Publications by authors named "Jaap Kool"

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CRISPR-Cas- induced IRF3 and MAVS knockouts in a salmonid cell line disrupt PRR signaling and affect viral replication.
Yorick A van der Wal, Henriette Nordli, Allan Akandwanaho, Linn Greiner-Tollersrud, Jaap Kool

Front Immunol· August 2023

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The importance of the Atlantic salmon peritoneal cavity B cell response: Local IgM secreting cells are predominant upon Piscirickettsia salmonis infection.
Yorick A van der Wal, Shiferaw Jenberie, Henriette Nordli, Linn Greiner-Tollersrud, Jaap Kool

Dev Comp Immunol· October 2021

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Identifying regulatory mechanisms underlying tumorigenesis using locus expression signature analysis.
Eunjee Lee, Jeroen de Ridder, Jaap Kool, Lodewyk F A Wessels, Harmen J Bussemaker

Proc Natl Acad Sci U S A· April 2014

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Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors.
Christiaan Klijn, Marco J Koudijs, Jaap Kool, Jelle ten Hoeve, Mandy Boer

PLoS One· December 2013

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High-throughput semiquantitative analysis of insertional mutations in heterogeneous tumors.
Marco J Koudijs, Christiaan Klijn, Louise van der Weyden, Jaap Kool, Jelle ten Hoeve

Genome Res· December 2011

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Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach.
Jenny Mattison, Jaap Kool, Anthony G Uren, Jeroen de Ridder, Lodewyk Wessels

Cancer Res· February 2010

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Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes.
Jaap Kool, Anthony G Uren, Carla P Martins, Daoud Sie, Jeroen de Ridder

Cancer Res· January 2010

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A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites.
Anthony G Uren, Harald Mikkers, Jaap Kool, Louise van der Weyden, Anders H Lund

Nat Protoc· September 2009

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High-throughput insertional mutagenesis screens in mice to identify oncogenic networks.
Jaap Kool, Anton Berns

Nat Rev Cancer· June 2009

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Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks.
Anthony G Uren, Jaap Kool, Konstantin Matentzoglu, Jeroen de Ridder, Jenny Mattison

Cell· May 2008

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Co-occurrence analysis of insertional mutagenesis data reveals cooperating oncogenes.
Jeroen de Ridder, Jaap Kool, Anthony Uren, Jan Bot, Lodewyk Wessels

Bioinformatics· July 2007

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Detecting statistically significant common insertion sites in retroviral insertional mutagenesis screens.
Jeroen de Ridder, Anthony Uren, Jaap Kool, Marcel Reinders, Lodewyk Wessels

PLoS Comput Biol· December 2006

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DNA damage in transcribed genes induces apoptosis via the JNK pathway and the JNK-phosphatase MKP-1.
Mohamed Hamdi, Jaap Kool, Paulien Cornelissen-Steijger, Francoise Carlotti, Herman E Popeijus

Oncogene· November 2005

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Induction of ATF3 by ionizing radiation is mediated via a signaling pathway that includes ATM, Nibrin1, stress-induced MAPkinases and ATF-2.
Jaap Kool, Mohamed Hamdi, Paulien Cornelissen-Steijger, Alex J van der Eb, Carrol Terleth

Oncogene· July 2003

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