Publications by authors named "JA Milligan"

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Green Oxidation of Aromatic Hydrazide Derivatives Using an Oxoammonium Salt.
Nidheesh Phadnis, Jessica A Molen, Shannon M Stephens, Shayne M Weierbach, Kyle M Lambert, John A Milligan

J Org Chem· April 2024

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3-Chloropropylbis(catecholato)silicate as a Bifunctional Reagent for the One-Pot Synthesis of Tetrahydroquinolines from -Bromosulfonamides.
Noah Brodsky, Nidheesh Phadnis, Mohamed Ibrahim, Isabel M Andino, Inés Blanc Giro, John A Milligan

J Org Chem· March 2024

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Bicyclobutanes: from curiosities to versatile reagents and covalent warheads.
Christopher B Kelly, John A Milligan, Leon J Tilley, Taylor M Sodano

Chem Sci· October 2022

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Radical-Polar Crossover Annulation: A Platform for Accessing Polycyclic Cyclopropanes.
John A Milligan, Kevin L Burns, Anthony V Le, Viktor C Polites, Zheng-Jun Wang

Adv Synth Catal· January 2020

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Alkyl Carbon-Carbon Bond Formation by Nickel/Photoredox Cross-Coupling.
John A Milligan, James P Phelan, Shorouk O Badir, Gary A Molander

Angew Chem Int Ed Engl· May 2019

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Photoredox Radical/Polar Crossover Enables Construction of Saturated Nitrogen Heterocycles.
Loïc R E Pantaine, John A Milligan, Jennifer K Matsui, Christopher B Kelly, Gary A Molander

Org Lett· April 2019

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Radical/Polar Annulation Reactions (RPARs) Enable the Modular Construction of Cyclopropanes.
John A Milligan, James P Phelan, Viktor C Polites, Christopher B Kelly, Gary A Molander

Org Lett· November 2018

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Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy.
Robert W Myers, Hong-Ping Guan, Juliann Ehrhart, Aleksandr Petrov, Srinivasa Prahalada, James A Milligan

Science· August 2017

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Discovery of N-[Bis(4-methoxyphenyl)methyl]-4-hydroxy-2-(pyridazin-3-yl)pyrimidine-5-carboxamide (MK-8617), an Orally Active Pan-Inhibitor of Hypoxia-Inducible Factor Prolyl Hydroxylase 1-3 (HIF PHD1-3) for the Treatment of Anemia.
John S Debenham, Christina Madsen-Duggan, Matthew J Clements, Thomas F Walsh, Jeffrey T Kuethe, James A Milligan

J Med Chem· December 2016

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Hydrophosphination of Bicyclo[1.1.0]butane-1-carbonitriles.
John A Milligan, Carl A Busacca, Chris H Senanayake, Peter Wipf

Org Lett· September 2016

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Click chemistry: Straining to react.
John A Milligan, Peter Wipf

Nat Chem· April 2016

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Utilizing Low-Volume Aqueous Acoustic Transfer with the Echo 525 to Enable Miniaturization of qRT-PCR Assay.
Sony Agrawal, Steven Cifelli, Richard Johnstone, David Pechter, Deborah A Barbey, James A Milligan

J Lab Autom· February 2016

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Synthesis of phosphaguanidines by hydrophosphination of carbodiimides with phosphine boranes.
Carl A Busacca, John A Milligan, Eakkaphon Rattanangkool, Cyrus Ramavarapu, Anji Chen

J Org Chem· October 2014

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1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia.
Petr Vachal, Shouwu Miao, Joan M Pierce, Deodial Guiadeen, Vincent J Colandrea, James A Milligan

J Med Chem· April 2012

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SAR studies of 3-arylpropionic acids as potent and selective agonists of sphingosine-1-phosphate receptor-1 (S1P1) with enhanced pharmacokinetic properties.
Lin Yan, Pei Huo, Jeffrey J Hale, Sander G Mills, Richard Hajdu, James A Milligan

Bioorg Med Chem Lett· February 2007

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2-Aryl(pyrrolidin-4-yl)acetic acids are potent agonists of sphingosine-1-phosphate (S1P) receptors.
Lin Yan, Richard Budhu, Pei Huo, Christopher L Lynch, Jeffrey J Hale, James A Milligan

Bioorg Med Chem Lett· July 2006

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Highly selective and potent agonists of sphingosine-1-phosphate 1 (S1P1) receptor.
Petr Vachal, Leslie M Toth, Jeffrey J Hale, Lin Yan, Sander G Mills, James A Milligan

Bioorg Med Chem Lett· July 2006

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Discovery of 3-arylpropionic acids as potent agonists of sphingosine-1-phosphate receptor-1 (S1P1) with high selectivity against all other known S1P receptor subtypes.
Lin Yan, Pei Huo, George Doherty, Lesile Toth, Jeffrey J Hale, James A Milligan

Bioorg Med Chem Lett· July 2006

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2,5-Disubstituted pyrrolidine carboxylates as potent, orally active sphingosine-1-phosphate (S1P) receptor agonists.
Vincent J Colandrea, Irene E Legiec, Pei Huo, Lin Yan, Jeffrey J Hale, James A Milligan

Bioorg Med Chem Lett· June 2006

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Discovery of potent 3,5-diphenyl-1,2,4-oxadiazole sphingosine-1-phosphate-1 (S1P1) receptor agonists with exceptional selectivity against S1P2 and S1P3.
Zhen Li, Weirong Chen, Jeffrey J Hale, Christopher L Lynch, Sander G Mills, James A Milligan

J Med Chem· October 2005

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A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists.
Jeffrey J Hale, Christopher L Lynch, William Neway, Sander G Mills, Richard Hajdu, James A Milligan

J Med Chem· December 2004

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Design and synthesis of conformationally constrained 3-(N-alkylamino)propylphosphonic acids as potent agonists of sphingosine-1-phosphate (S1P) receptors.
Lin Yan, Jeffrey J Hale, Christopher L Lynch, Richard Budhu, Amy Gentry, James A Milligan

Bioorg Med Chem Lett· October 2004

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Synthesis, stereochemical determination and biochemical characterization of the enantiomeric phosphate esters of the novel immunosuppressive agent FTY720.
Jeffrey J Hale, Lin Yan, William E Neway, Richard Hajdu, James D Bergstrom, James A Milligan

Bioorg Med Chem· September 2004

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Antimicrobial activity of viridiofungins.
J C Onishi, J A Milligan, A Basilio, J Bergstrom, J Curotto

J Antibiot (Tokyo)· April 1997

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Two-frequency control and suppression of tunneling in the driven double well.
D Farrelly, JA Milligan

Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics· April 1993

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