng, Sai Ma, Kejiao Li, Shengxian Gao, Shaokai Ning, Itamar Simon

Nat Commun· February 2022

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Cancer Mutational Processes Vary in Their Association with Replication Timing and Chromatin Accessibility.
Adar Yaacov, Oriya Vardi, Britny Blumenfeld, Avraham Greenberg, Dashiell J Massey, Itamar Simon

Cancer Res· December 2021

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Asynchronous Replication Timing: A Mechanism for Monoallelic Choice During Development.
Yehudit Bergman, Itamar Simon, Howard Cedar

Front Cell Dev Biol· October 2021

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Chromosomal coordination and differential structure of asynchronous replicating regions.
Britny Blumenfeld, Hagit Masika, Marganit Farago, Yishai Yehuda, Lamia Halaseh, Itamar Simon

Nat Commun· February 2021

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Study of mitotic chromatin supports a model of bookmarking by histone modifications and reveals nucleosome deposition patterns.
Elisheva Javasky, Inbal Shamir, Shashi Gandhi, Shawn Egri, Oded Sandler, Itamar Simon

Genome Res· October 2018

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Germline DNA replication timing shapes mammalian genome composition.
Yishai Yehuda, Britny Blumenfeld, Nina Mayorek, Kirill Makedonski, Oriya Vardi, Itamar Simon

Nucleic Acids Res· September 2018

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Biases in the SMART-DNA library preparation method associated with genomic poly dA/dT sequences.
Oriya Vardi, Inbal Shamir, Elisheva Javasky, Alon Goren, Itamar Simon

PLoS One· August 2017

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Perturbations in the Replication Program Contribute to Genomic Instability in Cancer.
Britny Blumenfeld, Micha Ben-Zimra, Itamar Simon

Int J Mol Sci· May 2017

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Genome-wide Determination of Mammalian Replication Timing by DNA Content Measurement.
Yishai Yehuda, Britny Blumenfeld, Dan Lehmann, Itamar Simon

J Vis Exp· January 2017

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Persistence to anti-cancer treatments in the stationary to proliferating transition.
Sivan Pearl Mizrahi, Orit Gefen, Itamar Simon, Nathalie Q Balaban

Cell Cycle· December 2016

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The mutation spectrum in genomic late replication domains shapes mammalian GC content.
Ephraim Kenigsberg, Yishai Yehuda, Lisette Marjavaara, Andrea Keszthelyi, Andrei Chabes, Itamar Simon

Nucleic Acids Res· May 2016

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Distinguishing between stochasticity and determinism: Examples from cell cycle duration variability.
Sivan Pearl Mizrahi, Oded Sandler, Laura Lande-Diner, Nathalie Q Balaban, Itamar Simon

Bioessays· January 2016

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Lineage correlations of single cell division time as a probe of cell-cycle dynamics.
Oded Sandler, Sivan Pearl Mizrahi, Noga Weiss, Oded Agam, Itamar Simon

Nature· March 2015

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The p53 C terminus controls site-specific DNA binding and promotes structural changes within the central DNA binding domain.
Oleg Laptenko, Idit Shiff, Will Freed-Pastor, Andrew Zupnick, Melissa Mattia, Itamar Simon

Mol Cell· March 2015

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