Publications by authors named "Ivan Scandale"

Claim this Profile
P
Population pharmacokinetic-pharmacodynamic analysis of benznidazole monotherapy and combination therapy with fosravuconazole in chronic Chagas disease (BENDITA).
Frauke Assmus, Cintia Cruz, James A Watson, Nicholas J White, Ayorinde Adehin, Ivan Scandale

PLoS Negl Trop Dis· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pharmacokinetic-pharmacodynamic modeling of benznidazole and its antitrypanosomal activity in a murine model of chronic Chagas disease.
Frauke Assmus, Ayorinde Adehin, Richard M Hoglund, Amanda Fortes Francisco, Michael D Lewis, Ivan Scandale

PLoS Negl Trop Dis· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Early assessment of antibodies decline in Chagas patients following treatment using a serological multiplex immunoassay.
Ursula Saade, Jasper de Boer, Ivan Scandale, Jaime Altcheh, Hans Pottel

Nat Commun· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A guide for the generation of repositories of clinical samples for research on Chagas disease.
Nieves Martínez-Peinado, Juan Carlos Gabaldón-Figueira, Roberto Rodrigues Ferreira, María Carmen Thomas, Manuel Carlos López, Ivan Scandale

PLoS Negl Trop Dis· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Further preclinical characterization of molnupiravir against SARS-CoV-2: Antiviral activity determinants and viral genome alteration patterns.
Paul-Rémi Petit, Franck Touret, Jean-Sélim Driouich, Maxime Cochin, Léa Luciani, Ivan Scandale

Heliyon· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Bioluminescence imaging reveals enhanced SARS-CoV-2 clearance in mice with combinatorial regimens.
Irfan Ullah, Fanny Escudie, Ivan Scandale, Zoela Gilani, Gabrielle Gendron-Lepage

iScience· March 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Generation and evaluation of protease inhibitor-resistant SARS-CoV-2 strains.
Hawa Sophia Bouzidi, Jean-Sélim Driouich, Raphaëlle Klitting, Ornéllie Bernadin, Géraldine Piorkowski, Ivan Scandale

Antiviral Res· February 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Lack of antiviral activity of probenecid in vitro and in Syrian golden hamsters.
Helen J Box, Joanne Sharp, Shaun H Pennington, Edyta Kijak, Lee Tatham, Ivan Scandale

J Antimicrob Chemother· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Onchocerciasis Drug Discovery: In Vitro Evaluation of FDA-Approved Drugs against in Gambia.
Suzanne Gokool, Simon Townson, Andrew Freeman, Jadzia Siemienski-Kleyn, Jakub Zubrzycki, Ivan Scandale

Pharmaceutics· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
State-of-the-Art in the Drug Discovery Pathway for Chagas Disease: A Framework for Drug Development and Target Validation.
Juan Carlos Gabaldón-Figueira, Nieves Martinez-Peinado, Elisa Escabia, Albert Ros-Lucas, Eric Chatelain, Ivan Scandale

Res Rep Trop Med· June 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Combinatorial Regimens Augment Drug Monotherapy for SARS-CoV-2 Clearance in Mice.
Irfan Ullah, Fanny Escudie, Ivan Scandale, Zoela Gilani, Gabrielle Gendron-Lepage

bioRxiv· June 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Comparing in vivo bioluminescence imaging and the Multi-Cruzi immunoassay platform to develop improved Chagas disease diagnostic procedures and biomarkers for monitoring parasitological cure.
Amanda Fortes Francisco, Ursula Saade, Shiromani Jayawardhana, Hans Pottel, Ivan Scandale

PLoS Negl Trop Dis· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pre-clinical evaluation of antiviral activity of nitazoxanide against SARS-CoV-2.
Jean-Sélim Driouich, Maxime Cochin, Franck Touret, Paul-Rémi Petit, Magali Gilles, Ivan Scandale

EBioMedicine· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Filarial nematode phenotypic screening cascade to identify compounds with anti-parasitic activity for drug discovery optimization.
Natalie Hawryluk, Li Zhiru, Clotilde Carlow, Suzanne Gokool, Simon Townson, Ivan Scandale

Int J Parasitol Drugs Drug Resist· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of Substituted Di(pyridin-2-yl)-1,2,4-thiadiazol-5-amines as Novel Macrofilaricidal Compounds for the Treatment of Human Filarial Infections.
Natalie Hawryluk, Dale Robinson, Yixing Shen, Graham Kyne, Matthew Bedore, Ivan Scandale

J Med Chem· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19.
Frauke Assmus, Jean-Sélim Driouich, Rana Abdelnabi, Laura Vangeel, Franck Touret, Ivan Scandale

Microorganisms· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A pharmacometric approach to evaluate drugs for potential repurposing as COVID-19 therapeutics.
Thanaporn Wattanakul, Palang Chotsiri, Ivan Scandale, Richard M Hoglund, Joel Tarning

Expert Rev Clin Pharmacol· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Drug development for the treatment of onchocerciasis: Population pharmacokinetic and adverse events modeling of emodepside.
Frauke Assmus, Richard M Hoglund, Frédéric Monnot, Sabine Specht, Ivan Scandale

PLoS Negl Trop Dis· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern.
Rana Abdelnabi, Caroline S Foo, Dirk Jochmans, Laura Vangeel, Steven De Jonghe, Ivan Scandale

Nat Commun· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluation of the in vitro susceptibility of various filarial nematodes to emodepside.
Marc P Hübner, Simon Townson, Suzanne Gokool, Senyo Tagboto, Mary J Maclean, Ivan Scandale

Int J Parasitol Drugs Drug Resist· December 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Onchocerciasis drug development: from preclinical models to humans.
Adela Ngwewondo, Ivan Scandale, Sabine Specht

Parasitol Res· December 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Development of emodepside as a possible adulticidal treatment for human onchocerciasis-The fruit of a successful industrial-academic collaboration.
Jürgen Krücken, Lindy Holden-Dye, Jennifer Keiser, Roger K Prichard, Simon Townson, Ivan Scandale

PLoS Pathog· July 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Preclinical and Clinical Characteristics of the Trichuricidal Drug Oxantel Pamoate and Clinical Development Plans: A Review.
Marta S Palmeirim, Sabine Specht, Ivan Scandale, Irene Gander-Meisterernst, Monika Chabicovsky

Drugs· June 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Animal models of Chagas disease and their translational value to drug development.
Eric Chatelain, Ivan Scandale

Expert Opin Drug Discov· December 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro.
Marc P Hübner, Coralie Martin, Sabine Specht, Marianne Koschel, Bettina Dubben, Ivan Scandale

PLoS Negl Trop Dis· July 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis