Publications by authors named "Anthony Uren"

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Epigenetic changes induced by in utero dietary challenge result in phenotypic variability in successive generations of mice.
Mathew Van de Pette, Andrew Dimond, António M Galvão, Steven J Millership, Wilson To, Anthony G Uren

Nat Commun· May 2022

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Forward and Reverse Genetics of B Cell Malignancies: From Insertional Mutagenesis to CRISPR-Cas.
Joanna C Dawes, Anthony G Uren

Front Immunol· October 2021

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Galactose-modified duocarmycin prodrugs as senolytics.
Ana Guerrero, Romain Guiho, Nicolás Herranz, Anthony Uren, Dominic J Withers

Aging Cell· April 2020

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LUMI-PCR: an Illumina platform ligation-mediated PCR protocol for integration site cloning, provides molecular quantitation of integration sites.
Joanna C Dawes, Philip Webster, Barbara Iadarola, Claudia Garcia-Diaz, Marian Dore, Laurence Game, Anthony G Uren

Mob DNA· February 2020

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Cardiac glycosides are broad-spectrum senolytics.
Ana Guerrero, Nicolás Herranz, Bin Sun, Verena Wagner, Suchira Gallage, Anthony G Uren

Nat Metab· November 2019

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Author Correction: Subclonal mutation selection in mouse lymphomagenesis identifies known cancer loci and suggests novel candidates.
Philip Webster, Joanna C Dawes, Hamlata Dewchand, Katalin Takacs, Barbara Iadarola, Laurence Game, Anthony G Uren

Nat Commun· March 2019

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Subclonal mutation selection in mouse lymphomagenesis identifies known cancer loci and suggests novel candidates.
Philip Webster, Joanna C Dawes, Hamlata Dewchand, Katalin Takacs, Barbara Iadarola, Laurence Game, Anthony G Uren

Nat Commun· July 2018

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Visualizing Changes in Cdkn1c Expression Links Early-Life Adversity to Imprint Mis-regulation in Adults.
Mathew Van de Pette, Allifia Abbas, Amelie Feytout, Gráinne McNamara, Ludovica Bruno, Anthony Uren

Cell Rep· January 2017

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Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells.
Edward Curry, Ian Green, Nadine Chapman-Rothe, Elham Shamsaei, Sarah Kandil, Anthony G Uren

Clin Epigenetics· August 2015

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GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors.
Bart A Westerman, Marleen Blom, Ellen Tanger, Martin van der Valk, Ji-Ying Song, Anthony Uren

PLoS One· September 2012

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Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis.
H Nikki March, Alistair G Rust, Nicholas A Wright, Jelle ten Hoeve, Jeroen de Ridder, Anthony Uren

Nat Genet· November 2011

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Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice.
George S Vassiliou, Jonathan L Cooper, Roland Rad, Juan Li, Stephen Rice, Anthony Uren

Nat Genet· May 2011

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Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach.
Jenny Mattison, Jaap Kool, Anthony G Uren, Jeroen de Ridder, Lodewyk Wessels

Cancer Res· February 2010

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Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes.
Jaap Kool, Anthony G Uren, Carla P Martins, Daoud Sie, Jeroen de Ridder

Cancer Res· January 2010

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A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites.
Anthony G Uren, Harald Mikkers, Jaap Kool, Louise van der Weyden, Anders H Lund

Nat Protoc· September 2009

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Jump-starting cancer gene discovery.
Anthony Uren, Anton Berns

Nat Biotechnol· March 2009

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Instant conditional transgenesis in the mouse hematopoietic compartment.
Tamás Csikós, Rogier M Reijmers, Anthony G Uren, Marcel Spaargaren, Steven T Pals

J Immunol Methods· December 2008

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Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks.
Anthony G Uren, Jaap Kool, Konstantin Matentzoglu, Jeroen de Ridder, Jenny Mattison

Cell· May 2008

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Co-occurrence analysis of insertional mutagenesis data reveals cooperating oncogenes.
Jeroen de Ridder, Jaap Kool, Anthony Uren, Jan Bot, Lodewyk Wessels

Bioinformatics· July 2007

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Detecting statistically significant common insertion sites in retroviral insertional mutagenesis screens.
Jeroen de Ridder, Anthony Uren, Jaap Kool, Marcel Reinders, Lodewyk Wessels

PLoS Comput Biol· December 2006

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