Publications by authors named "Oleg Laptenko"

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p53 Frameshift Mutations Couple Loss-of-Function with Unique Neomorphic Activities.
David R Tong, Wen Zhou, Chen Katz, Kausik Regunath, Divya Venkatesh, Oleg Laptenko

Mol Cancer Res· September 2021

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Accurate and sensitive quantification of protein-DNA binding affinity.
Chaitanya Rastogi, H Tomas Rube, Judith F Kribelbauer, Justin Crocker, Ryan E Loker, Oleg Laptenko

Proc Natl Acad Sci U S A· April 2018

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Wild-type and cancer-related p53 proteins are preferentially degraded by MDM2 as dimers rather than tetramers.
Chen Katz, Ana Maria Low-Calle, Joshua H Choe, Oleg Laptenko, David Tong

Genes Dev· March 2018

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Quantitative Analysis of the DNA Methylation Sensitivity of Transcription Factor Complexes.
Judith F Kribelbauer, Oleg Laptenko, Siying Chen, Gabriella D Martini, William A Freed-Pastor

Cell Rep· June 2017

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p53: master of life, death, and the epigenome.
Oleg Laptenko, Carol Prives

Genes Dev· May 2017

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The Tail That Wags the Dog: How the Disordered C-Terminal Domain Controls the Transcriptional Activities of the p53 Tumor-Suppressor Protein.
Oleg Laptenko, David R Tong, James Manfredi, Carol Prives

Trends Biochem Sci· December 2016

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Lysines in the tetramerization domain of p53 selectively modulate G1 arrest.
Rachel Beckerman, Kathryn Yoh, Melissa Mattia-Sansobrino, Andrew Zupnick, Oleg Laptenko

Cell Cycle· June 2016

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Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells.
Neil T Pfister, Vitalay Fomin, Kausik Regunath, Jeffrey Y Zhou, Wen Zhou, Oleg Laptenko

Genes Dev· June 2015

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The p53 C terminus controls site-specific DNA binding and promotes structural changes within the central DNA binding domain.
Oleg Laptenko, Idit Shiff, Will Freed-Pastor, Andrew Zupnick, Melissa Mattia

Mol Cell· March 2015

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MOZ increases p53 acetylation and premature senescence through its complex formation with PML.
Susumu Rokudai, Oleg Laptenko, Suzzette M Arnal, Yoichi Taya, Issay Kitabayashi

Proc Natl Acad Sci U S A· March 2013

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Anything but simple: a phosphorylation-driven toggle within Brd4 triggers gene-specific transcriptional activation.
Oleg Laptenko, Carol Prives

Mol Cell· March 2013

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The p53-HAT connection: PCAF rules?
Oleg Laptenko, Carol Prives

Cell Cycle· August 2012

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p53-Dependent induction of PVT1 and miR-1204.
Anthony M Barsotti, Rachel Beckerman, Oleg Laptenko, Konrad Huppi, Natasha J Caplen

J Biol Chem· January 2012

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DECOD: fast and accurate discriminative DNA motif finding.
Peter Huggins, Shan Zhong, Idit Shiff, Rachel Beckerman, Oleg Laptenko

Bioinformatics· September 2011

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p53 binding to nucleosomes within the p21 promoter in vivo leads to nucleosome loss and transcriptional activation.
Oleg Laptenko, Rachel Beckerman, Ella Freulich, Carol Prives

Proc Natl Acad Sci U S A· June 2011

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The C terminus of p53 binds the N-terminal domain of MDM2.
Masha V Poyurovsky, Chen Katz, Oleg Laptenko, Rachel Beckerman, Maria Lokshin

Nat Struct Mol Biol· August 2010

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Control of the respiratory metabolism of Thermus thermophilus by the nitrate respiration conjugative element NCE.
Felipe Cava, Oleg Laptenko, Sergei Borukhov, Zahra Chahlafi, Emilio Blas-Galindo

Mol Microbiol· May 2007

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pH-dependent conformational switch activates the inhibitor of transcription elongation.
Oleg Laptenko, Seung-Sup Kim, Jookyung Lee, Marina Starodubtseva, Fellipe Cava

EMBO J· May 2006

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Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation.
Steven Tuske, Stefan G Sarafianos, Xinyue Wang, Brian Hudson, Elena Sineva, Oleg Laptenko

Cell· August 2005

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Bacterial transcription elongation factors: new insights into molecular mechanism of action.
Sergei Borukhov, Jookyung Lee, Oleg Laptenko

Mol Microbiol· March 2005

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Biochemical assays of Gre factors of Thermus thermophilus.
Oleg Laptenko, Sergei Borukhov

Methods Enzymol· February 2004

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Transcript cleavage factors GreA and GreB act as transient catalytic components of RNA polymerase.
Oleg Laptenko, Jookyung Lee, Ivan Lomakin, Sergei Borukhov

EMBO J· December 2003

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Purification, crystallization and initial crystallographic analysis of RNA polymerase holoenzyme from Thermus thermophilus.
Marina N Vassylyeva, Jookyung Lee, Shun Ichi Sekine, Oleg Laptenko, Seiki Kuramitsu

Acta Crystallogr D Biol Crystallogr· September 2002

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Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 A resolution.
Dmitry G Vassylyev, Shun-ichi Sekine, Oleg Laptenko, Jookyung Lee, Marina N Vassylyeva

Nature· June 2002

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