Publications by authors named "Jack Chan"

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Evaluating the impact of relative dose intensity on efficacy of trastuzumab deruxtecan for metastatic breast cancer in the real-world clinical setting.
Han Yi Lee, Vivianne Shih, Jack Junjie Chan, Shun Zi Liong, Ryan Shea Ying Cong Tan

Ann Acad Med Singap· August 2025

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Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors.
Kevin Sek, Amanda X Y Chen, Thomas Cole, Jesse D Armitage, Junming Tong, Cheok Weng Chan, Jack D Chan

Nat Commun· July 2025

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Second-line antibody-drug conjugates for the treatment of metastatic human papillomavirus-independent gastric-type adenocarcinoma of cervix: The Singapore experience.
Daniel Jia Ming Ang, Ke Xin Bok, Shing Lih Wong, Yihan Li, Adele Wong, Jack Junjie Chan

Gynecol Oncol Rep· April 2025

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Oncofertility care and fertility preservation in gynaecological cancer: experience from Singapore's largest tertiary centre.
Qiu Ju Ng, Tat Xin Ee, Charissa Shu Ying Goh, Shi Hui Lee, Jasmine Earn Huay Low, Jack Junjie Chan

Singapore Med J· April 2025

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FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy.
Jack D Chan, Christina M Scheffler, Isabelle Munoz, Kevin Sek, Joel N Lee, Cheok Weng Chan

Nature· May 2024

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The cardioprotective potential of sodium-glucose cotransporter 2-inhibitors in breast cancer therapy-related cardiac dysfunction - A systematic review.
Jun Hua Chong, Wei-Ting Chang, Jack Junjie Chan, Tira Jing Ying Tan, Johan Wai Kay Chan

Curr Probl Cardiol· March 2024

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Evolving standards and future directions for systemic therapies in cervical cancer.
Daniel Jia Ming Ang, Jack Junjie Chan

J Gynecol Oncol· March 2024

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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
Imran G House, Emily B Derrick, Kevin Sek, Amanda X Y Chen, Jasmine Li, Cheok Weng Chan, Jack D Chan

Cell Rep· February 2024

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Emerging systemic therapy options beyond CDK4/6 inhibitors for hormone receptor-positive HER2-negative advanced breast cancer.
Jun Ma, Jack Junjie Chan, Ching Han Toh, Yoon-Sim Yap

NPJ Breast Cancer· September 2023

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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
Imran G House, Emily B Derrick, Kevin Sek, Amanda X Y Chen, Jasmine Li, Cheok Weng Chan, Jack D Chan

Cell Rep· August 2023

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Development and pilot testing of a decision aid for navigating breast cancer survivorship care.
Yu Ke, Ivy Cheng, Gretchen Ser Hua Tan, Rose Wai Yee Fok, Jack Junjie Chan, Alexandre Chan

BMC Med Inform Decis Mak· December 2022

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Diagnostic accuracy of multiparametric MRI in endometrial cancer and its adjunctive value in identifying high-risk women requiring surgical staging.
Lee Lian Chew, Bernard Ji Guang Chua, Inny Busmanis, Amos Zhi En Tay, Cindy Lim, Jack Junjie Chan

Ann Acad Med Singap· December 2022

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Differences in Practitioner Experience, Practice Type, and Profession in Attitudes Toward Growing Contact Lens Practice.
Nilesh Thite, Alfredo Desiato, Lakshmi Shinde, James S Wolffsohm, Shehzad A Naroo, Osbert Chan, Jack Chan

Eye Contact Lens· September 2022

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Hypothyroidism-induced kidney dysfunction: an under-recognized phenomenon in patients on immune checkpoint inhibitors.
Hui Zhuan Tan, Ling Zhu, Jack Junjie Chan, Tanujaa D/O Rajasekaran, Jason Chon Jun Choo

Clin Kidney J· July 2022

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Fomite Transmission Follows Invasion Ecology Principles.
Peihua Wang, Xinzhao Tong, Nan Zhang, Te Miao, Jack P T Chan

mSystems· June 2022

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Disparities in Access to Systemic Treatment for Breast Cancer in Thailand and Major Asian Territories.
Suthinee Ithimakin, Napa Parinyanitikul, Sung-Bae Kim, Yoon-Sim Yap, Janice Tsang, Jack Junjie Chan

J Breast Cancer· June 2022

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Cellular networks controlling T cell persistence in adoptive cell therapy.
Jack D Chan, Junyun Lai, Clare Y Slaney, Axel Kallies, Paul A Beavis

Nat Rev Immunol· December 2021

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Opportunities and threats to contact lens practice: A global survey perspective.
Nilesh Thite, Alfredo Desiato, Lakshmi Shinde, James S Wolffsohn, Shehzad A Naroo, Osbert Chan, Jack Chan

Cont Lens Anterior Eye· December 2021

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Analysis of efficacy of intervention strategies for COVID-19 transmission: A case study of Hong Kong.
Nan Zhang, Pak-To Jack Chan, Wei Jia, Chung-Hin Dung, Pengcheng Zhao

Environ Int· November 2021

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A Histone Deacetylase Inhibitor, Panobinostat, Enhances Chimeric Antigen Receptor T-cell Antitumor Effect Against Pancreatic Cancer.
Aesha I Ali, Minyu Wang, Bianca von Scheidt, Pilar M Dominguez, Aaron J Harrison, Jack D Chan

Clin Cancer Res· November 2021

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Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer.
Ser Yue Loo, Li Ping Toh, William Haowei Xie, Elina Pathak, Wilson Tan, Jack Chan

Sci Adv· October 2021

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MAIT cells regulate NK cell-mediated tumor immunity.
Emma V Petley, Hui-Fern Koay, Melissa A Henderson, Kevin Sek, Kirsten L Todd, Jack D Chan

Nat Commun· August 2021

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Surface touch network structure determines bacterial contamination spread on surfaces and occupant exposure.
Peihua Wang, Nan Zhang, Te Miao, Jack P T Chan, Hong Huang

J Hazard Mater· August 2021

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Early Outcomes of a National Cancer Center's Strategy Against COVID-19 Executed Through a Disease Outbreak Response Taskforce.
Jin Wei Kwek, Jack J Chan, Ravindran Kanesvaran, Michael L C Wang, Patricia S H Neo

JCO Oncol Pract· March 2021

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Cost-effectiveness of olaparib versus routine surveillance in the maintenance setting for patients with -mutated advanced ovarian cancer after response to first-line platinum-based chemotherapy in Singapore.
David Sp Tan, Jack Junjie Chan, Robert Hettle, Wrik Ghosh, Amrita Viswambaram

J Gynecol Oncol· March 2021

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